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X-ray computed tomography (CT) is widely used for medical diagnosis and treatment planning; however, concerns about ionizing radiation exposure drive efforts to optimize image quality at lower doses. This study introduces Poisson Flow…

Image and Video Processing · Electrical Eng. & Systems 2025-02-25 Dennis Hein , Grant Stevens , Adam Wang , Ge Wang

Computed tomography (CT) has been developed as a non-destructive technique for observing minute internal images of samples. It has been difficult to obtain photo-realistic (clean or clear) CT images due to various unwanted artifacts…

Quantum Physics · Physics 2023-09-12 Kyungtaek Jun

Purpose: To develop a DL-based PBSPT dose prediction workflow with high accuracy and balanced complexity to support on-line adaptive proton therapy clinical decision and subsequent replanning. Methods: PBSPT plans of 103 prostate cancer…

Proton radiotherapy promises accurate dose delivery to a tumor and minimal dose deposition to all other tissues. However, in practice the planned dose distribution may not conform to the actual one due to noisy data and different types of…

Medical Physics · Physics 2018-09-07 Jaroslav Albert , Rudi Labarbe , Edmond Sterpin

Kidney stone disease results in millions of annual visits to emergency departments in the United States. Computed tomography (CT) scans serve as the standard imaging modality for efficient detection of kidney stones. Various approaches…

Image and Video Processing · Electrical Eng. & Systems 2024-08-02 Fangyijie Wang , Guenole Silvestre , Kathleen M. Curran

In living organisms the positron-electron annihilation (occurring during the PET imaging) proceeds in about 30% via creation of a metastable ortho-positronium atom. In the tissue, due to the pick-off and conversion processes, over 98% of…

Dual-energy computed tomography (DECT) has shown great potential and promising applications in advanced imaging fields for its capabilities of material decomposition. However, image reconstructions and decompositions under sparse views…

Medical Physics · Physics 2016-08-01 Lei Li , Ailong Cai , Linyuan Wang , Bin Yan , Hanming Zhang , Zhizhong Zheng , Wenkun Zhang , Wanli Lu , Guoen Hu

Computed tomography (CT) is a beneficial imaging tool for diagnostic purposes. CT scans provide detailed information concerning the internal anatomic structures of a patient, but present higher radiation dose and costs compared to X-ray…

Image and Video Processing · Electrical Eng. & Systems 2024-03-05 Benjamin Paulson , Joshua Goldshteyn , Sydney Balboni , John Cisler , Andrew Crisler , Natalia Bukowski , Julia Kalish , Theodore Colwell

Photon-counting CT (PCCT) provides superior image quality with higher spatial resolution and lower noise compared to conventional energy-integrating CT (EICT), but its limited clinical availability restricts large-scale research and…

Computer Vision and Pattern Recognition · Computer Science 2026-04-09 Junqi Liu , Xinze Zhou , Wenxuan Li , Scott Ye , Arkadiusz Sitek , Xiaofeng Yang , Yucheng Tang , Daguang Xu , Kai Ding , Kang Wang , Yang Yang , Alan L. Yuille , Zongwei Zhou

Patients undergoing a mechanical thrombectomy procedure usually have a multi-detector CT (MDCT) scan before and after the intervention. The image quality of the flat panel detector CT (FDCT) present in the intervention room is generally…

Image and Video Processing · Electrical Eng. & Systems 2025-08-28 Hélène Corbaz , Anh Nguyen , Victor Schulze-Zachau , Paul Friedrich , Alicia Durrer , Florentin Bieder , Philippe C. Cattin , Marios N Psychogios

Next generation online and real-time adaptive radiotherapy workflows require precise particle transport simulations in sub-second times, which is unfeasible with current analytical pencil beam algorithms (PBA) or stochastic Monte Carlo (MC)…

Medical Physics · Physics 2022-02-08 Oscar Pastor-Serrano , Zoltán Perkó

Computed Tomography (CT) is a key 3D imaging technology that fundamentally relies on the compute-intense back-projection operation to generate 3D volumes. GPUs are typically used for back-projection in production CT devices. However, with…

Distributed, Parallel, and Cluster Computing · Computer Science 2021-04-28 Peng Chen , Mohamed Wahib , Xiao Wang , Shinichiro Takizawa , Takahiro Hirofuchi , Hirotaka Ogawa , Satoshi Matsuoka

In positron emission tomography (PET), time-of-flight (TOF) information localizes source positions along lines of response. Cherenkov-radiator-integrated microchannel-plate photomultiplier tubes have achieved 30 ps TOF resolution,…

Radiation dose is an important performance indicator of a dedicated breast CT (DBCT). In this paper, the method of putting thermoluminescent dosimeters (TLD) into a breast shaped PMMA phantom to study the dose distribution in breasts was…

Medical Physics · Physics 2013-05-14 Shen Shan-Wei , Wang Yan-Fang , Shu Hang , Tang Xiao , Wei Cun-Feng , Song Yu-Shou , Shi Rong-Jian , Wei Long

Studies of the human brain during natural activities, such as locomotion, would benefit from the ability to image deep brain structures during these activities. While Positron Emission Tomography (PET) can image these structures, the bulk…

Robotics · Computer Science 2023-11-30 Junxiang Wang , Iulian I. Iordachita , Peter Kazanzides

In computed tomography (CT) reconstruction, scattering causes server quality degradation of the reconstructed CT images by introducing streaks and cupping artifacts which reduce the detectability of low contrast objects. Monte Carlo (MC)…

Image and Video Processing · Electrical Eng. & Systems 2022-02-01 Ammar Alsaffar , Steffen Kieß , Kaicong Sun , Sven Simon

Positron Emission Tomography (PET) is a Nuclear Medicine technique that creates images that allow the study of metabolic activity and organ function using radiopharmaceuticals. Continuous improvement of scintillation detectors for radiation…

Purpose: Radiotherapy commonly relies on CT, but there is growing interest in using hybrid PET/MR. Therefore, dedicated hardware setups have been proposed for PET/MR systems which enable imaging in radiotherapy treatment position. These…

Medical Physics · Physics 2024-11-14 R. M. Winter , O. Engelsen , O. J. Bratting , N. Brekke , J. Sæterstøl , O. Sæther , K. R. Redalen

Automated medical image classification with convolutional neural networks (CNNs) has great potential to impact healthcare, particularly in resource-constrained healthcare systems where fewer trained radiologists are available. However,…

Image and Video Processing · Electrical Eng. & Systems 2020-03-31 Sarah M. Hooper , Jared A. Dunnmon , Matthew P. Lungren , Sanjiv Sam Gambhir , Christopher Ré , Adam S. Wang , Bhavik N. Patel

A proton irradiation site for silicon detectors has been developed and commissioned at the Bonn Isochronous Cyclotron. The accelerator provides 14 MeV proton beams of up to 1 $\mu$A at beam widths of a few mm to the setup. Devices Under…

Instrumentation and Detectors · Physics 2024-05-07 Pascal Wolf , Dennis Sauerland , Reinhard Beck , Jochen Dingfelder
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