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We report on efficient surface-enhanced Raman spectroscopy (SERS) supporting substrates, which are based on DNA-assisted lithography (DALI) and a layered configuration of materials. In detail, we used nanoscopic DNA origami bowtie templates…

Materials Science · Physics 2023-04-25 Kabusure M. Kabusure , Petteri Piskunen , Jiaqi Yang , Veikko Linko , Tommi K. Hakala

Programmable folding of elastic sheets typically relies on predefined flexible creases or active materials-enabled hinges, which lack intrinsic bistability and limit reprogrammability within a single structure. Here, we present a…

Soft Condensed Matter · Physics 2026-05-05 Qun Zhang , Weicheng Huang , Amir Hajiyavand , Hyunyoung Kim , Claire Dancer , Karl Dearn , Mingchao Liu

We propose an algorithmic framework of a pluripotent structure evolving from a simple compact structure into diverse complex 3-D structures for designing the shape transformable, reconfigurable, and deployable structures and robots. Our…

Computational Engineering, Finance, and Science · Computer Science 2022-08-09 Yu-Ki Lee , Yue Hao , Zhonghua Xi , Woongbae Kim , Youngmin Park , Kyu-Jin Cho , Jyh-Ming Lien , In-Suk Choi

Currently, third-generation sequencing techniques, which allow to obtain much longer DNA reads compared to the next-generation sequencing technologies, are becoming more and more popular. There are many possibilities to combine data from…

Genomics · Quantitative Biology 2019-05-23 Wiktor Kuśmirek , Wiktor Franus , Robert Nowak

To make 3D human avatars widely available, we must be able to generate a variety of 3D virtual humans with varied identities and shapes in arbitrary poses. This task is challenging due to the diversity of clothed body shapes, their complex…

Computer Vision and Pattern Recognition · Computer Science 2022-04-14 Xu Chen , Tianjian Jiang , Jie Song , Jinlong Yang , Michael J. Black , Andreas Geiger , Otmar Hilliges

Inorganic scintillators are widely used for scientific, industrial and medical applications. The development of 3D printing with inorganic scintillators would allow fast creation of detector prototypes for registration of ionizing…

We introduce an all-optical Diffractive Deep Neural Network (D2NN) architecture that can learn to implement various functions after deep learning-based design of passive diffractive layers that work collectively. We experimentally…

Neural and Evolutionary Computing · Computer Science 2018-09-26 Xing Lin , Yair Rivenson , Nezih T. Yardimci , Muhammed Veli , Mona Jarrahi , Aydogan Ozcan

SIMD||DNA is a model of DNA strand displacement allowing parallel in-memory computation on DNA storage. We show how to simulate an arbitrary 3-symbol space-bounded Turing machine with a SIMD||DNA program, giving a more direct and efficient…

Emerging Technologies · Computer Science 2022-02-17 David Doty , Aaron Ong

Current techniques in sequencing a genome allow a service provider (e.g. a sequencing company) to have full access to the genome information, and thus the privacy of individuals regarding their lifetime secret is violated. In this paper, we…

Genomics · Quantitative Biology 2018-11-28 Ali Gholami , Mohammad Ali Maddah-Ali , Seyed Abolfazl Motahari

We have functionalized the sides of fd bacteriophage virions with oligonucleotides to induce DNA hybridization driven self-assembly of high aspect ratio filamentous particles. Potential impacts of this new structure range from an entirely…

Switchable elements are key components of dynamic technological and biological systems, enabling reversible transitions between well-defined states. Here, we present a DNA origami-based, mechanically bistable snap-through mechanism that can…

Advances in 3D printing technology now enable the precise positioning of microscopic material voxels to form complex structures. Combined with emerging multi-material capabilities and printable responsive materials, this opens new…

Soft Condensed Matter · Physics 2025-03-17 Ido Levin , Ela Sachyani , Rama Lieberman , Noa Battat , Eran Sharon , Shlomo Magdassi

Controlling the flow of excitons between organic molecules holds immense promise for various applications, including energy conversion, spectroscopy, photocatalysis, sensing, and microscopy. DNA nanotechnology has shown promise in achieving…

Sliding is one of the fundamental mechanical movements in machinery. In macroscopic systems, double-rack pinion machines employ gears to slide two linear tracks along opposite directions. In microscopic systems, kinesin-5 proteins crosslink…

Biological Physics · Physics 2021-05-04 Maximilian J. Urban , Steffen Both , Chao Zhou , Anton Kuzyk , Klas Lindfors , Thomas Weiss , Na Liu

RNA is a fundamental class of biomolecules that mediate a large variety of molecular processes within the cell. Computational algorithms can be of great help in the understanding of RNA structure-function relationship. One of the main…

Biomolecules · Quantitative Biology 2015-02-20 Sandro Bottaro , Francesco Di Palma , Giovanni Bussi

GenoM is an approach to develop robotic software components, which can be controlled, and assembled to build complex applications. Its latest version GenoM3, provides a template mechanism which is versatile enough to deploy components for…

Robotics · Computer Science 2018-07-27 Mohammed Foughali , Félix Ingrand , Anthony Mallet

Self-supervised learning methods have witnessed a recent surge of interest after proving successful in multiple application fields. In this work, we leverage these techniques, and we propose 3D versions for five different self-supervised…

Computer Vision and Pattern Recognition · Computer Science 2020-11-03 Aiham Taleb , Winfried Loetzsch , Noel Danz , Julius Severin , Thomas Gaertner , Benjamin Bergner , Christoph Lippert

Gene assembly is an important step in functional analysis of shotgun metagenomic data. Nonetheless, strain aware assembly remains a challenging task, as current assembly tools often fail to distinguish among strain variants or require…

Quantitative Methods · Quantitative Biology 2015-10-15 I. Gregor , A. Schönhuth , A. C. McHardy

We present a theoretical discussion of a self-assembly scheme which makes it possible to use DNA to uniquely encode the composition and structure of micro- and nanoparticle clusters. These anisotropic DNA-decorated clusters can be further…

Soft Condensed Matter · Physics 2009-11-11 Nicholas A. Licata , Alexei V. Tkachenko

The diversity and heterogeneity of biomarkers has made the development of general methods for single-step quantification of analytes difficult. For individual biomarkers, electrochemical methods that detect a conformational change in an…

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