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Computed Tomography (CT) imaging, while essential for diagnostics, exposes patients to ionizing radiation. To accurately quantify radiation dosage, this study introduces MIDSX, a specialized open-source Monte Carlo (MC) photon transport…

Medical Physics · Physics 2023-11-29 John Meneghini

Energetic ions lose their energy in tissue mainly by ionising its molecules. This produces secondary electrons which transport this energy radially away from the ion path. The ranges of most of these electrons do not exceed a few…

Biological Physics · Physics 2017-11-07 Pablo de Vera , Eugene Surdutovich , Nigel J. Mason , Andrey V. Solov'yov

A new expression for the total K-shell ionization cross section by electron impact based on the relativistic extension of the binary encounter Bethe (RBEB) model, valid from ionization threshold up to relativistic energies, is proposed. The…

Atomic Physics · Physics 2015-05-28 J. P. Santos , M. Guerra , F. Parente

Targeted Radionuclide Therapy (TRT) is a well-established technique for cancer treatment. In this approach, radionuclides are bound to specific drugs that selectively transport them to the tumor site. Within the ISOLPHARM project, a…

Flattening filter free (FFF) beams due to their non-uniformity, are sub-optimal for larger field sizes. The purpose of this study was to investigate the incident electron beam distributions that would produce flat FFF beams without the use…

Medical Physics · Physics 2015-06-16 Sergei Zavgorodni

Objective: Research on eye lens dosimetry for radiation workers has increased after the 2012 ICRP118 update on eye lens dose limits. However, corneal dosimetry remains underexplored due to historical focus and measurement challenges. This…

Medical Physics · Physics 2025-09-26 Zahra Akbari Khanaposhtani , Hossein Rajabi

Laser-plasma accelerators can produce ultra short electron bunches in the femtosecond to picosecond duration range, resulting in high peak dose rates in comparison with clinical accelerators. This peculiar characteristic motivates their…

Understanding the spatio-temporal evolution of radiolytic species created by high-energy electrons in water underpins key applications from radiotherapy and nuclear safety to environmental processing and electron microscopy. Here, using the…

Chemical Physics · Physics 2026-01-06 Charlie Fynn Perkins , Marcus Webb , Fred J. Currell

Most virtual source models (VSM) use beam modeling, with the exception of the patient-dependent secondary collimator (jaw). Unlike other components of the treatment head, the jaw absorbs many photons generated by the bremsstrahlung, which…

Particle-based kinetic Monte Carlo simulations of neutral particles is one of the major computational bottlenecks in tokamak scrape-off layer simulations. This computational cost comes from the need to resolve individual collision events in…

Computational Engineering, Finance, and Science · Computer Science 2026-03-27 Oskar Lappi , Emil Løvbak , Thijs Steel , Giovanni Samaey

Purpose: The purpose of the present article is to propose a modified version of the D-shaped collimator used at the Univ. Hosp. of Essen for retinoblastoma treatment that reduces even further the irradiation field with the scope to reduce…

Medical Physics · Physics 2018-09-26 P. A. Mayorga , L. Brualla , W. Sauerwein , A. M. Lallena

A prototype of ion beam transport module has been developed at the Institut Pluridisciplinaire Hubert Curien (IPHC) and used as a test bed to investigate key issues related to the efficient transport of ion beams. This includes the…

Accelerator Physics · Physics 2023-03-14 F Osswald , E Traykov , T Durand , M Heine , J Michaud , J C Thomas

The low relative charge-to-mass ratio offset of 0.065% between fully ionized helium-4 and carbon-12 ions enables simultaneous acceleration in hadron therapy synchrotrons. At the same energy per mass, helium ions exhibit a stopping range…

High gradient accelerator injectors have been widely studied throughout the world-leading accelerator facilities. The demand for high frequency cavities have led the Detector, Accelerator and instrumentation laboratory (KAHVELab) in…

Background: Recently, mixed carbon-helium beams were proposed for range verification in carbon ion therapy: Helium, with three times the range of carbon, serves as an on-line range probe, and is mixed into a therapeutic carbon beam.…

Medical Physics · Physics 2025-12-17 Jennifer J. Hardt , Alexander A. Pryanichnikov , Oliver Jäkel , Joao Seco , Niklas Wahl

Radiation therapy aims to deliver the prescribed amount of dose to a tumour at the same time as sparing the surrounding tissues as much as possible. In charged particle therapy, delivering the prescribed dose is equivalent to delivering the…

Medical Physics · Physics 2018-03-05 Simona Giordanengo , Marco Donetti

Bayesian analysis is widely used in science and engineering for real-time forecasting, decision making, and to help unravel the processes that explain the observed data. These data are some deterministic and/or stochastic transformations of…

Optimization and Control · Mathematics 2020-02-24 Jiangjiang Zhang , Jasper A. Vrugt , Xiaoqing Shi , Guang Lin , Lingzao Zeng , Laosheng Wu

In this paper we investigate, with a detailed Monte-Carlo simulation based on Geant4, the novel approach [Nucl. Instrum. Methods A588 (2008) 457] to 3D imaging with photon scattering. A monochromatic and well collimated gamma beam is used…

Medical Physics · Physics 2011-09-23 M. Lenti , M. Veltri

A simulation package employing a Particle in Cell (PIC) method is developed to study the high current beam transport and the dynamics of plasmas. This package includes subroutines those are suited for various planned projects at University…

Accelerator Physics · Physics 2016-06-21 N. Joshi

Particle in cell simulations are widely used in most fields of physics to investigate known and new phenomena which cannot be directly observed or measured yet. However, the computational and time resources needed for PICs make them…