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Boolean networks have been the object of much attention, especially since S. Kauffman proposed them in the 1960's as models for gene regulatory networks. These systems are characterized by being defined on a Boolean state space and by…

Molecular Networks · Quantitative Biology 2008-01-30 Winfried Just , German Enciso

Topology inference is a powerful tool to better understand the behaviours of network systems (NSs). Different from most of prior works, this paper is dedicated to inferring the directed topology of NSs from noisy observations, where the…

Systems and Control · Electrical Eng. & Systems 2025-09-03 Qing Jiao , Yushan Li , Jianping He

Complex systems are often modeled as Boolean networks in attempts to capture their logical structure and reveal its dynamical consequences. Approximating the dynamics of continuous variables by discrete values and Boolean logic gates may,…

Molecular Networks · Quantitative Biology 2013-05-29 Johannes Norrell , Joshua E. S. Socolar

The regulation of the cell state is a complex process involving several components. These complex dynamics can be modeled using Boolean networks, allowing us to explain the existence of different cell states and the transition between them.…

Molecular Networks · Quantitative Biology 2010-01-28 Elke K. Markert , Nils Baas , Arnold J. Levine , Alexei Vazquez

Boolean networks, first developed in the late 1960s as a tool for studying complex disordered dynamical systems, consist of nodes governed by Boolean functions whose evolution is entirely deterministic in that the state of the network at a…

Quantum Physics · Physics 2023-03-02 Ian T. Durham

A major goal in genomics is to properly capture the complex dynamical behaviors of gene regulatory networks (GRNs). This includes inferring the complex interactions between genes, which can be used for a wide range of genomics analyses,…

Molecular Networks · Quantitative Biology 2023-01-18 Mohammad Alali , Mahdi Imani

Control of a dynamical system without the knowledge of dynamics is an important and challenging task. Modern machine learning approaches, such as deep neural networks (DNNs), allow for the estimation of a dynamics model from control inputs…

Systems and Control · Electrical Eng. & Systems 2023-11-14 Suruchi Sharma , Volodymyr Makarenko , Gautam Kumar , Stas Tiomkin

Gene regulatory networks (GRNs) play a central role in cellular decision-making. Understanding their structure and how it impacts their dynamics constitutes thus a fundamental biological question. GRNs are frequently modeled as Boolean…

Molecular Networks · Quantitative Biology 2024-01-19 Claus Kadelka , Taras-Michael Butrie , Evan Hilton , Jack Kinseth , Addison Schmidt , Haris Serdarevic

A Boolean network (BN) is called observable if any initial state can be uniquely determined from the output sequence. In the existing literature on observability of BNs, there is almost no research on the relationship between the number of…

Systems and Control · Electrical Eng. & Systems 2024-07-29 Liangjie Sun , Wai-Ki Ching , Tatsuya Akutsu

We study information processing in populations of Boolean networks with evolving connectivity and systematically explore the interplay between the learning capability, robustness, the network topology, and the task complexity. We solve a…

Disordered Systems and Neural Networks · Physics 2015-03-19 Alireza Goudarzi , Christof Teuscher , Natali Gulbahce , Thimo Rohlf

In this paper, we discuss the relationships between capacity of control in entropy theory and intrinsic properties in control theory for a class of finite dimensional stochastic dynamical systems described by a linear stochastic…

Optimization and Control · Mathematics 2019-01-31 Salah H. Abid , Uday J. Quaez

In automata networks, it is well known that the way entities update their states over time has a major impact on their dynamics. In particular, depending on the chosen update schedule, the underlying dynamical systems may exhibit more or…

Discrete Mathematics · Computer Science 2022-04-25 Jacques Demongeot , Sylvain Sené

Boolean network (BN) is a simple model widely used to study complex dynamic behaviour of biological systems. Nonetheless, it might be difficult to gather enough data to precisely capture the behavior of a biological system into a set of…

Molecular Networks · Quantitative Biology 2020-09-02 Lubos Brim , Samuel Pastva , David Safranek , Eva Smijakova

It has been shown \citep{broeck90:physicalreview,patarnello87:europhys} that feedforward Boolean networks can learn to perform specific simple tasks and generalize well if only a subset of the learning examples is provided for learning.…

Neural and Evolutionary Computing · Computer Science 2019-11-12 Alireza Goudarzi , Christof Teuscher , Natali Gulbahce , Thimo Rohlf

Boolean functions and networks are commonly used in the modeling and analysis of complex biological systems, and this paradigm is highly relevant in other important areas in data science and decision making, such as in the medical field and…

Artificial Intelligence · Computer Science 2020-06-02 Jie Sun , Abd AlRahman AlMomani , Erik Bollt

Intracellular networks process cellular-level information and control cell fate. They can be computationally modeled using Boolean networks, which are implicit-time causal models of discrete binary events. These networks can be embedded in…

Molecular Networks · Quantitative Biology 2025-01-28 John Metzcar , Katie Pletz , Heber L. Rocha , Jordan C Rozum

The minimum number of inputs needed to control a network is frequently used to quantify its controllability. Control of linear dynamics through a minimum set of inputs, however, often has prohibitively large energy requirements and there is…

Computational Engineering, Finance, and Science · Computer Science 2022-12-12 Samie Alizadeh , Márton Pósfai , Abdorasoul Ghasemi

The theoretical explanation for deep neural network (DNN) is still an open problem. In this paper DNN is considered as a discrete-time dynamical system due to its layered structure. The complexity provided by the nonlinearity in the…

Machine Learning · Computer Science 2019-01-09 Husheng Li

A reflection of our ultimate understanding of a complex system is our ability to control its behavior. Typically, control has multiple prerequisites: It requires an accurate map of the network that governs the interactions between the…

Systems and Control · Computer Science 2016-09-21 Yang-Yu Liu , Albert-Laszló Barabási

We consider a network of identical, first-order linear systems, and investigate how replacing a subset of the systems composing the network with higher-order ones, either taken to be generic or specifically designed, may affect its…

Optimization and Control · Mathematics 2025-04-25 Marco Peruzzo , Giacomo Baggio , Francesco Ticozzi
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