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Pre-training general-purpose visual features with convolutional neural networks without relying on annotations is a challenging and important task. Most recent efforts in unsupervised feature learning have focused on either small or highly…

Computer Vision and Pattern Recognition · Computer Science 2019-08-14 Mathilde Caron , Piotr Bojanowski , Julien Mairal , Armand Joulin

Cryo-Electron Tomography (cryo-ET) is a 3D imaging technology that enables the visualization of subcellular structures in situ at near-atomic resolution. Cellular cryo-ET images help in resolving the structures of macromolecules and…

Quantitative Methods · Quantitative Biology 2021-11-18 Hmrishav Bandyopadhyay , Zihao Deng , Leiting Ding , Sinuo Liu , Mostofa Rafid Uddin , Xiangrui Zeng , Sima Behpour , Min Xu

I present a strategy for unsupervised manifold learning on local atomic environments in molecular simulations based on simple rotation- and permutation-invariant three-body features. These features are highly descriptive, generalize to…

Materials Science · Physics 2023-01-03 Wesley F. Reinhart

Single particle cryo-electron microscopy has become a critical tool in structural biology over the last decade, able to achieve atomic scale resolution in three dimensional models from hundreds of thousands of (noisy) two-dimensional…

Numerical Analysis · Mathematics 2023-07-19 Aaditya V. Rangan , Leslie Greengard

Machine Learning (ML) is increasingly being used for computer aided diagnosis of brain related disorders based on structural magnetic resonance imaging (MRI) data. Most of such work employs biologically and medically meaningful hand-crafted…

Machine Learning · Computer Science 2018-05-04 Ayush Jaiswal , Dong Guo , Cauligi S. Raghavendra , Paul Thompson

In many machine learning applications, labeling datasets can be an arduous and time-consuming task. Although research has shown that semi-supervised learning techniques can achieve high accuracy with very few labels within the field of…

Computer Vision and Pattern Recognition · Computer Science 2023-06-07 Evelyn J. Mannix , Howard D. Bondell

Different tasks in the computational pipeline of single-particle cryo-electron microscopy (cryo-EM) require enhancing the quality of the highly noisy raw images. To this end, we develop an efficient algorithm for signal enhancement of…

Image and Video Processing · Electrical Eng. & Systems 2022-12-06 Guy Sharon , Yoel Shkolnisky , Tamir Bendory

The task of labeling data for training deep neural networks is daunting and tedious, requiring millions of labels to achieve the current state-of-the-art results. Such reliance on large amounts of labeled data can be relaxed by exploiting…

Machine Learning · Computer Science 2016-02-17 Aysegul Dundar , Jonghoon Jin , Eugenio Culurciello

Autoencoding is a popular method in representation learning. Conventional autoencoders employ symmetric encoding-decoding procedures and a simple Euclidean latent space to detect hidden low-dimensional structures in an unsupervised way.…

Machine Learning · Computer Science 2024-10-07 Stefan C. Schonsheck , Scott Mahan , Timo Klock , Alexander Cloninger , Rongjie Lai

The clustering of unlabeled raw images is a daunting task, which has recently been approached with some success by deep learning methods. Here we propose an unsupervised clustering framework, which learns a deep neural network in an…

Computer Vision and Pattern Recognition · Computer Science 2020-12-16 Guy Shiran , Daphna Weinshall

In this paper, we focus on unsupervised representation learning for clustering of images. Recent advances in deep clustering and unsupervised representation learning are based on the idea that different views of an input image (generated…

Computer Vision and Pattern Recognition · Computer Science 2022-04-26 Aniket Anand Deshmukh , Jayanth Reddy Regatti , Eren Manavoglu , Urun Dogan

Semi-supervised learning utilizes insights from unlabeled data to improve model generalization, thereby reducing reliance on large labeled datasets. Most existing studies focus on limited samples and fail to capture the overall data…

Computer Vision and Pattern Recognition · Computer Science 2025-03-13 Xiuzhen Guo , Lianyuan Yu , Ji Shi , Na Lei , Hongxiao Wang

Spectral Embedding (SE) has often been used to map data points from non-linear manifolds to linear subspaces for the purpose of classification and clustering. Despite significant advantages, the subspace structure of data in the original…

Computer Vision and Pattern Recognition · Computer Science 2023-05-16 Hira Yaseen , Arif Mahmood

We consider joint estimation of multiple graphical models arising from heterogeneous and high-dimensional observations. Unlike most previous approaches which assume that the cluster structure is given in advance, an appealing feature of our…

Machine Learning · Statistics 2018-01-16 Botao Hao , Will Wei Sun , Yufeng Liu , Guang Cheng

Recent developed deep unsupervised methods allow us to jointly learn representation and cluster unlabelled data. These deep clustering methods mainly focus on the correlation among samples, e.g., selecting high precision pairs to gradually…

Computer Vision and Pattern Recognition · Computer Science 2019-08-13 Jianlong Wu , Keyu Long , Fei Wang , Chen Qian , Cheng Li , Zhouchen Lin , Hongbin Zha

Cryo-electron microscopy (cryo-EM) has become a major experimental technique to determine the structures of large protein complexes and molecular assemblies, as evidenced by the 2017 Nobel Prize. Although cryo-EM has been drastically…

Biomolecules · Quantitative Biology 2021-06-01 Dong Si , Andrew Nakamura , Runbang Tang , Haowen Guan , Jie Hou , Ammaar Firozi , Renzhi Cao , Kyle Hippe , Minglei Zhao

Cryo-electron microscopy (cryo-EM) studies using single particle reconstruction is extensively used to reveal structural information of macromolecular complexes. Aiming at the highest achievable resolution, state of the art electron…

Computer Vision and Pattern Recognition · Computer Science 2020-05-04 Ramin Norousi , Stephan Wickles , Thomas Becker , Roland Beckmann , Volker J. Schmid , Achim Tresch

We consider the problem of analyzing the structure of spectroscopic cubes using unsupervised machine learning techniques. We propose representing the target's signal as a homogeneous set of volumes through an iterative algorithm that…

Instrumentation and Methods for Astrophysics · Physics 2018-06-15 Mauricio Araya , Marcelo Mendoza , Mauricio Solar , Diego Mardones , Amelia Bayo

Rock mass classification systems are crucial for assessing stability and risk in underground construction globally and guiding support and excavation design. However, these systems, developed primarily in the 1970s, lack access to modern…

Machine Learning · Computer Science 2024-11-26 T. F. Hansen , A. Aarset

One of the difficulties in 3D reconstruction of molecules from images in single particle Cryo-Electron Microscopy (Cryo-EM), in addition to high levels of noise and unknown image orientations, is heterogeneity in samples: in many cases, the…

Computer Vision and Pattern Recognition · Computer Science 2016-07-13 Roy R. Lederman , Amit Singer