Related papers: On a Cahn--Hilliard--Darcy system for tumour growt…
We study an initial-boundary value problem (IBVP) for a coupled Cahn-Hilliard-Hele-Shaw system that models tumor growth. For large initial data with finite energy, we prove global (local resp.) existence, uniqueness, higher order spatial…
In this paper, we propose a tumor growth model to incorporate and investigate the spatial effects of autophagy. The cells are classified into two phases: normal cells and autophagic cells, whose dynamics are also coupled with the nutrients.…
The Cahn-Hilliard model with reaction terms can lead to situations in which no coarsening is taking place and, in contrast, growth and division of droplets occur which all do not grow larger than a certain size. This phenomenon has been…
Condition imposed on the nonlinear terms of a nonlinear diffusion equation with {R}obin boundary condition is the main focus of this paper. The degenerate parabolic equations, such as the {S}tefan problem, the {H}ele--{S}haw problem, the…
In this work, we present and analyze a system of PDEs, which models tumor growth by considering chemotaxis, active transport, and random effects. The stochasticity of the system is modelled by random initial data and Wiener noises that…
This paper is concerned with a phase field system of Cahn-Hilliard type that is related to a tumor growth model and consists of three equations in terms of the variables order parameter, chemical potential and nutrient concentration. This…
We study a Cahn-Hilliard-Hele-Shaw (or Cahn-Hilliard-Darcy) system for an incompressible mixture of two fluids. The relative concentration difference $\varphi$ is governed by a convective nonlocal Cahn-Hilliard equation with degenerate…
We consider a particular phase field system which physical context is that of tumor growth dynamics. The model we deal with consists of a Cahn-Hilliard type equation governing the evolution of the phase variable which takes into account the…
We investigate the dynamics of a nonlinear system modeling tumor growth with drug application. The tumor is viewed as a mixture consisting of proliferating, quiescent and dead cells as well as a nutrient in the presence of a drug. The…
We investigate avascular tumour growth as a two-phase process consisting of cells and liquid. Based on the one-dimensional continuum moving-boundary model formulated by (Byrne, King, McElwain, Preziosi, Applied Mathematics Letters, 2003,…
We investigate the evolution of tumor growth relying on a nonlinear model of partial differential equations which incorporates mechanical laws for tissue compression combined with rules for nutrients availability and drug application.…
The Cahn--Hilliard equation is a fundamental model that describes phase separation processes of binary mixtures. In recent years, several types of dynamic boundary conditions have been proposed in order to account for possible short-range…
We analyze a diffuse interface model that describes the dynamics of incompressible two-phase flows influenced by interactions with a soluble chemical substance, encompassing the chemotaxis effect, mass transport, and reactions. In the…
We consider a non-local tumour growth model of phase-field type, describing the evolution of tumour cells through proliferation in presence of a nutrient. The model consists of a coupled system, incorporating a non-local Cahn-Hilliard…
In the present work, we address a class of Cahn-Hilliard equations characterized by a nonlinear diffusive dynamics and possibly containing an additional sixth order term. This model describes the separation properties of oil-water mixtures,…
The mathematical analysis of diffuse-interface models for multiphase flows has attracted significant attention due to their ability to capture complex interfacial dynamics, including curvature effects, within a unified, energetically…
This paper investigates the existence of weak solutions to two problems set of elliptic equations in adjoining domains, with Beavers--Joseph--Saffman and regularized Butler--Volmer boundary conditions being prescribed on the common…
In this work, we present a coupled 3D-1D model of solid tumor growth within a dynamically changing vascular network to facilitate realistic simulations of angiogenesis. Additionally, the model includes erosion of the extracellular matrix,…
In this paper we study singular limits of congestion-averse growth models, connecting different models describing the effect of congestion. These models arise in particular in the context of tissue growth. The main ingredient of our…
Mechanical models for tumor growth have been used extensively in recent years for the analysis of medical observations and for the prediction of cancer evolution based on imaging analysis. This work deals with the numerical approximation of…