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Focal cortical dysplasias (FCDs) are the most common cause of treatment resistant epilepsy affecting the pediatric population. Most individuals with FCD have seizure onset during the first five years of life and the majority will have…
In this paper we study some deterministic mathematical models that seek to explain the expansion of zika virus, as a viral epidemic, using published data for Brazil. SIR type models are proposed and validated using the epidemic data found,…
Borrelia burgdorferi sensu stricto is a bacterial spirochete prevalent in the Northeastern United States that causes Lyme disease. Lyme disease is the most common arthropod-borne disease in the United States; affecting mice, deer, humans…
Naloxone, an opioid antagonist, has been widely used to save lives from opioid overdose, a leading cause for death in the opioid epidemic. However, naloxone has short brain retention ability, which limits its therapeutic efficacy.…
The present study investigates the compatibility of mycoinsecticides based on isolates IBCB66 and Simbi BB15 of Beauveria bassiana and Esalq-1296 of Cordyceps javanica, which are registered for the management of Dalbulus maidis in Brazil,…
Prion diseases are invariably fatal neurodegenerative diseases that affect humans and animals. Unlike most other amyloid forming neurodegenerative diseases, these can be highly infectious. Prion diseases occur in a variety of species. They…
Leprosy (Hansen's disease) is an infectious, neglected tropical disease caused by the Mycobacterium Leprae (M. Leprae). Each year there are approximately 2,02,189 new cases are detected globally. In the year 2017 more than half million…
Creutzfeldt-Jakob disease (CJD) is a rapidly progressive and fatal neurodegenerative disease, that causes approximately 350 deaths in the United States every year. In specific, it is a prion disease that is caused by a misfolded prion…
Epilepsy is a prevalent neurological disease with millions of patients worldwide. Many patients have turned to alternative medicine due to the limited efficacy and side effects of conventional antiepileptic drugs. In this study, we…
Mycobacterium leprae is a bacteria that causes the disease Leprosy (Hansen's disease), which is a neglected tropical disease. More than 200000 cases are being reported per year world wide. This disease leads to a chronic stage known as…
Hepatic encephalopathy is a neurological complication that affects attention and memory. Experimental animal models have been used to study hepatic Encephalopathy, the most frequent being the portacaval shunt. In order to determine learning…
Small molecules play a critical role in the biomedical, environmental, and agrochemical domains, each with distinct physicochemical requirements and success criteria. Although biomedical research benefits from extensive datasets and…
The slime mould Physarum polycephalum has been used in developing unconventional computing devices for in which the slime mould played a role of a sensing, actuating, and computing device. These devices treated the slime mould rather as an…
Evidence from animal models and epidemiological studies has linked prenatal alcohol exposure (PAE) to a broad range of long-term cognitive and behavioral deficits. However, there is virtually no information in the scientific literature…
Health is a very important prerequisite in peoples well-being and happiness. Several studies were more focused on presenting the occurrence on specific disease like forecasting the number of dengue and malaria cases. This paper utilized the…
Cataract is one of the most prevalent protein aggregation disorders and still the biggest cause of vision loss worldwide. The human lens, in its core region, lacks turnover of any cells or cellular components; it has therefore evolved…
Basic understanding of biological membranes is of paramount importance as these membranes comprise the very building blocks of life itself. Cells depend in their function on a range of properties of the membrane, which are important for the…
In developing countries, healthcare challenges and expensive infertility treatments has resulted in resurgent interest in medicinal plants. This study was designed to determine if Curcubita pepo seed can enhance female fertility, by…
The main reasons for the ongoing COVID-19 (coronavirus disease 2019) pandemic are the unavailability of recommended efficacious drugs or vaccines along with the human to human transmission nature of SARS-CoV-2 virus. So, there is urgent…
The opioid epidemic began with prescription pain relievers. In 2010 Purdue Pharma reformulated OxyContin to make it more difficult to abuse. OxyContin misuse fell dramatically, and concurrently heroin deaths began to rise. Previous research…