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Intracellular components explore the cytoplasm via active motor-driven transport in conjunction with passive diffusion. We model the motion of organelles in narrow tubular cells using analytical techniques and numerical simulations to study…

Biological Physics · Physics 2018-04-11 Saurabh Mogre , Elena F. Koslover

To achieve optimal robot behavior in dynamic scenarios we need to consider complex dynamics in a predictive manner. In the vehicle dynamics community, it is well know that to achieve time-optimal driving on low surface, the vehicle should…

Robotics · Computer Science 2023-03-28 Zlatan Ajanović , Enrico Regolin , Barys Shyrokau , Hana Ćatić , Martin Horn , Antonella Ferrara

Bacteria track chemical gradients using a biased random walk, a process called chemotaxis. Experiments suggest that bacteria also communicate during this process. Using a mathematical model, we find that sufficiently strong communication…

Biological Physics · Physics 2025-12-18 Soutick Saha , Sean Fancher , Andrew Mugler

We propose a bio-inspired, agent-based approach to describe the natural phenomenon of group chasing in both two and three dimensions. Using a set of local interaction rules we created a continuous-space and discrete-time model with time…

Biological Physics · Physics 2017-05-24 Milán Janosov , Csaba Virágh , Gábor Vásárhelyi , Tamás Vicsek

In this study, we analyse a high-frequency movement dataset for a group of grazing cattle and investigate their spatiotemporal patterns using a simple two-state `stop-and-move' mobility model. We find that the dispersal kernel in the moving…

Quantitative Methods · Quantitative Biology 2016-03-18 Kun Zhao , Raja Jurdak

In this paper, a distributed convex optimization problem with swarm tracking behavior is studied for continuous-time multi-agent systems. The agents' task is to drive their center to track an optimal trajectory which minimizes the sum of…

Optimization and Control · Mathematics 2015-07-20 Salar Rahili , Wei Ren , Sheida Ghapani

Motivated by the observation of non-exponential run-time distributions of bacterial swimmers, we propose a minimal phenomenological model for taxis of active particles whose motion is controlled by an internal clock. The ticking of the…

Biological Physics · Physics 2020-07-23 Luis Gómez Nava , Robert Großmann , Marius Hintsche , Carsten Beta , Fernando Peruani

The response of microbes to external signals is mediated by biochemical networks with intrinsic time scales. These time scales give rise to a memory that impacts cellular behaviour. Here we study theoretically the role of cellular memory in…

Biological Physics · Physics 2020-02-14 Adam Gosztolai , Mauricio Barahona

Cells use temporal dynamical patterns to transmit information via signaling pathways. As optimality with respect to the environment plays a fundamental role in biological systems, organisms have evolved optimal ways to transmit information.…

Biological Physics · Physics 2016-12-21 Yoshihiko Hasegawa

Diffusion of tracer particles in the cytoplasm of mammalian cells is often anomalous with a marked heterogeneity even within individual particle trajectories. Despite considerable efforts, the mechanisms behind these observations have…

Biological Physics · Physics 2020-08-05 Adal Sabri , Xinran Xu , Diego Krapf , Matthias Weiss

Nature is in constant flux, so animals must account for changes in their environment when making decisions. How animals learn the timescale of such changes and adapt their decision strategies accordingly is not well understood. Recent…

Neurons and Cognition · Quantitative Biology 2018-12-24 Zachary P. Kilpatrick , William R. Holmes , Tahra L. Eissa , Krešimir Josić

Chemotaxis of bacterial swimmers that move in a run-and-turn pattern is well studied in uniform bulk fluid. It is primarily based on modulating the run time in dependence on the swimming direction with respect to the source of…

Soft Condensed Matter · Physics 2025-03-10 Sönke Beier , Veronika Pfeifer , Agniva Datta , Robert Großmann , Carsten Beta

We study a model of cell motility where the condition of optimal trade-off between performance and metabolic cost can be made precise. In this model a steadily crawling fragment is represented by a layer of active gel placed on a frictional…

Biological Physics · Physics 2015-06-18 P. Recho , J. -F. Joanny , L. Truskinovsky

Cells are constantly exposed to diverse stimuli-chemical, mechanical, or electrical-that guide their movement. In physiological conditions, these signals often overlap, as seen during infections, where neutrophils and dendritic cells…

Biological Physics · Physics 2026-03-25 Emiliano Perez Ipiña , Brian A. Camley

Natural systems often exhibit chaotic behavior in their space-time evolution. Systems transiting between chaos and order manifest a potential to compute, as shown with cellular automata and artificial neural networks. We demonstrate that…

Computational Physics · Physics 2025-04-08 Tomáš Vantuch , Ivan Zelinka , Andrew Adamatzky , Norbert Marwan

Noise in transduction of chemotactic stimuli to the flagellar motor of E. coli will affect the random run-and-tumble motion of the cell and the ability to perform chemotaxis. Here we use numerical simulations to show that an intermediate…

Cell Behavior · Quantitative Biology 2012-10-05 Marlo Flores , Thomas S. Shimuzu , Pieter Rein ten Wolde , Filipe Tostevin

This brief proposes a quasi time-fuel optimal control strategy to solve the dynamic tracking problem of unmanned systems when fuel and control input are limited. This kind of motion planning and control strategy could bring the biggest…

Popular Physics · Physics 2021-11-25 Huaihang Zheng , Junzheng Wang , Dawei Shi , Dongchen Liu , Shoukun Wang

Extending the classic works of Berg and Purcell on the biophysics of bacterial chemotaxis, we find the optimal chemotactic strategy for the peritrichous bacterium E. Coli in the high and low signal to noise ratio limits. The optimal…

adap-org · Physics 2009-10-30 S. P. Strong , B. Freedman , William Bialek , R. Koberle

The behavior of the maximal displacement of a supercritical branching random walk has been a subject of intense studies for a long time. But only recently the case of time-inhomogeneous branching has gained focus. The contribution of this…

Probability · Mathematics 2021-12-23 Bastien Mallein , Piotr Miłoś

Efficient navigation in swarms often relies on the emergence of decentralized approaches that minimize traversal time or energy. Stigmergy, where agents modify a shared environment that then modifies their behavior, is a classic mechanism…

Neurons and Cognition · Quantitative Biology 2026-01-08 Vishaal Krishnan , L. Mahadevan
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