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Fluorescence imaging is the most widely used method for unveiling the molecular composition of biological specimens. However, the weak optical emission of fluorescent probes and the tradeoff between imaging speed and sensitivity is…

Lensless imaging enables exceptionally compact fluorescence sensors, advancing applications in \textit{in vivo} imaging and low-cost, point-of-care diagnostics. These sensors require a filter to block the excitation light while passing…

Image and Video Processing · Electrical Eng. & Systems 2026-02-20 Lukas Harris , Micah Roschelle , Jack Bartley , Mekhail Anwar

Accurate characterisation of margins in excised breast cancer tumours is critical to the success of surgical interventions, yet margin status is typically confirmed post-operatively using histopathology. Here we present a new approach to…

In recent years, light-sheet fluorescence microscopy (LSFM) has emerged as a powerful tool for visualizing and analyzing cancer tissue samples, including patient-derived specimens, organoids, biopsies, and murine models. In this work, we…

We suggest a low cost, non invasive healthcare system that measures haemoglobin levels in patients and can be used as a preliminary diagnostic test for anaemia. A combination of image processing, machine learning and deep learning…

Machine Learning · Computer Science 2020-12-01 Sarah , S. Sidhartha Narayan , Irfaan Arif , Hrithwik Shalu , Juned Kadiwala

Significance: Endoscopic screening for esophageal cancer may enable early cancer diagnosis and treatment. While optical microendoscopic technology has shown promise in improving specificity, the limited field of view (<1 mm) significantly…

Image and Video Processing · Electrical Eng. & Systems 2023-10-04 Xiaohui Zhang , Mimi Tan , Mansour Nabil , Richa Shukla , Shaleen Vasavada , Sharmila Anandasabapathy , Mark A. Anastasio , Elena Petrova

Smartphones have enabled effortless capturing and sharing of documents in digital form. The documents, however, often undergo various types of degradation due to aging, stains, or shortcoming of capturing environment such as shadow,…

Computer Vision and Pattern Recognition · Computer Science 2021-09-08 Soumyadeep Dey , Pratik Jawanpuria

Recent advances in camera design and imaging technology have enabled the capture of high-quality images using smartphones. However, due to the limited dynamic range of digital cameras, the quality of photographs captured in environments…

Image and Video Processing · Electrical Eng. & Systems 2024-10-02 Lucas Nedel Kirsten , Zhicheng Fu , Nikhil Ambha Madhusudhana

The primary focus of this research is the discreet and subtle everyday contact interactions between mobile phones and their surrounding surfaces. Such interactions are anticipated to facilitate mobile context awareness, encompassing aspects…

Human-Computer Interaction · Computer Science 2024-07-23 Yongquan Hu , Hui-Shyong Yeo , Mingyue Yuan , Haoran Fan , Don Samitha Elvitigala , Wen Hu , Aaron Quigley

Progress in performing angle-resolved photoemission spectroscopy (ARPES) with high spatial resolution in the order of 1~$\mu$m or less (nanoARPES) has opened the possibility to map the spectral function of solids on this tiny scale and…

Strongly Correlated Electrons · Physics 2021-05-24 Philip Hofmann

Medical imaging is an invaluable resource in medicine as it enables to peer inside the human body and provides scientists and physicians with a wealth of information indispensable for understanding, modelling, diagnosis, and treatment of…

Image and Video Processing · Electrical Eng. & Systems 2022-08-25 Hanene Ben Yedder , Ben Cardoen , Ghassan Hamarneh

Our work aims at using quantitative imaging tools to complement the limitation of noise encountered by high resolution fluorescence microscopy methods. Several cycles of fluorophore activation, imaging and deactivation produce a sequence of…

Quantitative Methods · Quantitative Biology 2012-02-03 Juliane Liepe , Federico Felizzi , Agata Pernus , Maria Hanulova

The vast majority of photos taken today are by mobile phones. While their quality is rapidly growing, due to physical limitations and cost constraints, mobile phone cameras struggle to compare in quality with DSLR cameras. This motivates us…

Computer Vision and Pattern Recognition · Computer Science 2019-01-01 Etienne de Stoutz , Andrey Ignatov , Nikolay Kobyshev , Radu Timofte , Luc Van Gool

Around-device interaction techniques aim at extending the input space using various sensing modalities on mobile and wearable devices. In this paper, we present our work towards extending the input area of mobile devices using front-facing…

Human-Computer Interaction · Computer Science 2017-09-05 Daniel Schneider , Jens Grubert

Microscopic analysis of micro particles in situ in diverse water environments is necessary for monitoring water quality and localizing contamination sources. Conventional sensors such as optical microscopes and fluorometers often require…

Robotics · Computer Science 2019-11-26 Kevin Mallery , Dario Canelon , Jiarong Hong , Nikolaos Papanikolopoulos

This work presents an inexpensive optical projection tomography (OPT) system built on a mobile phone platform for three-dimensional optical microscopy. The system uses an iPhone camera together with a low-cost commercial microscope lens…

Image and Video Processing · Electrical Eng. & Systems 2026-04-17 Gennifer T. Smith , James M. Sikes , Nicholas Dwork

The introduction of neuroendoscopy, microneurosurgery, neuronavigation, and intraoperative imaging for surgical operations has made significant improvements over other traditionally invasive surgical techniques. The integration of magnetic…

Systems and Control · Electrical Eng. & Systems 2022-09-20 Martin Francis Phelan , Nihal Olcay Dogan , Jelena Lazovic , Metin Sitti

Hyperspectral imaging acquires data in both the spatial and frequency domains to offer abundant physical or biological information. However, conventional hyperspectral imaging has intrinsic limitations of bulky instruments, slow data…

Image and Video Processing · Electrical Eng. & Systems 2023-04-06 Yuhyun Ji , Sang Mok Park , Semin Kwon , Jung Woo Leem , Vidhya Vijayakrishnan Nair , Yunjie Tong , Young L. Kim

Fluorescence microscopy has revolutionized biomedical research over the past three decades. Its high molecular specificity and unrivaled single molecule level sensitivity have enabled breakthroughs in a variety of research fields. For in…

Optics · Physics 2012-03-21 Meng Cui , Ke Si , Reto Fiolka

Far-field optical microscopy using focused light is an important tool in a number of scientific disciplines including chemical, (bio)physical and biomedical research, particularly with respect to the study of living cells and organisms.…