Plasmonic nanoprobes for stimulated emission depletion microscopy
Abstract
Plasmonic nanoparticles influence the absorption and emission processes of nearby emitters due to local enhancements of the illuminating radiation and the photonic density of states. Here, we use the plasmon resonance of metal nanoparticles in order to enhance the stimulated depletion of excited molecules for super-resolved microscopy. We demonstrate stimulated emission depletion (STED) microscopy with gold nanorods with a long axis of only 26 nm and a width of 8 nm that provide an enhancement of the resolution compared to fluorescent-only probes without plasmonic components irradiated with the same depletion power. These novel nanoparticle-assisted STED probes represent a ~2x10^3 reduction in probe volume compared to previously used nanoparticles and we demonstrate their application to the first plasmon-assisted STED cellular imaging. We also discuss their current limitations.
Keywords
Cite
@article{arxiv.1610.01551,
title = {Plasmonic nanoprobes for stimulated emission depletion microscopy},
author = {Emiliano Cortes and Paloma A. Huidobro and Hugo G. Sinclair and Stina Guldbrand and William J. Peveler and Timothy Davies and Simona Parrinello and Frederik Görlitz and Chris Dunsby and Mark A. A. Neil and Yonatan Sivan and Ivan P. Parkin and Paul M. French and Stefan A. Maier},
journal= {arXiv preprint arXiv:1610.01551},
year = {2016}
}
Comments
30 pages, 15 figures, main text and supplementary information