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This paper presents a novel swarm robotics application of chemotaxis behaviour observed in microorganisms. This approach was used to cause exploration robots to return to a work area around the swarm's nest within a boundless environment.…

Robotics · Computer Science 2019-06-19 Simon O. Obute , Mehmet R. Dogar , Jordan H. Boyle

Living cells often need to measure chemical concentrations that vary in time. To this end, they deploy many resources, e.g. receptors, downstream signaling molecules, time and energy. Here, we present a theory for the optimal design of a…

Molecular Networks · Quantitative Biology 2019-02-26 G. Malaguti , P. R. ten Wolde

Models for chemotaxis are based on gradient sensing of individual organisms. The key contribution of Keller and Segel is showing that erratic movements of individuals may result in an accurate chemotaxis phenomenon as a group. In this paper…

Populations and Evolution · Quantitative Biology 2013-07-31 Changwook Yoon , Yong-Jung Kim

Cells perform directed motion in response to external stimuli that they detect by sensing the environment with their membrane protrusions. In particular, several biochemical and biophysical cues give rise to tactic migration in the…

Cell Behavior · Quantitative Biology 2020-07-15 N. Loy , M. Conte

We consider a minimal model of persistent random searcher with short range memory. We calculate exactly for such searcher the mean first-passage time to a target in a bounded domain and find that it admits a non trivial minimum as function…

Statistical Mechanics · Physics 2012-02-28 V. Tejedor , R. Voituriez , O. Bénichou

Chemotaxis, i.e. motion generated by chemical gradients, is a motility mode shared by many living species that has been developed by evolution to optimize certain biological processes such as foraging or immune response. In particular,…

Soft Condensed Matter · Physics 2023-05-24 Hugues Meyer , Heiko Rieger

Biological cells are able to accurately sense chemicals with receptors at their surfaces, allowing cells to move towards sources of attractant and away from sources of repellent. The accuracy of sensing chemical concentration is ultimately…

Subcellular Processes · Quantitative Biology 2015-05-14 Robert G. Endres , Ned S. Wingreen

During the past century, biologists and mathematicians investigated two mechanisms underlying bacteria motion: the run phase during which bacteria move in straight lines and the tumble phase in which they change their orientation. When…

Analysis of PDEs · Mathematics 2025-05-19 Alain Blaustein

We study the hunting process for a target, in which the hunter tracks the goal by smelling odors it emits. The odor intensity is supposed to decrease with the distance it diffuses. The Monte Carlo experiment is carried out on a…

Statistical Mechanics · Physics 2009-11-10 Shi-Jie Yang

Migrating cells exhibit various motility patterns, resulting from different migration mechanisms, cell properties, or cell-environment interactions. The complexity of cell dynamics is reflected, e.g., in the diversity of the observed forms…

Biological Physics · Physics 2023-07-07 M. Reza Shaebani , Matthieu Piel , Franziska Lautenschläger

Bird migration is an adaptive behavior ultimately aiming at optimizing survival and reproductive success. We propose an optimal switching model to study bird migration, where birds' migration behaviors can be efficiently modeled as…

Optimization and Control · Mathematics 2025-01-14 Jiawei Chu , King-Yeung Lam , Boyu Wang , Tong Wang

Inspired by bacterial chemotaxis we propose a hydrodynamic molecular scale hunter that can swim and find its target. The system is essentially a stochastic low Reynolds swimmer with ability to move in two dimensional space and sense the…

Soft Condensed Matter · Physics 2015-05-20 Ali Najafi

{\sl Escherichia coli} ({\sl E. coli}) bacteria govern their trajectories by switching between running and tumbling modes as a function of the nutrient concentration they experienced in the past. At short time one observes a drift of the…

Statistical Mechanics · Physics 2011-12-08 Sakuntala Chatterjee , Rava Azeredo da Silveira , Yariv Kafri

In this paper, we investigate a pursuit-evasion game in which a mobile observer tries to track a target in an environment containing obstacles. We formulate the game as an optimal control problem with state inequality constraint in a simple…

Optimization and Control · Mathematics 2016-11-16 Rui Zou , Hamid Emadi , Sourabh Bhattacharya

Aberrantly regulated cell motility is a hallmark of cancer cells. A hybrid agent-based model has been developed to investigate the synergistic and antagonistic cell motility-impacting effects of three microenvironment variables…

Cell Behavior · Quantitative Biology 2008-06-26 L. Leon Chen , Le Zhang , Jeongah Yoon , Thomas S. Deisboeck

Animal locomotion is often subject to constraints arising from anatomical/physiological asymmetries. We use the nematode C.~elegans as a minimal model system to ask whether such constraints might shape locomotion patterns optimized during…

Neurons and Cognition · Quantitative Biology 2024-01-17 W. Mathijs Rozemuller , Steffen Werner , Antonio Carlos Costa , Liam O'Shaughnessy , Greg J. Stephens , Thomas S. Shimizu

We theoretically address minimal search strategies of active, self-propelled particles towards hidden targets in three-dimensional space. The particles can sense if a target is close, e.g., by detecting signaling molecules released by a…

Soft Condensed Matter · Physics 2021-03-22 Justus A. Kromer , Andrea Auconi , Benjamin M. Friedrich

We introduce a model of interacting random walkers on a finite one dimensional chain with absorbing boundaries or targets at the ends. Walkers are of two types: informed particles that move ballistically towards a given target, and…

Statistical Mechanics · Physics 2015-02-20 Ricardo Martinez-Garcia , Cristobal Lopez , Federico Vazquez

Foraging, either solitarily or collectively, is a necessary behavior for survival that is demonstrated by many organisms. Foraging can be collectively optimized by utilizing communication between the organisms. Examples of such…

Biological Physics · Physics 2018-10-17 Noriyuki P. Tani , Alan Blatt , David A. Quint , Ajay Gopinathan

Background: Living cells of many types need to move in response to external stimuli in order to accomplish their functional tasks; these tasks range from wound healing to immune response to fertilization. While the directional motion is…

Cell Behavior · Quantitative Biology 2015-05-28 Inbal Hecht , Herbert Levine , Wouter-Jan Rappel , Eshel Ben-Jacob
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