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Viscoelastic microfluidic devices are promising for various microscale procedures such as particle sorting and separation. In this study, we perform three dimensional computational investigation of a particle in a viscoelastic channel flow…

Fluid Dynamics · Physics 2019-10-29 Amir Hossein Raffiee , Arezoo M. Ardekani , Sadegh Dabiri

The motility of a fish keratocyte on a flat substrate exhibits two distinct regimes: the non-migrating and the migrating one. In both configurations the shape is fixed in time and, when the cell is moving, the velocity is constant in…

Cell Behavior · Quantitative Biology 2016-06-29 Davide Ambrosi , Anna Zanzottera

The dynamics of dense finite-size particles in vertical channel flows of Newtonian and viscoelastic carrier fluids are examined using particle resolved simulations. Comparison to neutrally buoyant particles in the same configuration…

Fluid Dynamics · Physics 2021-05-26 Amir Esteghamatian , Tamer A. Zaki

The displacement of a fluid by another less viscous one in a quasi-two dimensional geometry typically leads to complex fingering patterns. In an isotropic system, dense-branching growth arises, which is characterized by repeated…

Fluid Dynamics · Physics 2021-01-19 Qing Zhang , Amin Amooie , Martin Z. Bazant , Irmgard Bischofberger

Particles in pressure-driven channel flow are often inhomogeneously distributed. Two modes of low-Reynolds number instability, absent in Poiseuille flow of clean fluid, are created by inhomogeneous particle loading, and their mechanism is…

Fluid Dynamics · Physics 2024-11-27 Anup Kumar , Rama Govindarajan

Very large-scale motions (VLSMs) and large-scale motions (LSMs) coexist at moderate Reynolds numbers in a very long open channel flow. Direct numerical simulations two-way coupled with inertial particles are analysed using spectral…

Fluid Dynamics · Physics 2019-02-19 Guiquan Wang , David Richter

We study the transport of bacteria in a porous media modeled by a square channel containing one cylindrical obstacle via molecular dynamics simulations coupled to a lattice Boltzmann fluid. Our bacteria model is a rod-shaped rigid body…

Soft Condensed Matter · Physics 2020-11-30 Miru Lee , Christoph Lohrmann , Kai Szuttor , Harold Auradou , Christian Holm

Elastic capsules, prepared from droplets or bubbles attached to a capillary (as in a pendant drop tensiometer), can be deflated by suction through the capillary. We study this deflation and show that a combined analysis of the shape and…

Soft Condensed Matter · Physics 2013-10-21 Sebastian Knoche , Dominic Vella , Elodie Aumaitre , Patrick Degen , Heinz Rehage , Pietro Cicuta , Jan Kierfeld

A colloidal particle driven by externally actuated rotation can self-propel parallel to a rigid boundary by exploiting the hydrodynamic coupling that surfaces induce between translation and rotation. As such a roller moves along the…

Fluid Dynamics · Physics 2020-02-20 Alexander Chamolly , Eric Lauga , Soichiro Tottori

This work investigates the motion of neutrally-buoyant, slightly deformable straight and curved prolate capsules in unbounded simple shear flow at zero Reynolds number using direct simulations. The curved capsules serve as a model for the…

Fluid Dynamics · Physics 2018-11-29 Xiao Zhang , Wilbur A. Lam , Michael D. Graham

Though ubiquitous in many engineering applications, including drug delivery, the compound droplet hydrodynamics in confined geometries have been barely surveyed. For the first time, this study thoroughly investigates the hydrodynamics of a…

The mobility of particles in fluid membranes is a fundamental aspect of many biological processes. In a 1975 paper [1], Saffman and Delbr\"uck demonstrated how the presence of external Stokesian solvents is crucial in regularising the…

Biological Physics · Physics 2025-01-10 Marco Vona , Eric Lauga

Collections of cells exhibit coherent migration during morphogenesis, cancer metastasis, and wound healing. In many cases, bigger clusters split, smaller sub-clusters collide and reassemble, and gaps continually emerge. The connections…

Biological Physics · Physics 2021-03-31 Ushasi Roy , Andrew Mugler

The migration of cells is relevant for processes such as morphogenesis, wound healing, and invasion of cancer cells. In order to move, single cells deform cyclically. However, it is not understood how these shape oscillations influence…

Biological Physics · Physics 2019-09-04 Matteo Campo , Simon K. Schnyder , John J. Molina , Thomas Speck , Ryoichi Yamamoto

Spontaneous growth of long-wavelength deformations is a defining feature of active fluids with orientational order. We investigate the effect of biaxial rectangular confinement on the instability of initially shear-aligned 3D isotropic…

Soft Condensed Matter · Physics 2021-01-04 Pooja Chandrakar , Minu Varghese , S. Ali Aghvami , Aparna Baskaran , Zvonimir Dogic , Guillaume Duclos

We investigate the dynamics of elastic capsules suspended in two-dimensional active nematic fluids using lattice Boltzmann simulations. The capsules, modeled as flexible membranes enclosing active internal regions, exhibit a rich variety of…

Soft Condensed Matter · Physics 2026-04-13 Júlio P. A. Santos , Margarida M. Telo da Gama , Rodrigo C. V. Coelho

Cell migration plays a fundamental role in numerous physiological processes, including embryonic development, wound healing, and cancer metastasis. While cell-cell adhesion is known to regulate motion by shaping cell morphology and…

Biological Physics · Physics 2026-03-09 Anh Q. Nguyen , Pradip K. Bera , Jacob Notbohm , Dapeng Bi

We investigate the mechanisms by which inertial solid particles modulate turbulence and alter the fluid mass transport in dense turbulent liquid-solid flows. To this end, we perform Euler-Lagrange simulations at friction Reynolds number…

Fluid Dynamics · Physics 2024-06-13 Jonathan S. Van Doren , M. Houssem Kasbaoui

A rigid object moving in a viscous fluid and in close proximity with an elastic wall experiences self-generated elastohydrodynamic interactions. This has been the subject of an intense research activity, with a recent and growing attention…

Soft Condensed Matter · Physics 2023-07-04 Aditya Jha , Yacine Amarouchene , Thomas Salez

Cell migration is important in many biological processes, including embryonic development, cancer metastasis, and wound healing. In these tissues, a cell's motion is often strongly constrained by its neighbors, leading to glassy dynamics.…

Biological Physics · Physics 2016-01-20 Dapeng Bi , J. H. Lopez , J. M. Schwarz , M. Lisa Manning