Related papers: On a Cahn--Hilliard--Darcy system for tumour growt…
Swelling media (e.g. gels, tumors) are usually described by mechanical constitutive laws (e.g. Hooke or Darcy laws). However, constitutive relations of real swelling media are not well known. Here, we take an opposite route and consider a…
We study the well-posedness of a modified degenerate Cahn-Hilliard type model for surface diffusion. With degenerate phase-dependent diffusion mobility and additional stabilizing function, this model is able to give the correct sharp…
We study a model introduced by Perthame and Vauchelet that describes the growth of a tumor governed by Brinkman's Law, which takes into account friction between the tumor cells. We adopt the viscosity solution approach to establish an…
We establish the global existence of weak solutions for a two-species cross-diffusion system, set on the 1-dimensional flat torus, in which the evolution of each species is governed by two mechanisms. The first of these is a diffusion which…
In this paper, we studied phase-space analysis of a certain mathematical model of tumor growth with an immune responses and chemotherapy therapy. Mathematical modelling of this process is viewed as a potentially powerful tool in the…
Motivated by the incompressible limit of a cell density model, we propose a free boundary tumor growth model where the pressure satisfies an obstacle problem on an evolving domain $\Omega(t)$, and the coincidence set $\Lambda(t)$ captures…
We consider a mathematical model for the evolutionary dynamics of tumour cells in vascularised tumours under chemotherapy. The model comprises a system of coupled partial integro-differential equations for the phenotypic distribution of…
The continuous dependence on the initial data and consequently the uniqueness of bounded weak solutions to a class of triangular reaction-cross-diffusion equations is shown. The class includes two-species doubly degenerate equations for…
The well-known Cahn-Hilliard equation entails mass conservation if a suitable boundary condition is prescribed. In the case when the equation is also coupled with a dynamic boundary condition, including the Laplace-Beltrami operator on the…
We study the weak solvability of a system of coupled Allen-Cahn-like equations resembling cross-diffusion which is arising as a model for the consolidation of saturated porous media. Besides using energy like estimates, we cast the special…
Models of tissue growth are now well established, in particular in relation to their applications to cancer. They describe the dynamics of cells subject to motion resulting from a pressure gradient generated by the death and birth of cells,…
Tumor growth beyond a critical size relies on the development of a functional vascular network, which ensures adequate oxygen and nutrient supply. In this work, we present a modeling framework based on an optimization-based 3D-1D coupling…
The transport of single-phase fluid mixtures in porous media is described by cross-diffusion equations for the mass densities. The equations are obtained in a thermodynamic consistent way from mass balance, Darcy's law, and the van der…
Widely used models in genetics include the Wright-Fisher diffusion and its moment dual, Kingman's coalescent. Each has a multilocus extension but under neither extension is the sampling distribution available in closed-form, and their…
We extend previous weak well-posedness results obtained in Frigeri et al. (2017) concerning a non-local variant of a diffuse interface tumor model proposed by Hawkins-Daarud et al. (2012). The model consists of a non-local Cahn--Hilliard…
We introduce a diffuse interface model describing the evolution of a mixture of two different viscous incompressible fluids of equal density. The main novelty of the present contribution consists in the fact that the effects of temperature…
We investigate a diffuse-interface model that describes the dynamics of incompressible two-phase viscous flows with surfactant. The resulting system of partial differential equations consists of a sixth-order Cahn-Hilliard equation for the…
This paper proposes a novel chaotic reaction-diffusion model of cellular tumor growth and metastasis. The model is based on the multiscale diffusion cancer-invasion model (MDCM) and formulated by introducing strong nonlinear coupling into…
In this paper, we conduct a thorough mathematical analysis of a tumor growth model with treatments. The model is a system describing the evolution of metastatic tumors and the number of cells present in a primary tumor. The former evolution…
The problem of the onset and growth of solid tumour in homogeneous tissue is regarded using an approach based on local interaction between the tumoral and the sane tissue cells. The characteristic sizes and growth rates of spherical…