Related papers: Two-photon imaging through a multimode fiber
Multi-photon microscopy has played a significant role in biological imaging since it allows to observe living tissues with improved penetration depth and excellent sectioning effect. Multi-photon microscopy relies on multi-photon…
We introduce a imaging modality that works by transiently masking image-subregions during a single exposure of a CCD frame. By offsetting subregion exposure time, temporal information is embedded within each stored frame, allowing…
We demonstrate and study the enhancement of intermediate-field two-photon absorption by shaped femtosecond pulses having spectral phases of antisymmetric nature. The intermediate-field regime corresponds to pulse intensities, where the…
We report a systematic methodology to obtain supermodes with equidistant effective index distribution and to excite arbitrary target supermodes with high precision. By employing a multi-well optical potential realized by a judiciously…
Fiber-based endoscopes utilizing multi-core fiber (MCF) bundles offer the capability to image deep within the human body, making them well-suited for imaging applications in minimally invasive surgery or diagnosis. However, the optical…
We present a superpixel method for full spatial phase and amplitude control of a light beam using a digital micromirror device (DMD) combined with a spatial filter. We combine square regions of nearby micromirrors into superpixels by low…
Confocal and multiphoton microscopy are effective techniques to obtain high-contrast images of 2-D sections within bulk tissue. However, scattering limits their application to depths only up to ~1 millimeter. Multimode fibers make excellent…
We describe the apparatus of a fluorescence optical microscope with both single-photon and two-photon non-diffracting light sheets excitation for large volume imaging. With special design to accommodate two different wavelength ranges…
Two-Photon Microscopy (TPM) can provide three-dimensional morphological and functional contrast in vivo. Through proper staining, TPM can be utilized to create virtual, H&E equivalent images and thus can improve throughput in…
We present a table-top beamline providing a soft X-ray supercontinuum extending up to 350 eV from high-order harmonic generation with sub-13 fs 1300 nm driving pulses and simultaneous production of sub-5 fs pulses centered at 800 nm.…
We numerically analyze the use of intense entangled twin beams for ultra-sensitive spectroscopic measurements in chemical and biological systems. The examined scheme makes use of intense frequency-modulated (chirped) entangled beams to…
High spatio-angular resolution diffusion MRI (dMRI) has been shown to provide accurate identification of complex neuronal fiber configurations, albeit, at the cost of long acquisition times. We propose a method to recover intra-voxel fiber…
Multimode fibers (MMFs) show great promise as miniature probes for sensing, imaging and spectroscopy applications. Different parameters of the fibers, such as numerical aperture, refractive index profile and length, have been already…
Super-resolution fluorescence microscopy is an important tool in biomedical research for its ability to discern features smaller than the diffraction limit. However, due to its difficult implementation and high cost, the universal…
A general-purpose all-fiber spectrometer is demonstrated to overcome the trade-off between spectral resolution and bandwidth. By integrating a wavelength division multiplexer with five multimode optical fibers, we have achieved 100 nm…
When a two-level system -- a qubit -- is used as a probe of a larger system, it naturally leads to answering a single yes-no question about the system state. Here we propose a method where a single qubit is able to extract, not a single,…
Single fiber imaging technology offers unique insights for research and inspection in difficult to reach and narrow spaces. In particular, ultra-compact multimode fiber (MMF) imaging, has received increasing interest over the past decade.…
We report the application of fifth order nonlinear optical processes for multiphoton microscopy, including fifth harmonic and 5-photon excitation fluorescence. This novel imaging modality has been characterized with spectral and power…
We present the design, manufacturing technique, and characterization of a 3D-printed broadband graded index millimeter wave absorber. The absorber is additively manufactured using a fused filament fabrication (FFF) 3D printer out of a…
We introduce a wide field hyperspectral microscope using the Fourier-transform approach. The interferometer is based on the Translating-Wedge-Based Identical Pulses eNcoding System (TWINS) [Opt. Lett. 37, 3027 (2012)], a common-path…