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We study a PDE model for dynamics of susceptible-infected interactions. The dispersal of susceptibles is via diffusion and repellent taxis as they move away from the increasing density of infected. The diffusion of infected is a nonlinear,…
This work considers the propagation of high-frequency waves in highly-scattering media where physical absorption of a nonlinear nature occurs. Using the classical tools of the Wigner transform and multiscale analysis, we derive semilinear…
In this paper we consider a porous-elastic system consisting of nonlinear boundary/interior damping and nonlinear boundary/interior sources. Our interest lies in the theoretical understanding of the existence, finite time blow-up of…
In this paper, we study a cancer invasion model both theoretically and numerically. The model is a nonstationary, nonlinear system of three coupled partial differential equations modeling the motion of cancer cells, degradation of the…
This paper deals with the long-time behavior of solutions of nonlinear reaction-diffusion equations describing formation of morphogen gradients, the concentration fields of molecules acting as spatial regulators of cell differentiation in…
This paper is concerned with a multi-dimensional free boundary problem modeling the growth of a tumor with two species of cells: proliferating cells and quiescent cells. This free boundary problem has a unique radial stationary solution. By…
We study a system of reaction-diffusion equations posed on a bounded domain composed of subdomains separated by a connected network with a metric graph structure. The reaction-diffusion dynamics with anisotropic diffusion on the graph edges…
We analyze a diffuse interface model that couples a viscous Cahn-Hilliard equation for the phase variable with a diffusion-reaction equation for the nutrient concentration. The system under consideration also takes into account some…
We study a diffuse interface model describing the evolution of the flow of a binary fluid in a Hele-Shaw cell. The model consists of a Cahn-Hilliard-Darcy (CHD) type system with transport and mass source. A relevant physical application is…
In this paper, we develop a sharp interface tumor growth model to study the effect of the tumor microenvironment using a complex far-field geometry that mimics a heterogeneous distribution of vasculature. Together with different nutrient…
In this paper, we study an optimal control problem for a coupled non-linear system of reaction-diffusion equations with degenerate diffusion, consisting of two partial differential equations representing the density of cells and the…
Recent progress in microdissection and in DNA sequencing has enabled subsampling of multi-focal cancers in organs such as the liver in several hundred spots, helping to determine the pattern of mutations in each of these spots. This has led…
We study a model for a fluid showing viscoelastic and viscoplastic behavior, which describes the flow in terms of the fluid velocity and an internal stress. This stress tensor is transported via the Zaremba--Jaumann rate, and it is subject…
We study a class of lubrication-type equations modeling the spread of thin poroelastic biofilms at air/agar interfaces. Starting from a biofilm slab model, we perform a formal multi-scale asymptotic expansion to derive a reduced nonlinear…
We consider quasi-stationary (travelling wave type) solutions to a nonlinear reaction-diffusion equation with arbitrary, autonomous coefficients, describing the evolution of glioblastomas, aggressive primary brain tumors that are…
A mathematical model for the continuous nonlinear fragmentation equation is considered in the presence of mass transfer. In this paper, we demonstrate the existence of mass-conserving weak solutions to the nonlinear fragmentation equation…
Using analysis for 2-admissible functions in weighted Sobolev spaces and stochastic calculus for possibly degenerate symmetric elliptic forms, we construct weak solutions to a wide class of stochastic differential equations starting from an…
We prove existence of weak solutions for a diffuse interface model for the flow of two viscous incompressible Newtonian fluids in a bounded domain in two and three space dimensions. In contrast to previous works, we study a new model…
We analyze a diffuse interface model that describes the dynamics of incompressible two-phase flows with chemotaxis effect. The PDE system couples a Navier-Stokes equation for the fluid velocity, a convective Cahn-Hilliard equation for the…
Using basic thermodynamic principles we derive a Cahn--Hilliard--Darcy model for tumour growth including nutrient diffusion, chemotaxis, active transport, adhesion, apoptosis and proliferation. The model generalises earlier models and in…