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Biological systems like ciliated microorganisms are capable to respond to the external chemical gradients, a process known as chemotaxis which has been studied here using the chiral squirmer model. This theoretical model considers the…

Biological Physics · Physics 2018-04-18 Ruma Maity , P. S. Burada

The pursuit-evasion game is studied for two adversarial active agents, modelled as a deterministic self-steering pursuer and a stochastic, cognitive evader. The pursuer chases the evader by reorienting its propulsion direction with limited…

Biological Physics · Physics 2026-05-29 Segun Goh , Dennis Haustein , Gerhard Gompper

Animals foraging alone are hypothesized to optimize the encounter rates with resources through L\'evy walks. However, the issue of how the interactions between multiple foragers influence their search efficiency is still not completely…

Biological Physics · Physics 2013-11-12 Kunal Bhattacharya , Tamás Vicsek

We seek to characterize the motility of mouse fibroblasts on 2D substrates. Utilizing automated tracking techniques, we find that cell trajectories are super-diffusive, where displacements scale faster than t^(1/2) in all directions. Two…

Soft Condensed Matter · Physics 2017-12-15 G Passucci , ME Brasch , JH Henderson , V Zaburdaev , ML Manning

Most of our understanding of bacterial chemotaxis comes from studies of Escherichia coli. However, recent evidence suggests significant departures from the E. coli paradigm in other bacterial species. This variation may stem from different…

Cell Behavior · Quantitative Biology 2015-03-27 Martin Godány , Bhavin S. Khatri , Richard A. Goldstein

Chemotaxis and haptotaxis have been a main theme in the macroscopic study of bacterial and cellular motility. In this work we investigate the influence these processes have on the shape and motility of fast migrating cells. We note that…

Cell Behavior · Quantitative Biology 2016-12-08 Aaron Brunk , Niklas Kolbe , Nikolaos Sfakianakis

Single-cell organisms and various cell types use a range of motility modes when following a chemical gradient, but it is unclear which mode is best suited for different gradients. Here, we model directional decision-making in chemotactic…

Cell Behavior · Quantitative Biology 2025-05-12 Albert Alonso , Julius B. Kirkegaard , Robert G. Endres

Immune cells have evolved to recognize and eliminate pathogens, and the efficiency of this process can be measured in a Petri dish. Yet, even if the cells are time-lapse recorded and tracked with high resolution, it is difficult to judge…

Quantitative Methods · Quantitative Biology 2019-06-21 Claus Metzner

Escherichia coli is a motile bacterium that moves up a chemoattractant gradient by performing a biased random walk composed of alternating runs and tumbles. Previous models of run and tumble chemotaxis neglect one or more features of the…

Quantitative Methods · Quantitative Biology 2007-06-26 J. T. Locsei

Recent research highlighted the scaling property of human and animal mobility. An interesting issue is that the exponents of scaling law for animals and humans in different situations are quite different. This paper proposes a general…

Biological Physics · Physics 2011-11-01 Yanqing Hu , Jiang Zhang , Di Huan , Zengru Di

Eukaryotic cells are large enough to detect signals and then orient to them by differentiating the signal strength across the length and breadth of the cell. Amoebae, fibroblasts, neutrophils and growth cones all behave in this way. Little…

Cell Behavior · Quantitative Biology 2008-05-19 Liang Li , Simon F. Norrelykke , Edward C. Cox

The bacterium E.Coli swims in a zig-zag manner, in a series of straight runs and tumbles occurring alternately, with the run-durations dependent on the local spatial gradient of chemo-attractants/repellants. This enables the organism to…

Cell Behavior · Quantitative Biology 2008-12-31 Melissa Reneaux , Manoj Gopalakrishnan

Escherichia coli is a motile bacterium that moves up a chemoattractant gradient by performing a biased random walk composed of alternating runs and tumbles. This paper presents calculations of the chemotactic drift velocity vd (the mean…

Quantitative Methods · Quantitative Biology 2008-04-16 J. T. Locsei , T. J. Pedley

Agents searching for a target can improve their efficiency by memorizing where they have already been searching or by cooperating with other searchers and using strategies that benefit from collective effects. This chapter reviews such…

Statistical Mechanics · Physics 2023-11-10 Hugues Meyer , Heiko Rieger

Bacteria typically reside in heterogeneous environments with various chemogradients where motile cells can gain an advantage over non-motile cells. Since motility is energetically costly, cells must optimize their swimming speed and…

Populations and Evolution · Quantitative Biology 2020-05-05 Gurdip Uppal , Weiyi Hu , Dervis Can Vural

Cell migration in morphogenesis and cancer metastasis typically involves interplay between different cell types. We construct and study a minimal, one-dimensional model comprised of two different motile cells with each cell represented as…

Soft Condensed Matter · Physics 2017-09-20 David Mayett , Nicholas Bitten , Moumita Das , J. M. Schwarz

Pursuing a drifting target in a turbulent flow is an extremely difficult task whenever the searcher has limited propulsion and maneuvering capabilities. Even in the case when the relative distance between pursuer and target stays below the…

Fluid Dynamics · Physics 2023-10-02 Chiara Calascibetta , Luca Biferale , Francesco Borra , Antonio Celani , Massimo Cencini

Eukaryotic cells are able to sense chemical gradients in a wide range of environments. We show that, if a cell is exposed to a highly variable environment, it may gain chemotactic accuracy by expressing multiple receptor types with varying…

Cell Behavior · Quantitative Biology 2020-11-04 Austin Hopkins , Brian A. Camley

We study the chemotaxis of a population of genetically identical swimming bacteria undergoing run and tumble dynamics driven by stochastic switching between clockwise and counterclockwise rotation of the flagellar rotary system.…

Cell Behavior · Quantitative Biology 2020-07-17 Margaritis Voliotis , Jerko Rosko , Teuta Pilizota , Tanniemola Liverpool

A large variety of microorganisms produce molecules to communicate via complex signaling mechanisms such as quorum sensing and chemotaxis. The biological diversity is enormous, but synthetic inanimate colloidal microswimmers mimic…

Soft Condensed Matter · Physics 2019-10-01 Jens Grauer , Hartmut Löwen , Avraham Be'er , Benno Liebchen