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The basic and effective reproduction numbers are widely used metrics for characterizing the dynamics of infectious disease epidemics. However, the interpretation of these numbers is based on the assumption of homogeneous mixing and may not…

Populations and Evolution · Quantitative Biology 2026-03-24 Zahra Ghadiri , Jari Saramäki , Takayuki Hiraoka

When an infectious disease strikes a population, the number of newly reported cases is often the only available information that one can obtain during early stages of the outbreak. An important goal of early outbreak analysis is to obtain a…

Quantitative Methods · Quantitative Biology 2013-05-30 Bahman Davoudi , Babak Pourbohloul , Joel Miller , Rafael Meza , Lauren Ancel Meyers , David J. D. Earn

A social (sexual) network is modeled by an extension of the configuration model to the situation where edges have weights, e.g. reflecting the number of sex-contacts between the individuals. An epidemic model is defined on the network such…

Probability · Mathematics 2011-12-21 Tom Britton , David Lindenstrand

In this study, we investigate a stochastic SIR model with media effects. The uniqueness and the existence of a global positive solution are studied. The sufficient conditions of extinction and persistence of the disease are established. We…

Populations and Evolution · Quantitative Biology 2023-09-18 Jiaxun Li , Yanni Xiao

We investigate the long-time dynamics of a SIR epidemic model with infinitely many pathogen variants infecting a homogeneous host population. We show that the basic reproduction number $\mathcal{R}_0$ of the pathogen can be defined in that…

Populations and Evolution · Quantitative Biology 2023-05-11 Jean-Baptiste Burie , Arnaud Ducrot , Quentin Griette

Many infectious diseases can lead to re-infection. We examined the relationship between the prevalence of repeat infection and the basic reproductive number (R0). First we solved a generic, deterministic compartmental model of re-infection…

Populations and Evolution · Quantitative Biology 2019-03-15 Joshua Feldman , Sharmistha Mishra

We present a mathematical model for within host viral infections that incorporates the Crowley Martin functional response, focusing on the dynamics influenced by periodic effects. This study establishes key properties of the model,…

Dynamical Systems · Mathematics 2025-03-14 Ibrahim Nali , Attila Dénes

In the face of an infectious disease, a key epidemiological measure is the basic reproduction number, which quantifies the average secondary infections caused by a single case in a susceptible population. In practice, the effective…

Physics and Society · Physics 2025-03-11 Xin-Jian Xu , Song-Jie He , Li-Jie Zhang

Many real epidemics of an infectious disease are not straightforwardly super- or sub-critical, and the understanding of epidemic models that exhibit such complexity has been identified as a priority for theoretical work. We provide insights…

Probability · Mathematics 2018-02-23 Graham Brightwell , Thomas House , Malwina Luczak

A two-step contagion model with a single seed serves as a cornerstone for understanding the critical behaviors and underlying mechanism of discontinuous percolation transitions induced by cascade dynamics. When the contagion spreads from a…

Statistical Mechanics · Physics 2017-06-21 Wonjun Choi , Deokjae Lee , B. Kahng

This paper is concerned with a nonlocal dispersal susceptible-infected-susceptible (SIS) epidemic model with Dirichlet boundary condition, where the rates of disease transmission and recovery are assumed to be spatially heterogeneous. We…

Analysis of PDEs · Mathematics 2016-01-21 Fei-Ying Yang , Wan-Tong Li

The basic reproduction number ($R_0$) is an epidemiological metric that represents the average number of new infections caused by a single infectious individual in a completely susceptible population. The methodology for calculating this…

Algebraic Topology · Mathematics 2025-12-05 Trevor Reckell , Beckett Sterner , Petar Jevtić

This paper presents a disease-severity-structured epidemic model with treatment necessary only to severe infective individuals to discuss the effect of the treatment capacity on the disease transmission. It is shown that a backward…

Populations and Evolution · Quantitative Biology 2021-10-05 Hiromu Gion , Yasuhisa Saito

In the simple mean-field SIS and SIR epidemic models, infection is transmitted from infectious to susceptible members of a finite population by independent $p-$coin tosses. Spatial variants of these models are proposed, in which finite…

Probability · Mathematics 2009-09-29 Steven P. Lalley

We propose a stochastic model for evolution. Births and deaths of species occur with constant probabilities. Each new species is associated with a fitness sampled from the uniform distribution on [0,1]. Every time there is a death event…

Probability · Mathematics 2010-11-09 Herve Guiol , Fabio P. Machado , Rinaldo B. Schinazi

In this article, we introduce an infinite-dimensional deterministic SIS model which takes into account the heterogeneity of the infections and the social network among a large population. We study the long-time behavior of the dynamic. We…

Dynamical Systems · Mathematics 2020-06-16 Jean-François Delmas , Dylan Dronnier , Pierre-André Zitt

A general stochastic model for susceptible -> infective -> recovered (SIR) epidemics in non homogeneous populations is considered. The heterogeneity is a very important aspect here since it allows more realistic but also more complex…

Populations and Evolution · Quantitative Biology 2020-08-13 Zeynep Gökçe İşlier , Wolfgang Hörmann , Refik Güllü

The basic reproduction number $R_0$ is a fundamental quantity in epidemiological modeling, reflecting the typical number of secondary infections that arise from a single infected individual. While $R_0$ is widely known to scientists,…

Optimization and Control · Mathematics 2022-09-05 Kevin D. Smith , Francesco Bullo

Physiological stress fundamentally alters disease susceptibility in aquatic environments. In this paper, we develop a stress-structured epidemiological model where host vulnerability is dynamically driven by water quality. Analytically, we…

Populations and Evolution · Quantitative Biology 2026-02-10 Clotilde Djuikem , Julien Arino

We study that the breakdown of epidemic depends on some parameters, that is expressed in epidemic reproduction ratio number. It is noted that when $R_0 $ exceeds 1, the stochastic model have two different results. But, eventually the…

Statistics Theory · Mathematics 2018-03-19 Kurnia Susvitasari