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Computational methods are the most effective tools we have besides scientific experiments to explore the properties of complex biological systems. Progress is slowing because digital silicon computers have reached their limits in terms of…

Quantum Physics · Physics 2020-04-03 Viv Kendon

Motivation: Most existing methods for DNA sequence analysis rely on accurate sequences or genotypes. However, in applications of the next-generation sequencing (NGS), accurate genotypes may not be easily obtained (e.g. multi-sample…

Genomics · Quantitative Biology 2013-03-19 Heng Li

We introduce new families of enhanced chaotic number generators in order to compute very fast long series of pseudorandom numbers. The key feature of these generators being the use of chaotic numbers themselves for sampling chaotic…

Dynamical Systems · Mathematics 2008-02-20 R. Lozi

Spiking neural networks (SNNs) represent a promising approach to developing artificial neural networks that are both energy-efficient and biologically plausible. However, applying SNNs to sequential tasks, such as text classification and…

Neural and Evolutionary Computing · Computer Science 2024-10-14 Changze Lv , Dongqi Han , Yansen Wang , Xiaoqing Zheng , Xuanjing Huang , Dongsheng Li

Wireless Sensor Networks (WSNs) have gained worldwide attention in recent years, particularly with the proliferation in Micro-Electro-Mechanical Systems (MEMS) technology which has facilitated the development of smart sensors. The paper…

Networking and Internet Architecture · Computer Science 2010-02-26 Neelam Srivastava

With rapidly increasing data, clustering algorithms are important tools for data analytics in modern research. They have been successfully applied to a wide range of domains; for instance, bioinformatics, speech recognition, and financial…

Data Structures and Algorithms · Computer Science 2015-12-01 Ka-Chun Wong

Discovering causal genetic variants from large genetic association studies poses many difficult challenges. Assessing which genetic markers are involved in determining trait status is a computationally demanding task, especially in the…

Genomics · Quantitative Biology 2015-04-09 Andrew L. Beam , Alison Motsinger-Reif , Jon Doyle

A rapid and low-cost method to sequence DNA would usher in a revolution in medicine. We propose and theoretically show the feasibility of a protocol for sequencing based on the distributions of transverse electrical currents of…

Soft Condensed Matter · Physics 2015-06-25 Johan Lagerqvist , Michael Zwolak , Massimiliano Di Ventra

Reliable spike detection and sorting, the process of assigning each detected spike to its originating neuron, is an essential step in the analysis of extracellular electrical recordings from neurons. The volume and complexity of the data…

Neurons and Cognition · Quantitative Biology 2018-09-05 Matthias H. Hennig , Cole Hurwitz , Martino Sorbaro

Metagenomics is a powerful approach to study genetic content of environmental samples that has been strongly promoted by NGS technologies. To cope with massive data involved in modern metagenomic projects, recent tools [4, 39] rely on the…

Genomics · Quantitative Biology 2016-03-17 Karel Brinda , Maciej Sykulski , Gregory Kucherov

Quantum computers are next-generation devices that hold promise to perform calculations beyond the reach of classical computers. A leading method towards achieving this goal is through quantum machine learning, especially quantum generative…

The Next Generation Networks (NGN) aims to integrate for IP-based telecom infrastructures and provide most advance & high speed emerging value added services. NGN capable to provide higher innovative services, these services will able to…

Networking and Internet Architecture · Computer Science 2011-11-10 Kamaljit I. Lakhtaria , Dhinaharan Nagamalai

Spectral clustering (SC) is one of the most popular clustering methods and often outperforms traditional clustering methods. SC uses the eigenvectors of a Laplacian matrix calculated from a similarity matrix of a dataset. SC has serious…

Machine Learning · Computer Science 2021-08-27 Kazuhisa Fujita

By all measures, wireless networking has seen explosive growth over the past decade. Fourth Generation Long Term Evolution (4G LTE) cellular technology has increased the bandwidth available for smartphones, in essence, delivering broadband…

Computers and Society · Computer Science 2021-01-06 Elisa Bertino , Daniel Bliss , Daniel Lopresti , Larry Peterson , Henning Schulzrinne

Network neuroscience is the emerging discipline concerned with investigating the complex patterns of interconnections found in neural systems, and to identify principles with which to understand them. Within this discipline, one…

Neurons and Cognition · Quantitative Biology 2017-08-29 Richard F. Betzel , Danielle S. Bassett

Over the past several years, DNA sequencing has emerged as one of the driving forces in life-sciences, paving the way for affordable and accurate whole genome sequencing. As genomes represent the entirety of an organism's hereditary…

Cryptography and Security · Computer Science 2015-02-17 Emiliano De Cristofaro

Genome sequence analysis plays a pivotal role in enabling many medical and scientific advancements in personalized medicine, outbreak tracing, and forensics. However, the analysis of genome sequencing data is currently bottlenecked by the…

Hardware Architecture · Computer Science 2021-11-04 Damla Senol Cali

The overwhelming presence of categorical/sequential data in diverse domains emphasizes the importance of sequence mining. The challenging nature of sequences proves the need for continuing research to find a more accurate and faster…

Machine Learning · Computer Science 2022-04-26 Hadi Jahanshahi , Mustafa Gokce Baydogan

DNA sequence alignment is important today as it is usually the first step in finding gene mutation, evolutionary similarities, protein structure, drug development and cancer treatment. Covid-19 is one recent example. There are many…

Genomics · Quantitative Biology 2023-06-01 Suchindra , Preetam Nagaraj