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We study a nonlocal adhesion model for two interacting tumor cell phenotypes, combining diffusion, pairwise interactions, and random phenotypic switching. The system admits a microscopic diffusion--jump particle description whose mean-field…

Analysis of PDEs · Mathematics 2026-03-16 Myeongju Chae , Young-Pil Choi

A novel numerical technique has been proposed to solve a two-phase tumour growth model in one spatial dimension without needing to account for the boundary dynamics explicitly. The equivalence to the standard definition of a weak solution…

Numerical Analysis · Mathematics 2019-02-19 Gopikrishnan C. Remesan

This paper presents an existence result for the anisotropic Cahn--Hilliard equation characterized by a potentially concentration-dependent degenerate mobility taking into account an anisotropic energy. The model allows for the degeneracy of…

Analysis of PDEs · Mathematics 2025-02-20 Harald Garcke , Patrik Knopf , Andrea Signori

We find an explicit form of weak solutions to a Riemann problem for a degenerate semilinear parabolic equation with piecewise constant diffusion coefficient. It is demonstrated that the phase transition lines (free boundaries) correspond to…

Analysis of PDEs · Mathematics 2022-11-01 Evgeny Yu. Panov

We study a nonlocal Cahn-Hilliard model for a multicomponent mixture with cross-diffusion effects and degenerate mobility. The nonlocality is described by means of a symmetric singular kernel. We define a notion of weak solution adapted to…

Analysis of PDEs · Mathematics 2026-05-22 Elisa Davoli , Greta Marino , Jan-Frederik Pietschmann

Volume-filling cross-diffusion equations for the components of a tissue structure are formally derived from mass conservation laws and force balances for the interphase pressures and viscous drag forces in a multiphase approach. The…

Analysis of PDEs · Mathematics 2026-04-03 Ansgar Jüngel , Cordula Reisch , Sara Xhahysa

We consider 1D dissipative transport equations with nonlocal velocity field: \[ \theta_t+u\theta_x+\delta u_{x} \theta+\Lambda^{\gamma}\theta=0, \quad u=\mathcal{N}(\theta), \] where $\mathcal{N}$ is a nonlocal operator given by a Fourier…

Analysis of PDEs · Mathematics 2018-04-25 Hantaek Bae , Rafael Granero-Belinchón , Omar Lazar

We present a phase-space analysis of a mathematical model of tumor growth with an immune responses. We consider mathematical analysis of the model equations with multipoint initial condition regarding to dissipativity, boundedness of…

Dynamical Systems · Mathematics 2019-02-28 Veli Shakhmurov , Rishad Shahmurov

We prove existence of weak solutions for a diffuse interface model for the flow of two viscous incompressible Newtonian fluids with different densities in a bounded domain in two and three space dimensions. In contrast to previous works, we…

Analysis of PDEs · Mathematics 2019-11-21 Helmut Abels , Yutaka Terasawa

A chemotaxis system possibly containing rotational components of the cross-diffusive flux is studied under no-flux boundary conditions in a bounded domain $\Omega\subset R^n$, $n\ge 1$, with smooth boundary, where the evolution of the…

Analysis of PDEs · Mathematics 2015-06-19 Michael Winkler

A nutrient-limited model for avascular cancer growth including cell proliferation, motility and death is presented. The model qualitatively reproduces commonly observed morphologies for primary tumors, and the simulated patterns are…

Statistical Mechanics · Physics 2011-03-09 S. C. Ferreira Junior , M. L. Martins , M. J. Vilela

In this paper, we propose a new mathematical model nonlinear reaction-diffusion PDE's describing the dynamics of propagation of cancer. Here the mixed problem for the proposed PDE's is investigated and by applying obtained results…

Analysis of PDEs · Mathematics 2022-01-10 Kamal N. Soltanov

The mathematical modeling of tumor growth leads to singular stiff pressure law limits for porous medium equations with a source term. Such asymptotic problems give rise to free boundaries, which, in the absence of active motion, are…

Analysis of PDEs · Mathematics 2015-07-06 Inwon C. Kim , Benoit Perthame , Panagiotis E. Souganidis

We consider a phase-field system modelling solid tumour growth. This system consists of a Cahn-Hilliard equation coupled with a nutrient equation. The former is characterised by a degenerate mobility and a singular potential. Both equations…

Analysis of PDEs · Mathematics 2025-12-18 Cecilia Cavaterra , Matteo Fornoni , Maurizio Grasselli , Benoît Perthame

In this paper, we consider a mathematical model for the invasion of host tissue by tumour cells in a $d$-dimensional bounded domain, $d\leq 3$. This model consists of a system of differential equations describing the evolution of cancer…

Numerical Analysis · Mathematics 2020-07-21 Viviana Niño-Celis , Diego Armando Rueda-Gómez , Élder Jesús Villamizar Roa

Systems of the type $$\begin{cases} u_t = \nabla \cdot (D_1(u) \nabla u - S_1(u) \nabla v) + f_1(u, v),\\ v_t = \nabla \cdot (D_2(v) \nabla v + S_2(v) \nabla u) + f_2(u, v) \end{cases} \qquad (\star)$$ can be used to model pursuit-evasion…

Analysis of PDEs · Mathematics 2022-01-19 Mario Fuest

We consider weak solutions for a diffuse interface model of two non-Newtonian viscous, incompressible fluids of power-law type in the case of different densities in a bounded, sufficiently smooth domain. This leads to a coupled system of a…

Analysis of PDEs · Mathematics 2017-01-03 Helmut Abels , Dominic Breit

In this article, we present a multispecies reaction-advection-diffusion partial differential equation (PDE) coupled with linear elasticity for modeling tumor growth. The model aims to capture the phenomenological features of glioblastoma…

Medical Physics · Physics 2019-05-28 Shashank Subramanian , Amir Gholami , George Biros

We consider a haptotaxis cancer invasion model that includes two families of cancer cells. Both families, migrate on the extracellular matrix and proliferate. Moreover the model describes an epithelial-to-mesenchymal-like transition between…

Analysis of PDEs · Mathematics 2023-03-01 Jan Giesselmann , Niklas Kolbe , Maria Lukacova-Medvidova , Nikolaos Sfakianakis

We consider a class of cross diffusion systems with degenerate (or porous media type) diffusion which is inspired by models in mathematical biology/ecology with zero self diffusions. Known techniques for scalar equations are no longer…

Analysis of PDEs · Mathematics 2019-09-12 Dung Le
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