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Biological networks such as gene regulatory networks possess desirable properties. They are more robust and controllable than random networks. This motivates the search for structural and dynamical features that evolution has incorporated…

Molecular Networks · Quantitative Biology 2024-02-16 Claus Kadelka , David Murrugarra

Due to the scarcity of quantitative details about biological phenomena, quantitative modeling in systems biology can be compromised, especially at the subcellular scale. One way to get around this is qualitative modeling because it requires…

Molecular Networks · Quantitative Biology 2019-03-22 Arnaud Poret , Claudio Monteiro Sousa , Jean-Pierre Boissel

Entanglement-based quantum networks exhibit a unique flexibility in the choice of entangled resource states that are then locally manipulated by the nodes to fulfill any request in the network. Furthermore, this manipulation is not uniquely…

Quantum Physics · Physics 2025-02-04 Maria Flors Mor-Ruiz , Julius Wallnöfer , Wolfgang Dür

Standard Random Boolean Networks display an order-disorder phase transition. We add to the standard Random Boolean Networks a disconnection rule which couples the control and order parameters. By this way, the system is driven to the…

Disordered Systems and Neural Networks · Physics 2009-11-07 Bartolo Luque , Fernando J. Ballesteros , Enrique M. Muro

The dynamics of Boolean networks (BN) with quenched disorder and thermal noise is studied via the generating functional method. A general formulation, suitable for BN with any distribution of Boolean functions, is developed. It provides…

Disordered Systems and Neural Networks · Physics 2015-05-27 Alexander Mozeika , David Saad

We study the stability of orbits in large Boolean networks with given complex topology. We impose no restrictions on the form of the update rules, which may be correlated with local topological properties of the network. While recent past…

Physics and Society · Physics 2014-09-05 Shane Squires , Andrew Pomerance , Michelle Girvan , Edward Ott

We consider the problem of making a set of states invariant for a network of controlled systems. We assume that the subsystems, initially uncoupled, must be interconnected through controllers to be designed with a constraint on the data…

Optimization and Control · Mathematics 2014-09-23 Christoph Kawan , Jean-Charles Delvenne

We determine stability and attractor properties of random Boolean genetic network models with canalyzing rules for a variety of architectures. For all power law, exponential, and flat in-degree distributions, we find that the networks are…

Molecular Networks · Quantitative Biology 2007-05-23 Stuart Kauffman , Carsten Peterson , Björn Samuelsson , Carl Troein

The concept of control is crucial for effectively understanding and applying biological network models. Key structural features relate to control functions through gene regulation, signaling, or metabolic mechanisms, and computational…

Molecular Networks · Quantitative Biology 2024-11-05 David Murrugarra , Alan Veliz-Cuba , Elena Dimitrova , Claus Kadelka , Matthew Wheeler , Reinhard Laubenbacher

It is known that determining the observability and reconstructibility of Boolean control networks (BCNs) are both NP-hard in the number of nodes of BCNs. In this paper, we use the aggregation method to overcome the challenging complexity…

Optimization and Control · Mathematics 2017-07-24 Kuize Zhang

We study the dynamics of randomly connected networks composed of binary Boolean elements and those composed of binary majority vote elements. We elucidate their differences in both sparsely and densely connected cases. The quickness of…

Disordered Systems and Neural Networks · Physics 2013-03-06 Shun-ichi Amari , Hiroyasu Ando , Taro Toyoizumi , Naoki Masuda

Progress in cell type reprogramming has revived the interest in Waddington's concept of the epigenetic landscape. Recently researchers developed the quasi-potential theory to represent the Waddington's landscape. The Quasi-potential U(x),…

Molecular Networks · Quantitative Biology 2016-05-09 Joseph Xu Zhou , Areejit Samal , Aymeric Fouquier d'Hèrouël , Nathan D. Price , Sui Huang

The tool mpbn offers a Python programming interface for an easy interactive editing of Boolean networks and the efficient computation of elementary properties of their dynamics, including fixed points, trap spaces, and reachability…

Logic in Computer Science · Computer Science 2024-03-12 Van-Giang Trinh , Belaid Benhamou , Loïc Paulevé

One way to model telecommunication networks are static Boolean models. However, dynamics such as node mobility have a significant impact on the performance evaluation of such networks. Consider a Boolean model in $\mathbb{R}^d$ and a random…

Probability · Mathematics 2021-12-24 Nils Aschenbruck , Stephan Bussmann , Hanna Döring

The dynamics of Boolean networks (the N-K model) with scale-free topology are studied here. The existence of a phase transition governed by the value of the scale-free exponent of the network is shown analytically by analyzing the overlap…

Disordered Systems and Neural Networks · Physics 2007-05-23 Maximino Aldana

Gene regulatory networks (GRNs) are increasingly used for explaining biological processes with complex transcriptional regulation. A GRN links the expression levels of a set of genes via regulatory controls that gene products exert on one…

Molecular Networks · Quantitative Biology 2016-06-21 Guy Karlebach

The dynamical organization in the presence of noise of a Boolean neural network with random connections is analyzed. For low levels of noise, the system reaches a stationary state in which the majority of its elements acquire the same…

Disordered Systems and Neural Networks · Physics 2007-05-23 Cristian Huepe , Maximino Aldana

Continuous time Bayesian networks (CTBNs) describe structured stochastic processes with finitely many states that evolve over continuous time. A CTBN is a directed (possibly cyclic) dependency graph over a set of variables, each of which…

Artificial Intelligence · Computer Science 2012-07-09 Uri Nodelman , Daphne Koller , Christian R. Shelton

Temporal networks consist of timestamped directed interactions that may appear continuously in time, yet few studies have directly tackled the continuous-time modeling of networks. Here, we introduce a maximum-entropy approach to temporal…

Social and Information Networks · Computer Science 2026-04-16 Paolo Barucca

Probabilistic Boolean networks (PBNs) is an important mathematical framework widely used for modelling and analysing biological systems. PBNs are suited for modelling large biological systems, which more and more often arise in systems…

Computational Engineering, Finance, and Science · Computer Science 2016-05-04 Andrzej Mizera , Jun Pang , Qixia Yuan