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Large-area microscopy with submicron resolution is limited by tradeoffs between field of view (FOV), resolution, and imaging speed. Samples are rarely flat across centimeter-scale FOV, which often requires existing solutions to use…

We demonstrate a new computational illumination technique that achieves large space-bandwidth-time product, for quantitative phase imaging of unstained live samples in vitro. Microscope lenses can have either large field of view (FOV) or…

Optics · Physics 2015-10-16 Lei Tian , Ziji Liu , Li-Hao Yeh , Michael Chen , Jingshan Zhong , Laura Waller

In this article, we report an imaging method, termed Fourier ptychographic microscopy (FPM), which iteratively stitches together a number of variably illuminated, low-resolution intensity images in Fourier space to produce a wide-field,…

Optics · Physics 2014-05-02 Guoan Zheng , Roarke Horstmeyer , Changhuei Yang

Whole slide imaging provides a wide field-of-view (FOV) across cross-sections of biopsy or surgery samples, significantly facilitating pathological analysis and clinical diagnosis. Such high-quality images that enable detailed visualization…

Optics · Physics 2024-07-31 Shi Zhao , Haowen Zhou , Siyu Lin , Ruizhi Cao , Changhuei Yang

This article experimentally examines different configurations of a novel multi-camera array microscope (MCAM) imaging technology. The MCAM is based upon a densely packed array of "micro-cameras" to jointly image across a large field-of-view…

Imaging specimens over large scales and with a sub-micron resolution is instrumental to biomedical research. Yet, the number of pixels to form such an image usually exceeds the number of pixels provided by conventional cameras. While most…

Instrumentation and Detectors · Physics 2019-12-03 Gaelle Recher , Pierre Nassoy , Amaury Badon

Fourier ptychographic (FP) microscope is a coherent imaging method that can synthesize an image with a higher bandwidth using multiple low-bandwidth images captured at different spatial frequency regions. The method's demand for multiple…

Optics · Physics 2016-03-25 Jaebum Chung , Hangwen Lu , Xiaoze Ou , Haojiang Zhou , Changhuei Yang

The scanning fiber endoscope (SFE), an ultra-small optical imaging device with a large field-of-view (FOV) for having a clear forward view into the interior of blood vessels, has great potential in the cardio-vascular disease diagnosis and…

We demonstrate a Fourier Imaging system with centimeter field of view(FOV), and 0.0042{\deg}angular resolution at C band, for the entire 180{\deg} radiation angular range. To pursue omnidirectional Fourier imaging without aberration, a…

Optics · Physics 2018-09-07 Jinxi Huang

The fluorescence microscope is one of the most important tools in modern clinical diagnosis and biological science. However, its expense, size and limited field-of-view (FOV) are becoming bottlenecks in key applications such as large-scale…

Optics · Physics 2012-10-10 Shuo Pang , Chao Han , Mihoko Kato , Paul W. Sternberg , Changhuei Yang

A broad range of imaging and sensing technologies in the infrared require large Field-of-View (FoV) operation. To achieve this, traditional refractive systems often employ multiple elements to compensate for aberrations, which leads to…

Developing a chip-based super-resolution imaging technique with large field-of-view (FOV), deep subwavelength resolution, and compatibility for both fluorescent and non-fluorescent samples is desired for material science, biomedicine, and…

Fourier ptychography microscopy (FPM) is a new computational imaging technique that can provide gigapixel images with both high resolution and a wide field of view (FOV). However, time consuming of the data-acquisition process is a critical…

Image and Video Processing · Electrical Eng. & Systems 2018-08-15 Ao Zhou , Ni Chen , Haichao Wang , Guohai Situ

Allying high-resolution with a large field-of-view (FOV) is of great importance in the fields of biology and medicine, but particularly challenging when imaging non-flat living samples such as the human retina. Indeed, high-resolution is…

Miniaturized optical imaging systems typically utilize 2-dimensional (2D) actuators to acquire images over a 2D field of view (FOV). Piezoelectric tubes are most compact, but usually produce sub-millimeter FOVs and are difficult to…

Instrumentation and Detectors · Physics 2023-12-27 Rachel Yixuan Tan , Rachel Chi Kei Chan , Whitney Jia Ying Loh , Kaicheng Liang

Traditional glass-based optics are typically optimized for narrow spectral bands, such as the visible (400-700nm) or shortwave infrared (1000-1800nm). While the emergence of VIS-SWIR sensors (400-1700nm) offers transformative potential,…

Image and Video Processing · Electrical Eng. & Systems 2026-05-04 Vishwanath Saragadam , Niki Nezakati , Amit Roy-Chowdhury , Vivek Boominathan

Metalenses, in order to compete with conventional bulk optics in commercial imaging systems, often require large field of view (FOV) and broadband operation simultaneously. However, strong chromatic and coma aberrations present in common…

In this paper, we present a unique $\text {2D}$ high resolution, compact, low-cost, lightweight, and highly accurate millimeter wave imagery system capable of operating in all weather conditions. We describe millimeter wave imaging process…

Signal Processing · Electrical Eng. & Systems 2025-08-18 Shahrokh Hamidi , M. R. Nezhad-Ahmadi

We report a computational 3D microscopy technique, termed Fourier ptychographic diffraction tomography (FPDT), that iteratively stitches together numerous variably illuminated, low-resolution images acquired with a low-numerical aperture…

Optics · Physics 2020-02-19 Chao Zuo , Jiasong Sun , Jiaji Li , Anand Asundi , Qian Chen

Wide-field high-resolution microscopy requires fast scanning and accurate image mosaicking to cover large fields of view without compromising image quality. However, conventional galvanometric scanning, particularly under sinusoidal…

Image and Video Processing · Electrical Eng. & Systems 2026-02-04 Ziyi Huang , Rosalinda Xiong , Yaning Wang , Jinglun Yu , Jin U. Kang
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