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Single and collective cell migration are fundamental processes critical for physiological phenomena ranging from embryonic development and immune response to wound healing and cancer metastasis. To understand cell migration from a physical…

Biological Physics · Physics 2023-10-10 David B. Brückner , Chase P. Broedersz

Using high-fidelity numerical simulations based on a lattice Boltzmann framework, the advection-enhanced transport of a passive scalar from a prolate spheroid in simple shear flow has been thoroughly investigated across various parameters,…

Fluid Dynamics · Physics 2025-10-15 Yanxing Wang , Hui Wan , Tie Wei , Fangjun Shu

The collective chemotaxis of multicellular clusters is an important phenomenon in various physiological contexts, ranging from embryonic development to cancer metastasis. Such clusters often display interesting shape dynamics and…

Tissues and Organs · Quantitative Biology 2025-06-03 Monika Sanoria , Gema Malet-Engra , Giorgio Scita , Nir Gov , Ajay Gopinathan

A simple model accounting for the ejection of heavy particles from the vortical structures of a turbulent flow is introduced. This model involves a space and time discretization of the dynamics and depends on only two parameters: the…

Chaotic Dynamics · Physics 2009-11-13 Jeremie Bec , Raphael Chetrite

Cell motility underlies many biological processes, including cancer metastasis, bacterial infection, and evolutionary adaptation. We introduce a non-equilibrium single-cell motility model inspired by the generalized Langevin equation, which…

Biological Physics · Physics 2026-01-27 Anton Klimek , Prince V. Baruah , Prerna Sharma , Roland R. Netz

Soft particles can be better emulsifiers than hard particles because they stretch at fluid interfaces. This deformation can increase adsorption energies by orders of magnitude relative to rigid particles. The deformation of a particle at an…

Soft Condensed Matter · Physics 2015-07-15 Robert W. Style , Lucio Isa , Eric R. Dufresne

Recent biological experiments have shown that certain types of cells are able to move in structured and confined environment even without the activation of focal adhesion. Focusing on this particular phenomenon and based on previous works,…

Analysis of PDEs · Mathematics 2022-12-05 Chiara Giverso , Gaspard Jankowiak , Luigi Preziosi , Christian Schmeiser

From particle lifting in atmospheric boundary layers to dust ingestion in jet engines, the transport and deposition of inertial particles in wall-bounded turbulent flows are prevalent in both nature and industry. Due to triboelectrification…

Fluid Dynamics · Physics 2025-05-14 Xuan Ruan , Miguel X. Diaz-Lopez , Matthew T. Gorman , Rui Ni

The transport of deformable objects including polymer particles, vesicles and cells, has been a subject of interest for several decades where the majority of experimental and theoretical studies have been focused on circular tubes. Due to…

Soft Condensed Matter · Physics 2017-11-28 Shamim M. Ahmmed , Naureen S. Suteria , Valeria Garbin , Siva A. Vanapalli

Selective withdrawal extracts only a single phase from a stratified multi-layer system. Entrainment occurs when a critical condition draws up the static layer which is not being withdrawn. Existing studies provide robust scalings within…

Fluid Dynamics · Physics 2026-01-07 Sabbir Hassan , Arsalan Abutalebi , Sukalyan Bhattacharya , Gordon F. Christopher

Two-way coupled direct numerical simulations are used to investigate the effects of inertial particles on self-sustained, turbulent coherent structures (i.e. the so-called the regeneration cycle) in plane Couette flow at low Reynolds number…

Fluid Dynamics · Physics 2019-01-30 Guiquan Wang , David Richter

The steady state motion of cylindrical droplets under the action of external body force is investigated both theoretically and via lattice Boltzmann simulation. As long as the shape-invariance of droplet is maintained, the droplet's…

Soft Condensed Matter · Physics 2011-02-11 Nasrollah Moradi , Fathollah Varnik , Ingo Steinbach

This study investigates the lift force acting on a finite-size, neutrally buoyant spherical particle suspended in a liquid while flowing through a shallow channel at low Reynolds numbers. Using an immersed boundary method, we calculate the…

Fluid Dynamics · Physics 2026-04-29 Guiquan Wang , Willem Van Roy , Chengxun Liu , Tim Stakenborg , Benjamin Jones

We address the folding induced by differential growth in soft layered solids via an elementary model that consists of a soft growing neo-Hookean elastic layer adhered to a deep elastic substrate. As the layer/substrate modulus ratio is…

Soft Condensed Matter · Physics 2015-09-30 Tuomas Tallinen , John S. Biggins

The collective migration of epithelial groups of cells plays a central role in processes such as embryo development, wound healing, and cancer invasion. While finite cell clusters are known to collectively migrate in response to external…

Recent experiments suggest that the interplay between cells and the mechanics of their substrate gives rise to a diversity of morphological and migrational behaviors. Here, we develop a Cellular Potts Model of polarizing cells on a…

We consider nonequilibrium transport in a simple chain of identical mechanical cells in which particles move around. In each cell, there is a rotating disc, with which these particles interact, and this is the only interaction in the model.…

Statistical Mechanics · Physics 2008-07-15 Jean-Pierre Eckmann , Carlos Mejia-Monasterio , Emmanuel Zabey

The depletion interaction mediated by non-adsorbing polymers promotes condensation and assembly of repulsive colloidal particles into diverse higher-order structures and materials. One example, with particularly rich emergent behaviors, is…

Soft Condensed Matter · Physics 2016-02-23 Louis Kang , Thomas Gibaud , Zvonimir Dogic , T. C. Lubensky

The encapsulation of active particles, such as bacteria or active colloids, inside a droplet gives rise to nontrivial shape dynamics and droplet motility. To understand this behavior, we derive an asymptotic solution for the fluid flow…

Soft Condensed Matter · Physics 2025-03-19 Sho Kawakami , Petia M. Vlahovska

Deformable microchannels emulate a key characteristic of soft biological systems and flexible engineering devices: the flow-induced deformation of the conduit due to slow viscous flow within. Elucidating the two-way coupling between…

Fluid Dynamics · Physics 2026-01-14 Anxu Huang , Shrihari D. Pande , Jie Feng , Ivan C. Christov