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DNA-coated particles are promising as building blocks for functional and finite-sized assemblies because they can be programmed with orthogonal interactions owing to the sequence-specific hybridization of DNA strands. To fully exploit this…

Soft Condensed Matter · Physics 2026-04-17 T. C. M. Stevens , A. van der Sluis , I. K. Voets , P. G. Moerman

Three-dimensional (3D) nano-printing via two-photon polymerization offers unparalleled design flexibility and precision, thereby enabling rapid prototyping of advanced micro-optical elements and systems, including hybrid achromats,…

Optics · Physics 2026-02-25 Florian Lux , Aybuke Calikoglu , Çağlar Ataman

Summary: Biospectrogam is an open-source software for the spectral analysis of DNA and protein sequences. The software can fetch (from NCBI server), import and manage biological data. One can analyze the data using Digital Signal Processing…

Quantitative Methods · Quantitative Biology 2012-10-05 Naman Turakhia , Nilay Chheda , Manish K. Gupta , Ruchin Shah , Jigar Raisinghani

Fabricating nanocavities in which optically-active single quantum emitters are precisely positioned, is crucial for building nanophotonic devices. Here we show that self-assembly based on robust DNA-origami constructs can precisely position…

The emerging field of hybrid DNA - protein nanotechnology brings with it the potential for many novel materials which combine the addressability of DNA nanotechnology with versatility of protein interactions. However, the design and…

Biomolecules · Quantitative Biology 2020-09-22 Jonah Procyk , Erik Poppleton , Petr Šulc

TomoSAM has been developed to integrate the cutting-edge Segment Anything Model (SAM) into 3D Slicer, a highly capable software platform used for 3D image processing and visualization. SAM is a promptable deep learning model that is able to…

Computer Vision and Pattern Recognition · Computer Science 2023-06-16 Federico Semeraro , Alexandre Quintart , Sergio Fraile Izquierdo , Joseph C. Ferguson

Surgical planning and training based on machine learning requires a large amount of 3D anatomical models reconstructed from medical imaging, which is currently one of the major bottlenecks. Obtaining these data from real patients and during…

Computer Vision and Pattern Recognition · Computer Science 2025-11-25 Ann-Sophia Müller , Moonkwang Jeong , Meng Zhang , Jiyuan Tian , Arkadiusz Miernik , Stefanie Speidel , Tian Qiu

With the rising popularity of Augmented and Virtual Reality, there is a need for representing humans as virtual avatars in various application domains ranging from remote telepresence, games to medical applications. Besides explicitly…

Computer Vision and Pattern Recognition · Computer Science 2017-10-31 Travis Gesslein , Daniel Scherer , Jens Grubert

In this study, deoxyribonucleic acid (DNA) from bananas was extracted and functionalized and used for the first time as a homeotropic alignment layer for liquid crystals (LCs). Our research was aimed at extracting and investigating DNA from…

Soft Condensed Matter · Physics 2025-04-15 Rafał Węgłowski , Anna Spadło , Dorota Węgłowska

We present a novel approach and database which combines the inexpensive generation of 3D object models via monocular or RGB-D camera images with 3D printing and a state of the art object tracking algorithm. Unlike recent efforts towards the…

Training and testing supervised object detection models require a large collection of images with ground truth labels. Labels define object classes in the image, as well as their locations, shape, and possibly other information such as…

Computer Vision and Pattern Recognition · Computer Science 2022-07-26 John Rachwan , Charbel Zalaket

Genetic engineering of cells has a range of applications in treating incurable diseases. Plasmid DNA is a popular choice of nucleic acid for cell engineering due to its low cost and stability. However, plasmid DNA must survive the…

Biological Physics · Physics 2025-10-06 Leyla Akh , Apresio K. Fajrial , Benjamin Seelbinder , Xin Xu , Wei Tan , Jill Slansky , Corey P. Neu , Xiaoyun Ding

Surface-enhanced Raman scattering (SERS) provides critical insights into analyte structure, dynamic processes, and intermolecular interactions at the single-molecule level. By exploiting the hotspot formation in the vicinity of plasmonic…

3D printing enables the fabrication of complex architectures by automating long sequences of additive steps. The increasing sophistication of printers, materials, and generative design promises to make geometric complexity a non-issue in…

Computational Engineering, Finance, and Science · Computer Science 2018-05-30 Matthew K. Gelber , Greg Hurst , Rohit Bhargava

Several technological limitations of traditional silicon based computing are leading towards the paradigm shift, from silicon to carbon, in computational world. Among the unconventional modes of computing evolved in past several decades,…

Biomolecules · Quantitative Biology 2020-10-02 Mandrita Mondal , Kumar S. Ray

DNA nanostar (DNAns) hydrogels are promising materials for in vivo applications, including tissue regeneration and drug and antibody delivery. However, a systematic and quantitative understanding of the design principles controlling their…

Domain-Driven Design (DDD) is a key framework for developing customer-oriented software, focusing on the precise modeling of an application's domain. Traditionally, metamodels that describe these domains are created manually by system…

Software Engineering · Computer Science 2026-01-30 Götz-Henrik Wiegand , Filip Stepniak , Patrick Baier

Optical imaging technologies are central to discovery in the life and physical sciences, yet their impact depends on how readily they can be built, adapted, and sustained across laboratories. Digital fabrication, including desktop 3D…

Over the past years, the ever-growing trend on data storage demand, more specifically for "cold" data (rarely accessed data), has motivated research for alternative systems of data storage. Because of its biochemical characteristics,…

Machine Learning · Computer Science 2022-03-21 Xavier Pic , Marc Antonini

Virtual microscopy includes digitisation of histology slides and the use of computer technologies for complex investigation of diseases such as cancer. However, automated image analysis, or website publishing of such digital images, is…

Image and Video Processing · Electrical Eng. & Systems 2020-08-19 Matloob Khushi , Georgina Edwards , Diego Alonso de Marcos , Jane E Carpenter , J Dinny Graham , Christine L Clarke