Related papers: On a Cahn--Hilliard--Darcy system for tumour growt…
Multiphase mechanical models are now commonly used to describe living tissues including tumour growth. The specific model we study here consists of two equations of mixed parabolic and hyperbolic type which extend the standard compressible…
In this paper we study a cross-diffusion system whose coefficient matrix is non-symmetric and degenerate. The system arises in the study of tissue growth with autophagy. The existence of a weak solution is established. We also investigate…
The nonlinear Brinkman-Forchheimer-extended Darcy equation is used to model some porous medium flow in chemical reactors of packed bed type. The results concerning the existence and uniqueness of a weak solution are presented for nonlinear…
We consider a macroscopic model for the growth of living tissues incorporating pressure-driven dispersal and pressure-modulated proliferation. Assuming a power-law relation between the mechanical pressure and the cell density, the model can…
A system with equation and dynamic boundary condition of Cahn-Hilliard type is considered. This system comes from a derivation performed in Liu-Wu (Arch. Ration. Mech. Anal. 233 (2019), 167--247) via an energetic variational approach.…
We derive, through the deterministic homogenization theory in thin domains, a new model consisting of Hele-Shaw equation with memory coupled with the convective Cahn-Hilliard equation. The obtained system, which models in particular tumor…
This paper investigates an optimal control problem associated with a two-dimensional multi-species Cahn-Hilliard-Keller-Segel tumor growth model, which incorporates complex biological processes such as species diffusion, chemotaxis,…
Models of tumor growth, now commonly used, present several levels of complexity, both in terms of the biomedical ingredients and the mathematical description. The simplest ones contain competition for space using purely fluid mechanical…
The Cahn--Hilliard equation is a widely used model that describes amongst others phase separation processes of binary mixtures or two-phase flows. In the recent years, different types of boundary conditions for the Cahn--Hilliard equation…
This paper deals with a parabolic-elliptic chemotaxis system with nonlinear diffusion. It was proved that there exists a solution of a Cahn-Hilliard system as an approximation of a nonlinear diffusion equation by applying an abstract theory…
We consider a general class of bulk-surface convective Cahn--Hilliard systems with dynamic boundary conditions. In contrast to classical Neumann boundary conditions, the dynamic boundary conditions of Cahn--Hilliard type allow for dynamic…
We study some properties of a multi-species degenerate Ginzburg-Landau energy and its relation to a cross-diffusion Cahn-Hilliard system. The model is motivated by multicomponent mixtures where crossdiffusion effects between the different…
We derive a class of Navier--Stokes--Cahn--Hilliard systems that models two-phase flows with mass transfer coupled to the process of chemotaxis. These thermodynamically consistent models can be seen as the natural Navier--Stokes analogues…
An asymptotic limit of a class of Cahn-Hilliard systems is investigated to obtain a general nonlinear diffusion equation. The target diffusion equation may reproduce a number of well-known model equations: Stefan problem, porous media…
A distributed optimal control problem for a phase field system which physical context is that of tumor growth is discussed. The system we are going to take into account consists of a Cahn-Hilliard equation for the phase variable (relative…
We develop a heuristic model embedding Kleiber and Murray laws to describe mass growth, metastasis and vascularization in cancer. We analyze the relevant dynamics using different evolution equations (Verhulst, Gompertz and others). Their…
The initial boundary value problem for a Cahn-Hilliard system subject to a dynamic boundary condition of Allen-Cahn type is treated. The vanishing of the surface diffusion on the dynamic boundary condition is the point of emphasis. By the…
In this paper, a two-dimensional model for the growth of multi-layer tumors is presented. The model consists of a free boundary problem for the tumor cell membrane and the tumor is supposed to grow or shrink due to cell proliferation or…
The paper deals with a phase field system of Cahn-Hilliard type. For positive viscosity coefficients, the authors prove an existence and uniqueness result and study the long time behavior of the solution by assuming the nonlinearities to be…
In this work, we investigate the population dynamics of tumor cells under therapeutic pressure. Although drug treatment initially induces a reduction in tumor burden, treatment failure frequently occurs over time due to the emergence of…