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The ability to detect and size individual nanoparticles with high resolution is crucial to understanding behaviours of single particles and effectively using their strong size-dependent properties to develop innovative products. We report…

We analyze a whispering gallery mode biosensor with a metallic nanorod bound to its surface. It is found that a localized surface plasmon resonance in the nanorod can reduce the optical mode volume of the resonator by as much as four orders…

Optics · Physics 2017-02-01 Jon D. Swaim , Joachim Knittel , Warwick P. Bowen

Label-free detection techniques for single particles and molecules play an important role in basic science, disease diagnostics, and nanomaterial investigations. While traditional fluorescence-based methods offer powerful tools for single…

Optics · Physics 2024-08-20 Shuang Hao , Sartanee Suebka , Judith Su

Detection and characterization of individual nano-scale particles, virions, and pathogens are of paramount importance to human health, homeland security, diagnostic and environmental monitoring[1]. There is a strong demand for…

Optics · Physics 2011-07-06 Lina He , Sahin Kaya Ozdemir , Jiangang Zhu , Woosung Kim , Lan Yang

We, for the first time, report the detection and the size measurement of single nanoparticles (i.e. polystyrene) in aquatic environment using mode splitting in a whispering gallery mode (WGM) optical resonator, namely a microtoroid…

Ultrasensitive optical detection of nanometer-scaled particles is highly desirable for applications in early-stage diagnosis of human diseases, environmental monitoring, and homeland security, but remains extremely difficult due to ultralow…

Biosensing with ferromagnet-based magnetoresistive devices has been dominated by electrical detection of particle-induced changes to the devices' static magnetic configuration. There are however potential advantages to be gained from using…

We demonstrated a biosensing approach which, for the first time, combines the high-sensitivity of whispering gallery modes (WGM) with a metallic nanoparticle based assay. We provided a computational model based on generalized Mie theory to…

Specialized applications of nanoparticles often call for particular, well-characterized particle size distributions in solution. But, this property can prove difficult to measure. High-throughput methods, such as dynamic light scattering,…

Mesoscale and Nanoscale Physics · Physics 2021-09-24 Luke Melo , Angus Hui , Matt Kowal , Eric Boateng , Zahra Poursorkh , Edène Rocheron , Jake Wong , Ashton Christy , Edward Grant

Gold nanorods have unique optical properties, which make them promising candidates for building nano-structured materials using a "bottom-up" strategy. We formulate stable bulk materials with anisotropic optical properties by inserting gold…

Soft Condensed Matter · Physics 2014-06-17 Kostyantyn Slyusarenko , Doru Constantin , Benjamin Abécassis , Patrick Davidson , Corinne Chaéac

Currently, gold nanorods can be synthesized in a wide range of sizes. However, for intended biological applications gold nanorods with approximate dimensions 50 nm x 15 nm are used. We investigate by computer simulation the effect of…

Medical Physics · Physics 2015-06-15 Constantin Ungureanu , Gerben A. Koning , Ton G. van Leeuwen , Srirang Manohar

This paper describes an imaging microscopic technique based on heterodyne digital holography where subwavelength-sized gold colloids can be imaged in cell environment. Surface cellular receptors of 3T3 mouse fibroblasts are labeled with 40…

Surface Plasmon Resonance sensors are a well-established class of sensors which includes a very large variety of materials and detection schemes. However, the development of portable devices is still challenging as due to the intrinsic…

Micro and nanoscale particles are crucial in various fields, from biomedical imaging to environmental processes. While conventional spectroscopy and microscopy methods for characterizing these particles often involve bulky equipment and…

Biological Physics · Physics 2024-11-26 Jie Liao , Maxwell Adolphson , Hangyue Li , Dipayon Kumar Sikder , Chenyang Lu , Lan Yang

Noble metal nanoparticles have been utilized for a vast amount of optical applications. For the applications that used metal nanoparticles as nanosensors and optical labeling, larger radiation damping is preferred (higher optical signal).…

Optics · Physics 2022-03-02 Yanhe Yang , Weihai Ni , Hao Xie , Jian You , Weixiang Ye

We measure the transient absorption of single gold particles with a common-path interferometer. The prompt electronic part of the signal provides high-contrast images for diameters as small as 10 nm. Mechanical vibrations of single…

Other Condensed Matter · Physics 2007-05-23 Meindert A. van Dijk , Markus Lippitz , Michel Orrit

Optomechanical transduction is demonstrated for nanoscale torsional resonators evanescently coupled to optical microdisk whispering gallery mode resonators. The on-chip, integrated devices are measured using a fully fiber-based system,…

Mesoscale and Nanoscale Physics · Physics 2013-05-14 P. H. Kim , C. Doolin , B. D. Hauer , A. J. R. MacDonald , M. R. Freeman , P. E. Barclay , J. P. Davis

The selective optical detection of individual metallic nanoparticles (NPs) with high spatial and temporal resolution is a challenging endeavour, yet is key to the understanding of their optical response and their exploitation in…

Mesoscale and Nanoscale Physics · Physics 2012-06-05 Francesco Masia , Wolfgang Langbein , Paola Borri

Interactions between whispering gallery modes (WGMs) and small nanoparticles are commonly modelled by treating the particle as a point dipole scatterer. This approach is assumed to be accurate as long as the nanoparticle radius, $a$, is…

Plasmonic nanoparticles influence the absorption and emission processes of nearby emitters due to local enhancements of the illuminating radiation and the photonic density of states. Here, we use the plasmon resonance of metal nanoparticles…

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