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We consider robust optimal experimental design (ROED) for nonlinear Bayesian inverse problems governed by partial differential equations (PDEs). An optimal design is one that maximizes some utility quantifying the quality of the solution of…

Numerical Analysis · Mathematics 2026-05-01 Abhijit Chowdhary , Ahmed Attia , Alen Alexanderian

The problem of constructing optimal discriminating designs for a class of regression models is considered. We investigate a version of the $T_p$-optimality criterion as introduced by Atkinson and Fedorov [Biometrika 62 (1975a) 289-303]. The…

Statistics Theory · Mathematics 2013-06-07 Dietrich Braess , Holger Dette

Despite many applications, dimensionality reduction in the $\ell_1$-norm is much less understood than in the Euclidean norm. We give two new oblivious dimensionality reduction techniques for the $\ell_1$-norm which improve exponentially…

Data Structures and Algorithms · Computer Science 2021-08-09 Yi Li , David P. Woodruff , Taisuke Yasuda

We apply optimum experimental design (OED) to organic semiconductors modeled by the extended Gaussian disorder model (EGDM) which was developed by Pasveer et al. We present an extended Gummel method to decouple the corresponding system of…

Mathematical Physics · Physics 2015-06-12 Christoph Karl Felix Weiler , Stefan Körkel

In crossover design experiments, the proportional model, where the carryover effects are proportional to their direct treatment effects, has draw attentions in recent years. We discover that the universally optimal design under the…

Statistics Theory · Mathematics 2013-11-13 Wei Zheng

A class of algorithms for the solution of discrete material optimization problems in electromagnetic applications is discussed. The idea behind the algorithm is similar to that of the sequential programming. However, in each major iteration…

Optimization and Control · Mathematics 2017-07-14 Johannes Semmler , Lukas Pflug , Michael Stingl

A singularly perturbed linear system of second order partial differential equations of parabolic reaction-diffusion type with given initial and boundary conditions is considered. The leading term of each equation is multiplied by a small…

Numerical Analysis · Mathematics 2010-08-17 V. Franklin , M. Paramasivam , S. Valarmathi , J. J. H. Miller

We develop polynomial-time algorithms for near-optimal minimax mean estimation under $\ell_2$-squared loss in a Gaussian sequence model under convex constraints. The parameter space is an origin-symmetric, type-2 convex body $K \subset…

Statistics Theory · Mathematics 2026-02-27 Matey Neykov

A shape optimization problem arising from the optimal reinforcement of a membrane by means of one-dimensional stiffeners or from the fastest cooling of a two-dimensional object by means of ``conducting wires'' is considered. The criterion…

Analysis of PDEs · Mathematics 2020-07-14 Giuseppe Buttazzo , Francesco Paolo Maiale

A new non-Hermitian E2-quasi-exactly solvable model is constructed containing two previously known models of this type as limits in one of its three parameters. We identify the optimal finite approximation to the double scaling limit to the…

Quantum Physics · Physics 2016-06-10 Andreas Fring

This article is concerned with an extension of univariate Chebyshev polynomials of the first kind to the multivariate setting, where one chases best approximants to specific monomials by polynomials of lower degree relative to the uniform…

Optimization and Control · Mathematics 2024-10-29 Mareike Dressler , Simon Foucart , Mioara Joldes , Etienne de Klerk , Jean Bernard Lasserre , Yuan Xu

Questions of `how best to acquire data' are essential to modeling and prediction in the natural and social sciences, engineering applications, and beyond. Optimal experimental design (OED) formalizes these questions and creates…

Methodology · Statistics 2026-05-01 Xun Huan , Jayanth Jagalur , Youssef Marzouk

We provide a systematic treatment of $D$-optimal design for binary regression and quantal response models in toxicology studies. For the two-parameter case, we provide an analytical equation (WC equation) for computing the $D$-optimal…

Applications · Statistics 2022-09-28 Elvis Han Cui

Subsampling is commonly used to overcome computational and economical bottlenecks in the analysis of finite populations and massive datasets. Existing methods are often limited in scope and use optimality criteria (e.g., A-optimality) with…

Statistics Theory · Mathematics 2023-04-07 Henrik Imberg , Marina Axelson-Fisk , Johan Jonasson

Optimal design of a Phase I cancer trial can be formulated as a stochastic optimization problem. By making use of recent advances in approximate dynamic programming to tackle the problem, we develop an approximation of the Bayesian optimal…

Methodology · Statistics 2010-12-01 Jay Bartroff , Tze Leung Lai

One of the most common problems in statistical experimentation is computing D-optimal designs on large finite candidate sets. While optimal approximate (i.e., infinite-sample) designs can be efficiently computed using convex methods,…

Computation · Statistics 2026-01-12 Radoslav Harman , Samuel Rosa

Bayesian optimal experimental design (OED) seeks to conduct the most informative experiment under budget constraints to update the prior knowledge of a system to its posterior from the experimental data in a Bayesian framework. Such…

Machine Learning · Computer Science 2024-02-29 Rafael Orozco , Felix J. Herrmann , Peng Chen

Motivated by the problem of optimization of force-field systems in physics using large-scale computer simulations, we consider exploration of a deterministic complex multivariate response surface. The objective is to find input combinations…

Machine Learning · Statistics 2021-09-15 Mert Y. Sengul , Yao Song , Linglin He , Adri C. T. van Duin , Ying Hung , Tirthankar Dasgupta

Optimal signaling schemes in information design (Bayesian persuasion) often involve randomization or disconnected partitions of state space, which might be too intricate to be audited or communicated. We propose explainable information…

Computer Science and Game Theory · Computer Science 2026-02-12 Yiling Chen , Tao Lin , Wei Tang , Jamie Tucker-Foltz

We propose a novel algorithm based on inexact GMRES methods for linear response calculations in density functional theory. Such calculations require iteratively solving a nested linear problem $\mathcal{E} \delta\rho = b$ to obtain the…

Numerical Analysis · Mathematics 2025-10-30 Michael F. Herbst , Bonan Sun