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Imaging specimens over large scales and with a sub-micron resolution is instrumental to biomedical research. Yet, the number of pixels to form such an image usually exceeds the number of pixels provided by conventional cameras. While most…
Fundus photography is indispensable for clinical detection and management of eye diseases. Limited image contrast and field of view (FOV) are common limitations of conventional fundus cameras, making it difficult to detect subtle…
Fluorescence microscopy is widely used in biological imaging, however scattering from tissues strongly limits its applicability to a shallow depth. In this work we adapt a methodology inspired from stellar speckle interferometry, and…
This paper discusses the broad science case for obtaining milliarcsecond to microarcsecond astronomical imaging resolution in the soft to medium-energy X-ray band (~0.5 to ~8 keV). Astronomy across much of the electromagnetic spectrum has…
Gastrointestinal endoscopy is a medical procedure that utilizes a flexible tube equipped with a camera and other instruments to examine the digestive tract. This minimally invasive technique allows for diagnosing and managing various…
We present a dual color laser scanning endomicroscope capable of fluorescence lifetime endomicroscopy at one frame per second (FPS). The scanning system uses a coherent imaging fiber with 30,000 cores. High-speed lifetime imaging is…
Luminescence imaging is invaluable for studying biological and material systems, particularly when advanced protocols that exploit temporal dynamics are employed. However, implementing such protocols often requires custom instrumentation,…
Ultrathin lensless fibre endoscopes offer minimally invasive investigation, but they mostly operate as a rigid type due to the need for prior calibration of a fibre probe. Furthermore, most implementations work in fluorescence mode rather…
Recent advances in capsule endoscopy systems have introduced new methods and capabilities. The capsule endoscopy system, by observing the entire digestive tract, has significantly improved diagnosing gastrointestinal disorders and diseases.…
In vivo real-time epifluorescence imaging of mouse hindlimb vasculatures in the second near-infrared region (NIR-II, 1.1~1.4 microns) is performed using single-walled carbon nanotubes (SWNTs) as fluorophores. Both high spatial resolution…
Microscopy imaging systems with a very wide field-of-view (FOV) are highly sought in biomedical applications. In this paper, we report a wide FOV microscopy imaging system that uses a low-cost scanner and a closed-circuit-television (CCTV)…
Endomicroscopy is indispensable for minimally invasive diagnostics in clinical practice. For optical keyhole monitoring of surgical interventions, high-resolution fiber endoscopic imaging is considered to be very promising, especially in…
In this work we have determined the focal length of a concave lens by photographing the virtual image of an object by a smartphone camera. We have similarly determined the focal length of a convex lens by forming a virtual image of an…
Hyperspectral reconstruction (HSR) from RGB images is a highly promising direction for accurate color reproduction and material color measurement. While most existing approaches rely on a single RGB image - thereby limiting reconstruction…
Optical detection of nanoscale objects without relying on fluorescence is a current challenge due to their extremely weak interaction with light. Resonator-enhanced absorption microscopy is a novel tool to heavily boost the light-matter…
Super-resolution optical microscopy is a rapidly evolving scientific field dedicated to imaging sub-wavelength sized objects, leaving its mark in multiple branches of biology and technology. While several super-resolution optical microscopy…
The new trend of full-screen devices implies positioning the camera behind the screen to bring a larger display-to-body ratio, enhance eye contact, and provide a notch-free viewing experience on smartphones, TV or tablets. On the other…
The use of individual multimode optical fibers in endoscopy applications has the potential to provide highly miniaturized and noninvasive probes for microscopy and optical micromanipulation. A few different strategies have been proposed…
Fluorescence microscopy is a critical tool across various disciplines, from materials science to biomedical research, yet it is limited by the diffraction limit of resolution. Advanced super-resolution techniques such as localization…
Microscopy image enhancement plays a pivotal role in understanding the details of biological cells and materials at microscopic scales. In recent years, there has been a significant rise in the advancement of microscopy image enhancement,…