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The imaging performance of a high-resolution preclinical microPET system employing liquid xenon as the gamma ray detection medium was simulated. The arrangement comprises a ring of detectors consisting of trapezoidal LXe time projection…

Medical Physics · Physics 2012-03-23 A. Miceli , J. Glister , A. Andreyev , D. Bryman , L. Kurchaninov , P. Lu , A. Muennich , F. Retiere , V. Sossi

A detector using liquid Xenon (LXe) in the scintillation mode is studied for Positron Emission Tomography (PET) of small animals. Its specific design aims at taking full advantage of the Liquid Xenon scintillation properties. This paper…

Organ-specific, targeted Field-of-View (FoV) Positron Emission Tomography (PET)/Magnetic Resonance Imaging (MRI) inserts are viable solutions for a number of imaging tasks where whole-body PET/MRI systems lack the necessary sensitivity and…

Instrumentation and Detectors · Physics 2019-09-19 J. M. C. Brown , S. E. Brunner , D. R. Schaart

In the present work we describe the design, construction, and testing of the optical prototype developed for the BOLDPET project, with the objective of creating a PET detection module with high spatial and time resolution. The BOLDPET…

PET provides in vivo molecular and functional imaging capability that is crucial to studying the interaction of plant with changing environment at the whole-plant level. We have developed a dedicated plant PET imager that features high…

Instrumentation and Detectors · Physics 2014-09-22 Qiang Wang , Aswin J. Mathews , Ke Li , Jie Wen , Sergey Komarov , Joseph A. O'Sullivan , Yuan-Chuan Tai

Two major challenges in time-of-flight positron emission tomography (TOF-PET) are low spatial resolution and high radioactive dose to the patient, both of which result from limitations in detection technology rather than fundamental…

The growing interest in human-grade total body positron emission tomography (PET) systems has also application in small animal research. Due to the existing limitations in human-based studies involving drug development and novel treatment…

PET is a functional imaging technique based on detection of annihilation photons following beta decay producing positrons. In this paper, we present the concept of a new PET system for preclinical applications consisting of a ring of twelve…

Instrumentation and Detectors · Physics 2015-03-19 A. Miceli , P. Amaudruz , F. Benard , D. A. Bryman , L. Kurchaninov , J. P. Martin , A. Muennich , F. Retiere , T. J. Ruth , V. Sossi , A. J. Stoessl

Positron Emission Tomography (PET) is a functional imaging modality that enables the visualization of biochemical and physiological processes across various tissues. Recently, deep learning (DL)-based methods have demonstrated significant…

Image and Video Processing · Electrical Eng. & Systems 2026-01-16 Yiran Sun , Osama Mawlawi

Monte Carlo simulations are increasingly used in scintigraphic imaging to model imaging systems and to develop and assess tomographic reconstruction algorithms and correction methods for improved image quantitation. GATE (GEANT 4…

Instrumentation and Detectors · Physics 2009-11-10 D. Lazaro , I. Buvat , G. Loudos , D. Strul , G. Santin , N. Giokaris , D. Donnarieix , L. Maigne , V. Spanoudaki , S. Styliaris , S. Staelens , V. Breton

This work is the second part of a simulation study investigating the processing of densely packed and moving granular assemblies by positron emission particle tracking (PEPT). Since medical PET scanners commonly used for PEPT are very…

Single Photon Emission Computed Tomography (SPECT) is a non-invasive imaging modality, frequently used in myocardial perfusion imaging. The biggest challenges facing the majority of clinical SPECT systems are low sensitivity, poor…

Medical Physics · Physics 2021-03-30 Narayan Bhusal

We present first results from a Positron Emission Tomography (PET) scanner demonstrator based on Resistive Plate Chambers and specialized for brain imaging. The device features a 30 cm wide cubic field-of-view and each detector comprises 40…

A detector using liquid Xenon in the scintillation mode is studied for Positron Emission Tomography (PET). The specific design aims at taking full advantage of the liquid Xenon properties. It does feature a promising insensitive to any…

Currently inorganic scintillator detectors are used in all commercial Time of Flight Positron Emission Tomograph (TOF-PET) devices. The J-PET collaboration investigates a possibility of construction of a PET scanner from plastic…

Positron emission tomography (PET) is a medical imaging method based on the measurement of concentrations of positron-emitting radionuclides in a living body. In the PET imaging system, glucose is labeled with a positron-emitting…

Signal Processing · Electrical Eng. & Systems 2022-09-27 Mehmet Akif Ozdemir , Ali Tangel

Objective: Positron Emission Tomography (PET) has been a commonly used imaging modality in broad clinical applications. One of the most important tradeoffs in PET imaging is between image quality and radiation dose: high image quality comes…

Image and Video Processing · Electrical Eng. & Systems 2024-04-18 Shaoyan Pan , Elham Abouei , Junbo Peng , Joshua Qian , Jacob F Wynne , Tonghe Wang , Chih-Wei Chang , Justin Roper , Jonathon A Nye , Hui Mao , Xiaofeng Yang

Positron Emission Tomography (PET) is a Nuclear Medicine technique that creates images that allow the study of metabolic activity and organ function using radiopharmaceuticals. Continuous improvement of scintillation detectors for radiation…

Total-body positron emission tomography (PET) imaging has the potential to transform medical care of a number of diseases and augment our knowledge of systems biology. Various detector designs and geometries are currently under development…

Improving the coincidence time resolution (CTR) of time-of-flight positron emission tomography (TOF-PET) systems to achieve a higher signal-to-noise ratio (SNR) gain or even direct positron emission imaging (dPEI) is of paramount importance…

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