Related papers: Positive-unlabeled convolutional neural networks f…

Learning binary classifiers from positive and unlabeled data (PUL) is vital in many real-world applications, especially when verifying negative examples is difficult. Despite the impressive empirical performance of recent PUL methods,…

Cryogenic electron microscopy (Cryo-EM) has become an essential tool for capturing high-resolution biological structures. Despite its advantage in visualizations, the large storage size of Cryo-EM data file poses significant challenges for…

Positive Unlabeled (PU) learning aims to learn a binary classifier from only positive and unlabeled data, which is utilized in many real-world scenarios. However, existing PU learning algorithms cannot deal with the real-world challenge in…

Cryo-electron microscopy (cryo-EM) is a powerful technique in structural biology and drug discovery, enabling the study of biomolecules at high resolution. Significant advancements by structural biologists using cryo-EM have led to the…

Cryo-electron microscopy (cryo-EM) is a powerful technique for determining high-resolution 3D biomolecular structures from imaging data. Its unique ability to capture structural variability has spurred the development of heterogeneous…

Electroencephalography (EEG) and local field potentials (LFP) are two widely used techniques to record electrical activity from the brain. These signals are used in both the clinical and research domains for multiple applications. However,…

Resolving the structural variability of proteins is often key to understanding the structure-function relationship of those macromolecular machines. Single particle analysis using Cryogenic electron microscopy (CryoEM), combined with…

Cryo-electron microscopy (cryo-EM) has revolutionized structural biology by enabling near-atomic-level visualization of biomolecular assemblies. However, the exponential growth in cryo-EM data throughput and complexity, coupled with diverse…

Unsupervised adaptation of CLIP-based vision-language models (VLMs) for fine-grained image classification requires sensitivity to microscopic local cues. While CLIP exhibits strong zero-shot transfer, its reliance on coarse global features…

Cryo-electron microscopy (Cryo-EM) enables high-resolution imaging of biomolecules, but structural heterogeneity remains a major challenge in 3D reconstruction. Traditional methods assume a discrete set of conformations, limiting their…

Multi-label classification (MLC) faces challenges from label noise in training data due to annotating diverse semantic labels for each image. Current methods mainly target identifying and correcting label mistakes using trained MLC models,…

Learning from positive and unlabeled data is known as positive-unlabeled (PU) learning in literature and has attracted much attention in recent years. One common approach in PU learning is to sample a set of pseudo-negatives from the…

In digital pathology, segmenting densely distributed objects like glands and nuclei is crucial for downstream analysis. Since detailed pixel-wise annotations are very time-consuming, we need semi-supervised segmentation methods that can…

Learning from positive and unlabeled data (PU learning) is actively researched machine learning task. The goal is to train a binary classification model based on a training dataset containing part of positives which are labeled, and…

A single-particle cryo-electron microscopy (cryo-EM) measurement, called a micrograph, consists of multiple two-dimensional tomographic projections of a three-dimensional (3-D) molecular structure at unknown locations, taken under unknown…

The scarcity of class-labeled data is a ubiquitous bottleneck in many machine learning problems. While abundant unlabeled data typically exist and provide a potential solution, it is highly challenging to exploit them. In this paper, we…

Cryogenic electron microscopy (cryo-EM) has transformed structural biology by allowing to reconstruct 3D biomolecular structures up to near-atomic resolution. However, the 3D reconstruction process remains challenging, as the 3D structures…

Cryo-Electron Tomography (cryo-ET) is a new 3D imaging technique with unprecedented potential for resolving submicron structural detail. Existing volume visualization methods, however, cannot cope with its very low signal-to-noise ratio. In…

Enhancing cryogenic electron microscopy (cryo-EM) 3D density maps at intermediate resolution (4-8 {\AA}) is crucial in protein structure determination. Recent advances in deep learning have led to the development of automated approaches for…

Positive-Unlabeled (PU) learning aims to train a binary classifier (positive vs. negative) where only limited positive data and abundant unlabeled data are available. While widely applicable, state-of-the-art PU learning methods…