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Objective. Natural language processing methods for medical auto-coding, or automatic generation of medical billing codes from electronic health records, generally assign each code independently of the others. They may thus assign codes for…

Computation and Language · Computer Science 2015-10-19 Michael Subotin , Anthony R. Davis

When estimating causal effects using observational data, it is desirable to replicate a randomized experiment as closely as possible by obtaining treated and control groups with similar covariate distributions. This goal can often be…

Methodology · Statistics 2010-10-28 Elizabeth A. Stuart

One primary goal of precision medicine is to estimate the individualized treatment rules (ITRs) that optimize patients' health outcomes based on individual characteristics. Health studies with multiple treatments are commonly seen in…

Methodology · Statistics 2025-05-07 Xuqiao Li , Qiuyan Zhou , Ying Wu , Ying Yan

Word embeddings are a popular approach to unsupervised learning of word relationships that are widely used in natural language processing. In this article, we present a new set of embeddings for medical concepts learned using an extremely…

Computation and Language · Computer Science 2019-08-21 Andrew L. Beam , Benjamin Kompa , Allen Schmaltz , Inbar Fried , Griffin Weber , Nathan P. Palmer , Xu Shi , Tianxi Cai , Isaac S. Kohane

Laboratory test results are an important and generally high dimensional component of a patient's Electronic Health Record (EHR). We train embedding representations (via Word2Vec and GloVe) for LOINC codes of laboratory tests from the EHRs…

Machine Learning · Computer Science 2019-08-02 Lorenzo A. Rossi , Chad Shawber , Janet Munu , Finly Zachariah

Clinical notes are unstructured text generated by clinicians during patient encounters. Clinical notes are usually accompanied by a set of metadata codes from the International Classification of Diseases(ICD). ICD code is an important code…

Artificial Intelligence · Computer Science 2021-11-12 Tak-Sung Heo , Yongmin Yoo , Yeongjoon Park , Byeong-Cheol Jo , Kyungsun Kim

The International Classification of Diseases (ICD) serves as a definitive medical classification system encompassing a wide range of diseases and conditions. The primary objective of ICD indexing is to allocate a subset of ICD codes to a…

Computation and Language · Computer Science 2024-05-30 Xindi Wang , Robert E. Mercer , Frank Rudzicz

In this work, we propose a novel problem formulation for de-identification of unstructured clinical text. We formulate the de-identification problem as a sequence to sequence learning problem instead of a token classification problem. Our…

Computation and Language · Computer Science 2021-09-13 Md Monowar Anjum , Noman Mohammed , Xiaoqian Jiang

Automatic ICD coding is defined as assigning disease codes to electronic medical records (EMRs). Existing methods usually apply label attention with code representations to match related text snippets. Unlike these works that model the…

Computation and Language · Computer Science 2022-04-01 Zheng Yuan , Chuanqi Tan , Songfang Huang

Automatic International Classification of Diseases (ICD) coding is defined as a kind of text multi-label classification problem, which is difficult because the number of labels is very large and the distribution of labels is unbalanced. The…

Computation and Language · Computer Science 2021-06-21 Yifan Wu , Min Zeng , Ying Yu , Min Li

Randomized clinical trials (RCTs) are ideal for estimating causal effects, because the distributions of background covariates are similar in expectation across treatment groups. When estimating causal effects using observational data,…

Methodology · Statistics 2019-02-27 Anthony D. Scotina , Roee Gutman

This paper investigates an efficient and practical information reconciliation method in the case where two parties have access to correlated continuous random variables. We show that reconciliation is a special case of channel coding and…

Information Theory · Computer Science 2007-07-13 Matthieu Bloch , Andrew Thangaraj , Steven W. McLaughlin

Matching cancer patients to clinical trials is essential for advancing treatment and patient care. However, the inconsistent format of medical free text documents and complex trial eligibility criteria make this process extremely…

In observational studies of treatment effects, matched samples are created so treated and control groups are similar in terms of observable covariates. Traditionally such matched samples consist of matched pairs. If a pair match fails to…

Methodology · Statistics 2014-10-22 Luke Keele , Sam Pimentel , Frank Yoon

For large libraries of small molecules, exhaustive combinatorial chemical screens become infeasible to perform when considering a range of disease models, assay conditions, and dose ranges. Deep learning models have achieved state of the…

Recurrent claims present a major challenge for automated fact-checking systems designed to combat misinformation, especially in multilingual settings. While tasks such as claim matching and fact-checked claim retrieval aim to address this…

Computation and Language · Computer Science 2026-04-16 Rrubaa Panchendrarajan , Arkaitz Zubiaga

Automatic coding of International Classification of Diseases (ICD) is a multi-label text categorization task that involves extracting disease or procedure codes from clinical notes. Despite the application of state-of-the-art natural…

Machine Learning · Computer Science 2023-10-17 Chang Lu , Chandan K. Reddy , Ping Wang , Yue Ning

Accurate healthcare prediction is essential for improving patient outcomes. Existing work primarily leverages advanced frameworks like attention or graph networks to capture the intricate collaborative (CO) signals in electronic health…

Machine Learning · Computer Science 2025-04-02 Chuang Zhao , Hui Tang , Jiheng Zhang , Xiaomeng Li

In order to submit a claim to insurance companies, a doctor needs to code a patient encounter with both the diagnosis (ICDs) and procedures performed (CPTs) in an Electronic Health Record (EHR). Identifying and applying relevant procedures…

Machine Learning · Statistics 2021-12-30 Hasham Ul Haq , Rameel Ahmad , Sibt Ul Hussain

Clinical coding is a critical task in healthcare, although traditional methods for automating clinical coding may not provide sufficient explicit evidence for coders in production environments. This evidence is crucial, as medical coders…

Computation and Language · Computer Science 2025-04-08 Leonor Barreiros , Isabel Coutinho , Gonçalo M. Correia , Bruno Martins