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In binary classification, there are situations where negative (N) data are too diverse to be fully labeled and we often resort to positive-unlabeled (PU) learning in these scenarios. However, collecting a non-representative N set that…

Machine Learning · Computer Science 2019-07-16 Yu-Guan Hsieh , Gang Niu , Masashi Sugiyama

Detecting illicit nodes on blockchain networks is a valuable task for strengthening future regulation. Recent machine learning-based methods proposed to tackle the tasks are using some blockchain transaction datasets with a small portion of…

Machine Learning · Computer Science 2023-07-25 Junliang Luo , Farimah Poursafaei , Xue Liu

Single-particle cryo-electron microscopy (cryo-EM) has become one of the mainstream structural biology techniques because of its ability to determine high-resolution structures of dynamic bio-molecules. However, cryo-EM data acquisition…

Machine Learning · Computer Science 2022-04-18 Quanfu Fan , Yilai Li , Yuguang Yao , John Cohn , Sijia Liu , Seychelle M. Vos , Michael A. Cianfrocco

Positive-unlabeled (PU) learning trains a binary classifier using only positive and unlabeled data. A common simplifying assumption is that the positive data is representative of the target positive class. This assumption rarely holds in…

Machine Learning · Computer Science 2020-11-10 Zayd Hammoudeh , Daniel Lowd

Positive-unlabeled (PU) learning deals with binary classification problems when only positive (P) and unlabeled (U) data are available. Many recent PU methods are based on neural networks, but little has been done to develop boosting…

Machine Learning · Computer Science 2022-12-08 Yawen Zhao , Mingzhe Zhang , Chenhao Zhang , Weitong Chen , Nan Ye , Miao Xu

Positive-Unlabeled (PU) learning tries to learn binary classifiers from a few labeled positive examples with many unlabeled ones. Compared with ordinary semi-supervised learning, this task is much more challenging due to the absence of any…

Machine Learning · Computer Science 2022-12-07 Yunrui Zhao , Qianqian Xu , Yangbangyan Jiang , Peisong Wen , Qingming Huang

Fluid ferroelectrics, a recently discovered class of liquid crystals that exhibit switchable, long-range polar order, offer opportunities in ultrafast electro-optic technologies, responsive soft matter, and next-generation energy materials.…

When dealing with binary classification of data with only one labeled class data scientists employ two main approaches, namely One-Class (OC) classification and Positive Unlabeled (PU) learning. The former only learns from labeled positive…

Machine Learning · Computer Science 2022-03-15 Farid Bagirov , Dmitry Ivanov , Aleksei Shpilman

The Machine Recognition of Crystallization Outcomes (MARCO) initiative has assembled roughly half a million annotated images of macromolecular crystallization experiments from various sources and setups. Here, state-of-the-art machine…

Protein representation learning is a challenging task that aims to capture the structure and function of proteins from their amino acid sequences. Previous methods largely ignored the fact that not all amino acids are equally important for…

Machine Learning · Computer Science 2024-04-02 Ruijie Quan , Wenguan Wang , Fan Ma , Hehe Fan , Yi Yang

Cryo-electron microscopy (cryo-EM) is an indispensable technique for determining the 3D structures of dynamic biomolecular complexes. While typically applied to image a single molecular species, cryo-EM has the potential for structure…

Computer Vision and Pattern Recognition · Computer Science 2026-03-23 Jeffrey Gu , Minkyu Jeon , Ambri Ma , Serena Yeung-Levy , Ellen D. Zhong

The crux of label-efficient semantic segmentation is to produce high-quality pseudo-labels to leverage a large amount of unlabeled or weakly labeled data. A common practice is to select the highly confident predictions as the…

Computer Vision and Pattern Recognition · Computer Science 2024-08-21 Haochen Wang , Yuchao Wang , Yujun Shen , Junsong Fan , Yuxi Wang , Zhaoxiang Zhang

Cryo-electron tomography (cryo-ET) has emerged as a powerful technique for imaging macromolecular complexes in their near-native states. However, the localization of 3D particles in cellular environments still presents a significant…

Computer Vision and Pattern Recognition · Computer Science 2025-05-27 Gokul Adethya , Bhanu Pratyush Mantha , Tianyang Wang , Xingjian Li , Min Xu

Positive--unlabeled (PU) learning considers two samples, a positive set P with observations from only one class and an unlabeled set U with observations from two classes. The goal is to classify observations in U. Class mixture proportion…

Methodology · Statistics 2020-01-13 Zhenfeng Lin , James P. Long

Planning for diverse real-world robotic tasks necessitates to know and write all constraints. However, instances exist where these constraints are either unknown or challenging to specify accurately. A possible solution is to infer the…

Robotics · Computer Science 2025-01-17 Baiyu Peng , Aude Billard

Given only positive (P) and unlabeled (U) data, PU learning can train a binary classifier without any negative data. It has two building blocks: PU class-prior estimation (CPE) and PU classification; the latter has been well studied while…

Machine Learning · Computer Science 2022-06-06 Yu Yao , Tongliang Liu , Bo Han , Mingming Gong , Gang Niu , Masashi Sugiyama , Dacheng Tao

Electron cryo-microscopy (cryo-EM) produces three-dimensional (3D) maps of the electrostatic potential of biological macromolecules, including proteins. Along with knowledge about the imaged molecules, cryo-EM maps allow de novo atomic…

Quantitative Methods · Quantitative Biology 2023-02-09 Kiarash Jamali , Dari Kimanius , Sjors H. W. Scheres

In the field of transmission electron microscopy, data interpretation often lags behind acquisition methods, as image processing methods often have to be manually tailored to individual datasets. Machine learning offers a promising approach…

Image and Video Processing · Electrical Eng. & Systems 2021-07-07 C. K. Groschner , Christina Choi , M. C. Scott

This paper presents a CLIP-based unsupervised learning method for annotation-free multi-label image classification, including three stages: initialization, training, and inference. At the initialization stage, we take full advantage of the…

Computer Vision and Pattern Recognition · Computer Science 2024-03-08 Rabab Abdelfattah , Qing Guo , Xiaoguang Li , Xiaofeng Wang , Song Wang

3D medical image segmentation is a challenging task with crucial implications for disease diagnosis and treatment planning. Recent advances in deep learning have significantly enhanced fully supervised medical image segmentation. However,…

Image and Video Processing · Electrical Eng. & Systems 2025-06-23 Runmin Jiang , Zhaoxin Fan , Junhao Wu , Lenghan Zhu , Xin Huang , Tianyang Wang , Heng Huang , Min Xu
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