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Objective: To study the longitudinal associations between inattention/hyperactivity symptoms and night-waking in preschool-years, in light of their joint evolution.Study design: Within the French birth-cohort study EDEN, repeated measures…
The aim of this study was to investigate human erythrocytes as a carrier for targeted drug delivery of primaquine (PQ). The process of PQ loading in human erythrocytes, as well as the effect of PQ loading on the oxidative status of…
Zebrafish are a common model organism used to identify new disease therapeutics. High-throughput drug screens can be performed on larval zebrafish in multi-well plates by observing changes in behaviour following a treatment. Analysis of…
False-positive results and bias may be common features of the biomedical literature today, including risk factor-chronic disease research. A study was undertaken to assess the reliability of base studies used in a meta-analysis examining…
Objective: Early identification of ADHD is necessary to provide the opportunity for timely treatment. However, screening the symptoms of ADHD on a large scale is not easy. This study aimed to validate a video game (FishFinder) for the…
An experiment was conducted to evaluate the effect of feeding post-weaned piglets different levels of a commercial amoxicillin plus norfloxacin formula (Respirend) on the performance, clinical evidence of sickness, and the cost:benefit…
We propose a frequentist adaptive phase 2 trial design to evaluate the safety and efficacy of three treatment regimens (doses) compared to placebo for four types of helminth (worm) infections. This trial will be carried out in four…
Based on approximately 90,000 confirmed dengue cases reported in Recife - a major city in northeastern Brazil - between 2015 and 2024, we conducted a neighborhood-level spatial analysis. Socioeconomic and demographic indicators from the…
Epilepsy is a prevalent neurological disorder affecting 50 million individuals worldwide and 1.2 million Americans. There exist millions of pediatric patients with intractable epilepsy, a condition in which seizures fail to come under…
Mosquitoes are vectors of many human diseases. In particular, Aedes \ae gypti (Linnaeus) is the main vector for Chikungunya, Dengue, and Zika viruses in Latin America and it represents a global threat. Public health policies that aim at…
SPECT imaging is one of the common modalities used to examine kidney disease. The radiopharmaceuticals such as 99mTc-MAG3, 99mTc-DTPA, and 99mTc-DMSA are commonly employed for pediatric patients. It is generally accepted that children…
Background: In 2015, the Zika arbovirus (ZIKV) began circulating in the Americas, rapidly expanding its global geographic range in explosive outbreaks. Unusual among mosquito-borne diseases, ZIKV has been shown to also be sexually…
Impact of EEG biofeedback on event-related potentials (ERPs) in attention-deficit hyperactivity (ADHD) children. Introduction: ADHD is one of the most widely spread condition of school aged children affecting 5% of children of this age.The…
Virtual reality (VR) is increasingly used across psychology, from research and assessment to counseling, psychological treatment, and psychotherapy, with growing applications for children and adolescents. In these contexts, VR is often…
This paper introduces a new multi-strain epidemic model with reinfection and cross-immunity to provide insights into the resurgence of the COVID-19 epidemic in an area with reportedly high seroprevalence due to a largely unmitigated…
Multiple instances of Zika virus epidemic have been reported around the world in the last two decades, turning the related illness into an international concern. In this context the use of mathematical models for epidemics is of great…
Mpox (formerly monkeypox) is a zoonotic disease caused by an orthopoxvirus closely related to variola and remains a significant global public health concern. During outbreaks, social media platforms like X (formerly Twitter) can both inform…
Delirium occurs in about 80% cases in the Intensive Care Unit (ICU) and is associated with a longer hospital stay, increased mortality and other related issues. Delirium does not have any biomarker-based diagnosis and is commonly treated…
Background: While the relations between sleep, cognition and behavior have been extensively studied in adolescents and school-aged children, very little attention has been given to preschoolers. Objective: In this systematic review, our aim…
Measles is an infectious disease caused by the Morbilivirus Measles Virus which has accompanied the human race since the 4th millennium BC, it is a disease usually concerning the paediatric population and in the past, before the advent of…