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Automated International Classification of Diseases (ICD) coding assigns standardized diagnosis and procedure codes to clinical records, playing a critical role in healthcare systems. However, existing methods face challenges such as…

Computation and Language · Computer Science 2025-11-12 Mucheng Ren , He Chen , Yuchen Yan , Danqing Hu , Jun Xu , Xian Zeng

Process Mining has recently gained popularity in healthcare due to its potential to provide a transparent, objective and data-based view on processes. Conformance checking is a sub-discipline of process mining that has the potential to…

Artificial Intelligence · Computer Science 2020-10-23 An Nguyen , Wenyu Zhang , Leo Schwinn , Bjoern Eskofier

Each year, the lack of efficient data standardization and interoperability in cancer care contributes to the severe lack of timely and effective diagnosis, while constantly adding to the burden of cost, with cancer costs nationally reaching…

Machine Learning · Computer Science 2024-10-29 Aarsh Shekhar , Mincheol Kim

Identifying relationships between molecular variations and their clinical presentations has been challenged by the heterogeneous causes of a disease. It is imperative to unveil the relationship between the high dimensional molecular…

Methodology · Statistics 2021-09-02 Wennan Chang , Changlin Wan , Yong Zang , Chi Zhang , Sha Cao

ICD(International Classification of Diseases) coding involves assigning ICD codes to patients visit based on their medical notes. Considering ICD coding as a multi-label text classification task, researchers have developed sophisticated…

Computation and Language · Computer Science 2024-10-21 Bin Zhang , Junli Wang

Evaluating the clinical similarities between pairwise patients is a fundamental problem in healthcare informatics. A proper patient similarity measure enables various downstream applications, such as cohort study and treatment comparative…

Machine Learning · Statistics 2019-02-12 Zihao Zhu , Changchang Yin , Buyue Qian , Yu Cheng , Jishang Wei , Fei Wang

In many domains such as medicine, training data is in short supply. In such cases, external knowledge is often helpful in building predictive models. We propose a novel method to incorporate publicly available domain expertise to build…

Machine Learning · Computer Science 2020-06-03 Yun Liu , Kun-Ta Chuang , Fu-Wen Liang , Huey-Jen Su , Collin M. Stultz , John V. Guttag

The Imaging Data Commons (IDC) is a cloud-based database that provides researchers with open access to cancer imaging data, with the goal of facilitating collaboration. However, cohort discovery within the IDC database has a significant…

Machine Learning · Computer Science 2023-11-28 Pranav Kulkarni , Adway Kanhere , Paul H. Yi , Vishwa S. Parekh

Outcome prediction from clinical text can prevent doctors from overlooking possible risks and help hospitals to plan capacities. We simulate patients at admission time, when decision support can be especially valuable, and contribute a…

Computation and Language · Computer Science 2021-02-09 Betty van Aken , Jens-Michalis Papaioannou , Manuel Mayrdorfer , Klemens Budde , Felix A. Gers , Alexander Löser

In this paper, we propose a novel method based on character sequence-to-sequence models to correct documents already processed with Optical Character Recognition (OCR) systems. The main contribution of this paper is a set of strategies to…

Computation and Language · Computer Science 2022-01-26 Juan Ramirez-Orta , Eduardo Xamena , Ana Maguitman , Evangelos Milios , Axel J. Soto

Information extraction from textual documents such as hospital records and healthrelated user discussions has become a topic of intense interest. The task of medical concept coding is to map a variable length text to medical concepts and…

Computation and Language · Computer Science 2018-05-03 Elena Tutubalina , Zulfat Miftahutdinov

Multiview clustering (MVC) segregates data samples into meaningful clusters by synthesizing information across multiple views. Moreover, deep learning-based methods have demonstrated their strong feature learning capabilities in MVC…

Machine Learning · Computer Science 2024-03-22 Hao Yang , Hua Mao , Wai Lok Woo , Jie Chen , Xi Peng

Background: The problem of predicting whether a drug combination of arbitrary orders is likely to induce adverse drug reactions is considered in this manuscript. Methods: Novel kernels over drug combinations of arbitrary orders are…

Machine Learning · Computer Science 2019-02-26 Wen-Hao Chiang , Li Shen , Lang Li , Xia Ning

Many modern sequence alignment tools implement fast string matching using the space efficient data structure called FM-index. The succinct nature of this data structure presents unique challenges for the algorithm designers. In this paper,…

Data Structures and Algorithms · Computer Science 2019-09-04 Roman Snytsar

Clinical trial matching is a key process in health delivery and discovery. In practice, it is plagued by overwhelming unstructured data and unscalable manual processing. In this paper, we conduct a systematic study on scaling clinical trial…

The seriation problem seeks to reorder a set of elements given pairwise similarity information, so that elements with higher similarity are closer in the resulting sequence. When a global ordering consistent with the similarity information…

Optimization and Control · Mathematics 2018-06-05 Antoine Recanati , Nicolas Servant , Jean-Philippe Vert , Alexandre d'Aspremont

BACKGROUND: The amount of biomedical literature is rapidly growing and it is becoming increasingly difficult to keep manually curated knowledge bases and ontologies up-to-date. In this study we applied the word2vec deep learning toolkit to…

Computation and Language · Computer Science 2015-02-13 Jose Antonio Miñarro-Giménez , Oscar Marín-Alonso , Matthias Samwald

One of the ubiquitous representation of long DNA sequence is dividing it into shorter k-mer components. Unfortunately, the straightforward vector encoding of k-mer as a one-hot vector is vulnerable to the curse of dimensionality. Worse yet,…

Quantitative Methods · Quantitative Biology 2017-01-24 Patrick Ng

Machine learning-based multi-label medical text classifications can be used to enhance the understanding of the human body and aid the need for patient care. We present a broad study on clinical natural language processing techniques to…

Information Retrieval · Computer Science 2020-04-02 Vithya Yogarajan , Jacob Montiel , Tony Smith , Bernhard Pfahringer

While the ICD code assignment problem has been widely studied, most works have focused on post-discharge document classification. Models for early forecasting of this information could be used for identifying health risks, suggesting…

Machine Learning · Computer Science 2025-08-18 Cindy Shih-Ting Huang , Clarence Boon Liang Ng , Marek Rei