Related papers: On a Cahn--Hilliard--Darcy system for tumour growt…
In this study, we model avascular tumour growth in epithelial tissue. This can help us to get a macroscopic view of the interaction between the tumour with its surrounding microenvironment and the physical changes within the tumour…
We study the continuity of weak solutions for quasilinear elliptic systems with source terms of critical growth arising from a transport-energy structure. The latter occurs frequently in connection with the first balance principles of…
Both compressible and incompressible porous medium models are used in the literature to describe the mechanical properties of living tissues. These two classes of models can be related using a stiff pressure law. In the incompressible…
In this paper we present a study of local dynamics of the growth of cancer tumor and healthy cells considering the presence of nutrients in the system. We also analyze the evolution of system if we take indirectly into account the level of…
In this paper we study the "stiff pressure limit" of the porous medium equation, where the initial density is a bounded, integrable function with a sufficient decay at infinity. Our particular model, introduced by Perthame-Quiros-Vazquez,…
A reaction-diffusion system exhibiting Turing's diffusion driven instability is considered. The equation for an activator is supplemented by unilateral terms of the type $s_{-}(x)u^{-}$, $s_{+}(x)u^{+}$ describing sources and sinks active…
A nutrient-limited model for avascular cancer growth including cell proliferation, motility and death is presented. The model qualitatively reproduces commonly observed morphologies for primary tumors, and the simulated patterns are…
We investigate the tumor boundary instability induced by nutrient consumption and supply based on a Hele-Shaw model derived from taking the incompressible limit of a cell density model. We analyze the boundary stability/instability in two…
In this paper, the authors study the distributed optimal control of a system of three evolutionary equations involving fractional powers of three selfadjoint, monotone, unbounded linear operators having compact resolvents. The system is a…
This paper treats a distributed optimal control problem for a tumor growth model of Cahn-Hilliard type including chemotaxis. The evolution of the tumor fraction is governed by a variational inequality corresponding to a double obstacle…
In this article we shall trace the historical development of tumour growth laws, which in a quantitative fashion describe the increase in tumour mass/volume over time. These models are usually formulated in terms of differential equations…
We consider a model system consisting of two reaction-diffusion equations, where one species diffuses in a volume while the other species diffuses on the surface which surrounds the volume. The two equations are coupled via a nonlinear…
A mathematical analysis of local and nonlocal phase-field models of tumor growth is presented that includes time-dependent Darcy-Forchheimer-Brinkman models of convective velocity fields and models of long-range cell interactions. A…
In this paper we study a mathematical model for the growth of nonnecrotic solid tumor. The tumor is assumed to be radially symmetric and its radius R(t) is an unknown function of time t as tumor growth, and the model is in the form of a…
A novel numerical technique has been proposed to solve a two-phase tumour growth model in one spatial dimension without needing to account for the boundary dynamics explicitly. The equivalence to the standard definition of a weak solution…
We study a quasi-incompressible Navier--Stokes/Cahn--Hilliard coupled system which describes the motion of two macroscopically immiscible incompressible viscous fluids with partial mixing in a small interfacial region and long-range…
We consider a mathematical model coupling the Cahn-Hilliard system for phase separation with an additional equation describing the diffusion process of a chemical quantity whose concentration influences the physical process. The main…
Various models of tumor growth are available in the litterature. A first class describes the evolution of the cell number density when considered as a continuous visco-elastic material with growth. A second class, describes the tumor as a…
Tumor development is an evolutionary process in which a heterogeneous population of cells with differential growth capabilities compete for resources in order to gain a proliferative advantage. What are the minimal ingredients needed to…
In this paper we propose a time discretization of a system of two parabolic equations describing diffusion-driven atom rearrangement in crystalline matter. The equations express the balances of microforces and microenergy; the two phase…