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Collective cell migration is crucial in many biological processes such as wound healing, tissue morphogenesis, and tumor progression. The leading front of a collective migrating epithelial cell layer often destabilizes into multicellular…

Biological Physics · Physics 2020-05-07 Yanjun Yang , Herbert Levine

We study colloidal particles in a nematic-liquid-crystal-filled microfluidic channel and show how elastic interactions between the particle and the channel wall lead to different particle dynamics compared with conventional microfluidics.…

Soft Condensed Matter · Physics 2017-07-31 Sourav Mondal , Apala Majumdar , Ian M. Griffiths

The motion of several plates in an inviscid and incompressible fluid is studied numerically using a vortex sheet model. Two to four plates are initially placed in-line, separated by a specified distance, and actuated in the vertical…

Fluid Dynamics · Physics 2026-05-19 Monika Nitsche , Anand U. Oza , Michael Siegel

Mixing in numerous medical and chemical applications, involving overly long microchannels, can be enhanced by inducing flow instabilities. The channel length, is thus shortened in the inertial microfluidics regime due to the enhanced…

Fluid Dynamics · Physics 2019-05-13 Saunak Sengupta , Sukhendu Ghosh , Sandeep Saha , Suman Chakraborty

The dynamics of entrainment of finite-size heavy particles in a turbulent open channel flow over a smooth surface are analyzed. Three types of simulations, namely with freely moving, rotation-constrained, and spanwise-motion-constrained…

Fluid Dynamics · Physics 2026-01-28 Tatia Bzikadze , Markus Weyrauch , Markus Uhlmann

We study the linear stability of the flow of a viscous electrically conducting capillary fluid on a planar fixed plate in the presence of gravity and a uniform magnetic field. We first confirm that the Squire transformation for MHD is…

Fluid Dynamics · Physics 2017-05-24 D. Giannakis , R. Rosner , P. Fischer

A flexible membrane deforming its shape in time can self-propel in a viscous fluid. Alternatively, if the membrane is anchored, its deformation will lead to fluid transport. Past work in this area focused on situations where the deformation…

Soft Condensed Matter · Physics 2013-02-12 Arthur A. Evans , Eric Lauga

This work analyzes the viscous flow and elastic deformation created by the forced axial motion of a rigid cylinder within an elastic liquid-filled tube. The examined configuration is relevant to various minimally invasive medical procedures…

Soft Condensed Matter · Physics 2019-05-15 Amit Vurgaft , Shai B. Elbaz , Amir D. Gat

We study the interaction-induced migration of bubbles in shear flow and observe that bubbles suspended in elastoviscoplastic emulsions organise into chains aligned in the flow direction, similarly to particles in viscoelastic fluids. To…

Soft Condensed Matter · Physics 2023-04-25 Blandine Feneuil , Kazi Tassawar Iqbal , Atle Jensen , Luca Brandt , Outi Tammisola , Andreas Carlson

One of the central appealing properties of magnetic gels and elastomers is that their elastic moduli can reversibly be adjusted from outside by applying magnetic fields. The impact of the internal magnetic particle distribution on this…

Soft Condensed Matter · Physics 2014-10-22 Giorgio Pessot , Peet Cremer , Dmitry Y. Borin , Stefan Odenbach , Hartmut Löwen , Andreas M. Menzel

Cell migration in fibreous extracellular matrix (ECM) is crucial to many physiological and pathological processes such as tissue regeneration, immune response and cancer progression. During migration, individual cells can generate active…

Cell Behavior · Quantitative Biology 2019-10-16 Yu Zheng , Hanqing Nan , Qihui Fan , Xiaochen Wang , Liyu Liu , Ruchuan Liu , Fangfu Ye , Bo Sun , Yang Jiao

The phenomenological model for cell shape deformation and cell migration (Chen et.al. 2018; Vermolen and Gefen 2012) is extended with the incorporation of cell traction forces and the evolution of cell equilibrium shapes as a result of cell…

Cell Behavior · Quantitative Biology 2021-04-27 Qiyao Peng , Fred Vermolen , Daphne Weihs

We analyze motility-induced phase separation and bubbly phase separation in a two-dimensional lattice model of self-propelled particles. We compare systems where the dense (liquid) phase has slab and droplet geometries. We find that…

Soft Condensed Matter · Physics 2025-03-18 Liheng Yao , Robert L. Jack

Cancer cell migration between different body parts is the driving force behind cancer metastasis, which is the main cause of mortality of patients. Migration of cancer cells often proceeds by penetration through narrow cavities in locally…

Cell Behavior · Quantitative Biology 2023-05-02 Qiyao Peng , Fred J Vermolen , Daphne Weihs

Wall-bounded sedimentation of spherical particles at low particle Reynolds numbers $Re_\text{P}\lessapprox 0.1$ under the influence of elastic deformation was investigated experimentally. The complete kinematics of both elastic and rigid…

Fluid Dynamics · Physics 2024-09-12 Isabell Noichl , Clarissa Schönecker

We construct a boundary integral representation for the low-Reynolds-number flow in a channel in the presence of freely-suspended particles (or droplets) of arbitrary size and shape. We demonstrate that lubrication theory holds away from…

Fluid Dynamics · Physics 2018-01-17 Itzhak Fouxon , Zhouyang Ge , Luca Brandt , Alexander Leshansky

Although understanding the collective migration of cells, such as that seen in epithelial sheets, is essential for understanding diseases such as metastatic cancer, this motion is not yet as well characterized as individual cell migration.…

Transport properties of particles in confining geometries show very specific characteristics as lateral drift, oscillatory movement between lateral walls or the deformation of flexible fibers. These dynamics result from viscous friction…

Fluid Dynamics · Physics 2020-04-03 M. Bechert , J. Cappello , M. Daïeff , F. Gallaire , A. Lindner , C. Duprat

In vascular targeted therapies, blood-borne carriers should realize sustained drug release from the luminal side towards the diseased tissue. In this context, such carriers are required to firmly adhere to the vessel walls for a sufficient…

Fluid Dynamics · Physics 2022-10-13 A. Coclite , G. Pascazio , M. D. de Tullio , P. Decuzzi

Recent numerical analyses to optimize the design of microfluidic devices for more effective entrapment or segregation of surrogate circulating tumor cells (CTCs) from healthy cells have been reported in the literature without concurrently…

Computational Physics · Physics 2020-06-23 Hakan Başağaoğlu , Justin Blount , Sauro Succi , Christopher J. Freitas
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