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Step meandering due to a deterministic morphological instability on vicinal surfaces during growth is studied. We investigate nonlinear dynamics of a step model with asymmetric step kinetics, terrace and line diffusion, by means of a…

Statistical Mechanics · Physics 2009-10-31 F. Gillet , O. Pierre-Louis , C. Misbah

Natural populations often show enhanced genetic drift consistent with a strong skew in their offspring number distribution. The skew arises because the variability of family sizes is either inherently strong or amplified by population…

Populations and Evolution · Quantitative Biology 2022-01-13 Takashi Okada , Oskar Hallatschek

We consider a single genetic locus with two alleles $A_1$ and $A_2$ in a large haploid population. The locus is subject to selection and two-way, or recurrent, mutation. Assuming the allele frequencies follow a Wright-Fisher diffusion and…

Probability · Mathematics 2024-04-29 Wai-Tong Louis Fan , John Wakeley

Ecological systems comprise an astonishing diversity of species that cooperate or compete with each other forming complex mutual dependencies. The minimum requirements to maintain a large species diversity on long time scales are in general…

Populations and Evolution · Quantitative Biology 2012-09-10 Joachim Mathiesen , Namiko Mitarai , Kim Sneppen , Ala Trusina

In this paper, we proposed a stochastic model which describes two species of particles moving in counterflow. The model generalizes the theoretical framework describing the transport in random systems since particles can work as mobile…

Soft Condensed Matter · Physics 2017-08-09 Eduardo Velasco Stock , Roberto da Silva , Henrique Almeida Fernandes

Beneficial reversals of dominance reduce the costs of genetic trade-offs and can enable selection to maintain genetic variation for fitness. Beneficial dominance reversals are characterized by the beneficial allele for a given context (e.g.…

Populations and Evolution · Quantitative Biology 2024-03-28 Karl Grieshop , Eddie K. H. Ho , Katja R. Kasimatis

We study flocking in one dimension, introducing a lattice model in which particles can move either left or right. We find that the model exhibits a continuous nonequilibrium phase transition from a condensed phase, in which a single `flock'…

Statistical Mechanics · Physics 2009-10-31 O. J. O'Loan , M. R. Evans

We introduce a multi-allele Wright-Fisher model with non-recurrent, reversible mutation and directional selection. In this setting, the allele frequencies at a single locus track the path of a hybrid jump-diffusion process with state space…

Probability · Mathematics 2023-02-16 Ingemar Kaj , Carina F. Mugal , Rebekka Müller

The contribution to an organism's phenotype from one genetic locus may depend upon the status of other loci. Such epistatic interactions among loci are now recognized as fundamental to shaping the process of adaptation in evolving…

Populations and Evolution · Quantitative Biology 2012-12-18 Jeremy A. Draghi , Joshua B. Plotkin

We review and extend results for mutation, selection, genetic drift, and migration in a one-dimensional continuous population. The population is described by a continuous limit of the stepping stone model, which leads to the stochastic…

Populations and Evolution · Quantitative Biology 2011-04-14 K. S. Korolev , Mikkel Avlund , Oskar Hallatschek , David R. Nelson

Animal locomotion is often subject to constraints arising from anatomical/physiological asymmetries. We use the nematode C.~elegans as a minimal model system to ask whether such constraints might shape locomotion patterns optimized during…

Neurons and Cognition · Quantitative Biology 2024-01-17 W. Mathijs Rozemuller , Steffen Werner , Antonio Carlos Costa , Liam O'Shaughnessy , Greg J. Stephens , Thomas S. Shimizu

We study the lattice random walk dynamics in a heterogeneous space of two media separated by an interface and having different diffusivity and bias. Depending on the position of the interface, there exist two exclusive ways to model the…

Statistical Mechanics · Physics 2023-01-06 Debraj Das , Luca Giuggioli

Chromatin is repeatedly deformed in vivo during transcription, nuclear remodeling, and confined migration - yet how mechanical response varies from locus to locus, and how it relates to epigenetic state, remains unclear. We develop a theory…

Soft Condensed Matter · Physics 2025-12-30 Guang Shi , D. Thirumalai

In this work, we characterize the solution of a system of elliptic integro-differential equations describing a phenotypically structured population subject to mutation, selection and migration between two habitats. Assuming that the effects…

Analysis of PDEs · Mathematics 2016-12-20 Sepideh Mirrahimi

In subdivided populations, migration acts together with selection and genetic drift and determines their evolution. Building up on a recently proposed method, which hinges on the emergence of a time scale separation between local and global…

Populations and Evolution · Quantitative Biology 2015-03-24 Pierangelo Lombardo , Andrea Gambassi , Luca Dall'Asta

We study the evolution of a wave packet in a nonlinear Schr\"odinger lattice equation subject to a dc bias. In the absence of nonlinearity all normal modes are spatially localized giving rise to a Stark ladder with an equidistant eigenvalue…

Statistical Mechanics · Physics 2010-01-29 Dmitry O. Krimer , Ramaz Khomeriki , Sergej Flach

The evolution of genetic systems has been analyzed through the use of modifier gene models, in which a neutral gene is posited to control the transmission of other genes under selection. Analysis of modifier gene models has found the…

Populations and Evolution · Quantitative Biology 2013-02-04 Lee Altenberg

We investigate a multi-locus evolutionary model which is based on the DNA shuffling protocol widely applied in \textit{in vitro} directed evolution. This model incorporates selection, recombination and point mutations. The simplicity of the…

Biological Physics · Physics 2009-11-10 Weiqun Peng , Herbert Levine , Terence Hwa , David A. Kessler

We consider a heteroclinic network in the framework of winnerless competition of species. It consists of two levels of heteroclinic cycles. On the lower level, the heteroclinic cycle connects three saddles, each representing the survival of…

Adaptation and Self-Organizing Systems · Physics 2018-12-26 Maximilian Voit , Hildegard Meyer-Ortmanns

We study the impact of a hard selective sweep on the genealogy of partially linked neutral loci in the vicinity of the positively selected allele. We consider a sexual population of stochastically varying size and, focusing on two…

Probability · Mathematics 2016-05-10 Rebekka Brink-Spalink , Charline Smadi