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Drug similarity has been studied to support downstream clinical tasks such as inferring novel properties of drugs (e.g. side effects, indications, interactions) from known properties. The growing availability of new types of drug features…

Machine Learning · Computer Science 2018-05-01 Tengfei Ma , Cao Xiao , Jiayu Zhou , Fei Wang

The standardization of clinical data elements (CDEs) aims to ensure consistent and comprehensive patient information across various healthcare systems. Existing methods often falter when standardizing CDEs of varying representation and…

Information Retrieval · Computer Science 2025-05-08 Komal Gilani , Marlo Verket , Christof Peters , Michel Dumontier , Hans-Peter Brunner-La Rocca , Visara Urovi

This paper aims to provide an approach for automatic coding of physician-patient communication transcripts to improve patient-centered communication (PCC). PCC is a central part of high-quality health care. To improve PCC, dialogues between…

Computation and Language · Computer Science 2021-09-23 Gilchan Park , Julia Taylor Rayz , Cleveland G. Shields

Trace clustering has increasingly been applied to find homogenous process executions. However, current techniques have difficulties in finding a meaningful and insightful clustering of patients on the basis of healthcare data. The resulting…

Databases · Computer Science 2020-01-13 Xixi Lu , Seyed Amin Tabatabaei , Mark Hoogendoorn , Hajo A. Reijers

In medical coding, experts map unstructured clinical notes to alphanumeric codes for diagnoses and procedures. We introduce Code Like Humans: a new agentic framework for medical coding with large language models. It implements official…

Artificial Intelligence · Computer Science 2025-10-09 Andreas Motzfeldt , Joakim Edin , Casper L. Christensen , Christian Hardmeier , Lars Maaløe , Anna Rogers

Codification of free-text clinical narratives have long been recognised to be beneficial for secondary uses such as funding, insurance claim processing and research. The current scenario of assigning codes is a manual process which is very…

Computation and Language · Computer Science 2021-07-23 Rajvir Kaur , Jeewani Anupama Ginige , Oliver Obst

Following a series of high-profile drug safety disasters in recent years, many countries are redoubling their efforts to ensure the safety of licensed medical products. Large-scale observational databases such as claims databases or…

Computation · Statistics 2012-08-07 Marc A. Suchard , Shawn E. Simpson , Ivan Zorych , Patrick Ryan , David Madigan

Learning to represent free text is a core task in many clinical machine learning (ML) applications, as clinical text contains observations and plans not otherwise available for inference. State-of-the-art methods use large language models…

Computation and Language · Computer Science 2023-01-30 Lecheng Kong , Christopher King , Bradley Fritz , Yixin Chen

This paper aims at a newly raising task in visual surveillance: re-identifying people at a distance by matching body information, given several reference examples. Most of existing works solve this task by matching a reference template with…

Computer Vision and Pattern Recognition · Computer Science 2015-02-03 Yuanlu Xu , Liang Lin , Wei-Shi Zheng , Xiaobai Liu

Finding the same or similar code snippets in source code is one of fundamental activities in software maintenance. Text-based pattern matching tools such as grep is frequently used for such purpose, but making proper queries for the…

Software Engineering · Computer Science 2020-03-13 Katsuro Inoue , Yuya Miyamoto , Daniel M. German , Takashi Ishio

Matching for causal inference is a well-studied problem, but standard methods fail when the units to match are text documents: the high-dimensional and rich nature of the data renders exact matching infeasible, causes propensity scores to…

Methodology · Statistics 2019-03-15 Reagan Mozer , Luke Miratrix , Aaron Russell Kaufman , L. Jason Anastasopoulos

Players in the online ad ecosystem are struggling to acquire the user data required for precise targeting. Audience look-alike modeling has the potential to alleviate this issue, but models' performance strongly depends on quantity and…

Information Retrieval · Computer Science 2018-01-03 Simon Stiebellehner , Jun Wang , Shuai Yuan

Clinical coding is an administrative process that involves the translation of diagnostic data from episodes of care into a standard code format such as ICD10. It has many critical applications such as billing and aetiology research. The…

Like most global cancer registries, the National Cancer Registry in South Africa employs expert human coders to label pathology reports using appropriate International Classification of Disease for Oncology (ICD-O) codes spanning 42…

Machine Learning · Computer Science 2020-08-31 Waheeda Saib , David Sengeh , Gcininwe Dlamini , Elvira Singh

We study pattern matching problems on two major representations of uncertain sequences used in molecular biology: weighted sequences (also known as position weight matrices, PWM) and profiles (i.e., scoring matrices). In the simple version,…

Data Structures and Algorithms · Computer Science 2016-07-12 Tomasz Kociumaka , Solon P. Pissis , Jakub Radoszewski

The mutations of a complex systemic disease like cancer can be modeled as stuck-at faults in the Boolean system paradigm. For a class of multiple faults, the fault identification is exceptionally significant under the incomplete access of…

Systems and Control · Computer Science 2018-09-11 Anuj Deshpande , Ritwik Kumar Layek

Determining the optimal initial dose for warfarin is a critically important task. Several factors have an impact on the therapeutic dose for individual patients, such as patients' physical attributes (Age, Height, etc.), medication profile,…

Machine Learning · Computer Science 2019-03-25 Ashkan Sharabiani , Adam Bress , William Galanter , Rezvan Nazempour , Houshang Darabi

Progress in immunotherapy revolutionized the treatment landscape for advanced lung cancer, raising survival expectations beyond those that were historically anticipated with this disease. In the present study, we describe the methods for…

Applications · Statistics 2019-11-25 Lizet Sanchez , Patricia Lorenzo-Luaces , Claudia Fonte , Agustin Lage

One of the promising methods for the treatment of complex diseases such as cancer is combinational therapy. Due to the combinatorial complexity, machine learning models can be useful in this field, where significant improvements have…

Machine Learning · Computer Science 2020-01-08 Işıksu Ekşioğlu , Mehmet Tan

Personalized cancer treatments based on the molecular profile of a patient's tumor are an emerging and exciting class of treatments in oncology. As genomic tumor profiling is becoming more common, targeted treatments to specific molecular…

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