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We describe the first DNA-based storage architecture that enables random access to data blocks and rewriting of information stored at arbitrary locations within the blocks. The newly developed architecture overcomes drawbacks of existing…

Information Theory · Computer Science 2015-05-12 S. M. Hossein Tabatabaei Yazdi , Yongbo Yuan , Jian Ma , Huimin Zhao , Olgica Milenkovic

Plasmonic nanopores combine nanofluidic confinement with electromagnetic field enhancement, enabling optical interrogation of single molecules in sub-wavelength volumes. Yet, direct optical readout within these metallic geometries has…

Computational RNA design tasks are often posed as inverse problems, where sequences are designed based on adopting a single desired secondary structure without considering 3D conformational diversity. We introduce gRNAde, a geometric RNA…

The DNA sequencing is the process of identifying the exact order of nucleotides within a given DNA molecule. The new portable and relatively inexpensive DNA sequencers, such as Oxford Nanopore MinION, have the potential to move DNA…

Computational Engineering, Finance, and Science · Computer Science 2019-01-09 Steven Y. Ko , Lauren Sassoubre , Jaroslaw Zola

The DNA origami technique has empowered a new paradigm in plasmonics for manipulating light and matter at the nanoscale. This interdisciplinary field has witnessed vigorous growth, outlining a viable route to construct advanced plasmonic…

Applied Physics · Physics 2021-05-06 Chao Zhou , Ling Xin , Xiaoyang Duan , Maximilian J. Urban , Na Liu

The field of DNA nanotechnology has made it possible to assemble, with high yields, different structures that have actionable properties. For example, researchers have created components that can be actuated. An exciting next step is to…

Machine Learning · Computer Science 2021-02-01 Emma Benjaminson , Rebecca E. Taylor , Matthew Travers

Label-free tomographic microscopy offers a compelling means to visualize three-dimensional (3D) refractive index (RI) distributions from two-dimensional (2D) intensity measurements. However, limited forward-model accuracy and the ill-posed…

Optics · Physics 2025-02-27 Delong Yang , Shaohui Zhang , Jiasong Sun , Chao Zuo , Qun Hao

The current technological development allows us to carry out tasks that some time ago were unthinkable if not impossible, digital image processing has been one of the major constants of development today, taking into account that its…

Image and Video Processing · Electrical Eng. & Systems 2022-08-30 Benjamin Andres Huerfano Zapata

We introduce OmniPrint, a synthetic data generator of isolated printed characters, geared toward machine learning research. It draws inspiration from famous datasets such as MNIST, SVHN and Omniglot, but offers the capability of generating…

Computer Vision and Pattern Recognition · Computer Science 2022-01-19 Haozhe Sun , Wei-Wei Tu , Isabelle Guyon

Structural and functional information encoded in DNA combined with unique properties of nanomaterials could be of use for the construction of novel biocomputational circuits and intelligent biomedical nanodevices. However, at present their…

Materials Science · Physics 2013-07-16 Jun Zhang , Cuong Cao , Xinlong Xu , Chihao Liow , Shuzhou Li , Ping-Heng Tan , Qihua Xiong

Many research directions in machine learning, particularly in deep learning, involve complex, multi-stage experiments, commonly involving state-mutating operations acting on models along multiple paths of execution. Although machine…

Software Engineering · Computer Science 2020-06-16 Michela Paganini , Jessica Zosa Forde

This paper presents a novel DNA sequences alignment method based on inverted index. Now most large scale information retrieval system are all use inverted index as the basic data structure. But its application in DNA sequence alignment is…

Genomics · Quantitative Biology 2013-07-02 Wang Liang , Zhao KaiYong

Current self-supervised learning methods for 3D medical imaging rely on simple pretext formulations and organ- or modality-specific datasets, limiting their generalizability and scalability. We present 3DINO, a cutting-edge SSL method…

Image and Video Processing · Electrical Eng. & Systems 2025-01-22 Tony Xu , Sepehr Hosseini , Chris Anderson , Anthony Rinaldi , Rahul G. Krishnan , Anne L. Martel , Maged Goubran

This paper presents a novel decoder-based approach for generating manufacturable 3D structures optimized for additive manufacturing. We introduce a deep learning framework that decodes latent representations into geometrically valid,…

Computer Vision and Pattern Recognition · Computer Science 2026-01-14 Abhishek Kumar

Three-dimensional (3D) printing of bioelectronics offers a versatile platform for fabricating personalized and structurally integrated electronic systems within biological scaffolds. Biodegradable electronics, which naturally dissolve after…

Multidimensional scaling of gene sequence data has long played a vital role in analysing gene sequence data to identify clusters and patterns. However the computation complexities and memory requirements of state-of-the-art dimensional…

Artificial Intelligence · Computer Science 2021-04-20 Pulasthi Wickramasinghe , Geoffrey Fox

Dual numbers are a well-established tool for computing derivatives and constitute the basis of forward-mode automatic differentiation. While the theoretical framework for computing derivatives of arbitrary order is well understood,…

Numerical Analysis · Mathematics 2026-02-06 F. Peñuñuri , K. B. Cantún-Avila , R. Peón-Escalante

As an optical machine learning framework, Diffractive Deep Neural Networks (D2NN) take advantage of data-driven training methods used in deep learning to devise light-matter interaction in 3D for performing a desired statistical inference…

Image and Video Processing · Electrical Eng. & Systems 2020-07-08 Deniz Mengu , Yifan Zhao , Nezih T. Yardimci , Yair Rivenson , Mona Jarrahi , Aydogan Ozcan

Synthesis of DNA molecules offers unprecedented advances in storage technology. Yet, the microscopic world in which these molecules reside induces error patterns that are fundamentally different from their digital counterparts. Hence, to…

Information Theory · Computer Science 2017-08-08 Netanel Raviv , Moshe Schwartz , Eitan Yaakobi

DNA Polymerase is an enzyme that participates in the process of DNA replication. In general, forward DNA polymerase moves along the template strand in a 3'-5' direction, and the daughter strand is formed in a 5'-3' direction. This paper…

Biomolecules · Quantitative Biology 2014-09-19 Penghui Shi
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