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Scientists aim to extract simplicity from observations of the complex world. An important component of this process is the exploration of data in search of trends. In practice, however, this tends to be more of an art than a science. Among…

Machine Learning · Computer Science 2021-08-11 Dalya Baron , Brice Ménard

Next Generation Sequencing (NGS) platforms and, more generally, high-throughput technologies are giving rise to an exponential growth in the size of nucleotide sequence databases. Moreover, many emerging applications of nucleotide datasets…

Databases · Computer Science 2019-10-11 Ferdinando Montecuollo , Giovannni Schmid , Roberto Tagliaferri

Recurrent neural networks (RNNs) are capable of learning features and long term dependencies from sequential and time-series data. The RNNs have a stack of non-linear units where at least one connection between units forms a directed cycle.…

Neural and Evolutionary Computing · Computer Science 2018-02-26 Hojjat Salehinejad , Sharan Sankar , Joseph Barfett , Errol Colak , Shahrokh Valaee

Recent years have witnessed a surge in the popularity of Machine Learning (ML), applied across diverse domains. However, progress is impeded by the scarcity of training data due to expensive acquisition and privacy legislation. Synthetic…

Machine Learning · Computer Science 2024-02-05 André Bauer , Simon Trapp , Michael Stenger , Robert Leppich , Samuel Kounev , Mark Leznik , Kyle Chard , Ian Foster

In the present era of technology computer has facilitated the human life up to a great extent. The speed of computation has raised to astonish level but the pace of development of other technologies which have core dependency over computers…

Emerging Technologies · Computer Science 2011-08-03 Umer Farooq , M. Aqeel Iqbal

Recurrent neural networks are used to forecast time series in finance, climate, language, and from many other domains. Reservoir computers are a particularly easily trainable form of recurrent neural network. Recently, a "next-generation"…

Machine Learning · Computer Science 2023-03-28 Sarah E. Marzen , Paul M. Riechers , James P. Crutchfield

Within the preprocessing pipeline of a Next Generation Sequencing sample, its set of Single-Base Mismatches is one of the first outcomes, together with the number of correctly aligned reads. The union of these two sets provides a 4x4 matrix…

Quantitative Methods · Quantitative Biology 2011-09-07 Marco Chierici , Giuseppe Jurman , Marco Roncador , Cesare Furlanello

Computing is a critical driving force in the development of human civilization. In recent years, we have witnessed the emergence of intelligent computing, a new computing paradigm that is reshaping traditional computing and promoting…

To uncover the genetic basis of complex disease, individuals are often measured at a large number of genetic variants (usually SNPs) across the genome. GemTools provides computationally efficient tools for modeling genetic ancestry based on…

Applications · Statistics 2011-04-07 Lambertus Klei , Brian P. Kent , Nadine Melhem , Bernie Devlin , Kathryn Roeder

Identifying promising compounds from a vast collection of feasible compounds is an important and yet challenging problem in the pharmaceutical industry. An efficient solution to this problem will help reduce the expenditure at the early…

Applications · Statistics 2009-06-09 Abhyuday Mandal , Pritam Ranjan , C. F. Jeff Wu

In the last few years, there have been several revolutions in the field of deep learning, mainly headlined by the large impact of Generative Adversarial Networks (GANs). GANs not only provide an unique architecture when defining their…

Machine Learning · Computer Science 2024-02-19 Guillermo Iglesias , Edgar Talavera , Alberto Díaz-Álvarez

In the last few years, deep learning has led to very good performance on a variety of problems, such as visual recognition, speech recognition and natural language processing. Among different types of deep neural networks, convolutional…

Computer Vision and Pattern Recognition · Computer Science 2017-10-20 Jiuxiang Gu , Zhenhua Wang , Jason Kuen , Lianyang Ma , Amir Shahroudy , Bing Shuai , Ting Liu , Xingxing Wang , Li Wang , Gang Wang , Jianfei Cai , Tsuhan Chen

In sequential decision making, neural networks (NNs) are nowadays commonly used to represent and learn the agent's policy. This area of application has implied new software quality assessment challenges that traditional validation and…

Software Engineering · Computer Science 2023-12-18 Q. Mazouni , H. Spieker , A. Gotlieb , M. Acher

Rapid advances in human genomics are enabling researchers to gain a better understanding of the role of the genome in our health and well-being, stimulating hope for more effective and cost efficient healthcare. However, this also prompts a…

Cryptography and Security · Computer Science 2018-08-20 Alexandros Mittos , Bradley Malin , Emiliano De Cristofaro

Edge Computing is a promising technology to provide new capabilities in technological fields that require instantaneous data processing. Researchers in areas such as machine and deep learning use extensively edge and cloud computing for…

We present a performant, general-purpose gradient-guided nested sampling algorithm, ${\tt GGNS}$, combining the state of the art in differentiable programming, Hamiltonian slice sampling, clustering, mode separation, dynamic nested…

Machine Learning · Computer Science 2023-12-08 Pablo Lemos , Nikolay Malkin , Will Handley , Yoshua Bengio , Yashar Hezaveh , Laurence Perreault-Levasseur

Many evolutionary algorithms (EAs) take advantage of parallel evaluation of candidates. However, if evaluation times vary significantly, many worker nodes (i.e.,\ compute clients) are idle much of the time, waiting for the next generation…

Neural and Evolutionary Computing · Computer Science 2024-01-02 Jason Liang , Hormoz Shahrzad , Risto Miikkulainen

Neurotechnology has made great strides in the last 20 years. However, we still have a long way to go to commercialize many of these technologies as we lack a unified framework to study cyber-neural systems (CNS) that bring the hardware,…

Optimization and Control · Mathematics 2021-12-17 Emily Reed , Sarthak Chatterjee , Guilherme Ramos , Paul Bogdan , Sérgio Pequito

This paper presents a comprehensive study of Retrieval-Augmented Generation (RAG), tracing its evolution from foundational concepts to the current state of the art. RAG combines retrieval mechanisms with generative language models to…

Computation and Language · Computer Science 2024-10-18 Shailja Gupta , Rajesh Ranjan , Surya Narayan Singh

State-of-the-art solutions in the areas of "Language Modelling & Generating Text", "Speech Recognition", "Generating Image Descriptions" or "Video Tagging" have been using Recurrent Neural Networks as the foundation for their approaches.…

Machine Learning · Computer Science 2019-12-13 Robin M. Schmidt