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Fluorescence microscopy has enabled a dramatic development in modern biology by visualizing biological organisms with micrometer scale resolution. However, due to the diffraction limit, sub-micron/nanometer features are difficult to…

Image and Video Processing · Electrical Eng. & Systems 2021-03-10 Varun Mannam , Yide Zhang , Xiaotong Yuan , Scott Howard

The acquisition of high-resolution retinal fundus images with a large field of view (FOV) is challenging due to technological, physiological and economic reasons. This paper proposes a fully automatic framework to reconstruct retinal images…

Computer Vision and Pattern Recognition · Computer Science 2016-02-11 Thomas Köhler , Axel Heinrich , Andreas Maier , Joachim Hornegger , Ralf P. Tornow

In nature, many common insects have compound eyes composed of many small eyes arranged on a curved retina. This kind of vision systems have many advantages, such as small size, large FOV (field of view) and high sensitivity, which have…

Optics · Physics 2020-07-13 Pengcheng Su , Yu Chen , Jiaming Zhang , Yang LI , Chao Yang

Holotomography (HT) has revolutionized quantitative label-free 3D imaging, yet conventional lens-based implementations are fundamentally constrained in field-of-view (FOV) and imaging depth, limiting their utility for critical…

High-content biological microscopy targets high-resolution imaging across large fields-of-view (FOVs). Recent works have demonstrated that computational imaging can provide efficient solutions for high-content microscopy. Here, we use…

Image and Video Processing · Electrical Eng. & Systems 2019-03-28 Li-Hao Yeh , Shwetadwip Chowdhury , Laura Waller

Acquiring high-contrast optical images deep inside biological tissues is still a challenging problem. Confocal microscopy is an important tool for biomedical imaging since it improves image quality by rejecting background signals. However,…

We demonstrate a gigapixel inline digital holographic microscopy using a consumer scanner. The consumer scanner can maximally scan an A4 size image (297mm x 210mm) with 4800 dpi (= 5.29 um), theoretically achieving a resolution of 56,144 x…

We present a new flexible high speed laser scanning confocal microscope and its extension by an astigmatism particle tracking device (APTV). Many standard confocal microscopes use either a single laser beam to scan the sample at relatively…

Although several optical techniques have been recently developed in order to overcome the resolution limit in microscopy, the imaging of sub-wavelength features is still a real challenge. In practise, super-resolution techniques remain…

Physics Education · Physics 2019-07-24 Stephane Perrin , Keshia Badu , Paul Montgomery , Sylvain Lecler

We present a new Multimodal Fiber Array Snapshot Technique (M-FAST), based on an array of 96 compact cameras placed behind a primary objective lens and a fiber bundle array. which is capable of large-area, high-resolution, multi-channel…

Super-resolution fluorescence microscopy is an important tool in biomedical research for its ability to discern features smaller than the diffraction limit. However, due to its difficult implementation and high cost, the universal…

Images recorded below the surface of a finger can have more details and be of higher quality than the conventional surface fingerprint images. This is particularly true when the quality of the surface fingerprints is compromised by, for…

Medical Physics · Physics 2017-09-13 Egidijus Auksorius , A. Claude Boccara

In this paper, the design, realization, and demonstration of a broadband millimeter-wave imaging system based on the synthetic aperture radar technique (SAR) are discussed. The proposed system, operating within the frequency range of…

Applied Physics · Physics 2022-06-01 Fahimeh Sepehripour , Ahmad Shafiei Alavijeh , Mohammad Fakharzadeh , Amin Khavasi

In this paper, we present a high resolution microwave imaging technique using a compact and low cost single channel Frequency Modulated Continuous Wave (FMCW) radar based on Circular Synthetic Aperture Radar (CSAR) technique. We develop an…

Signal Processing · Electrical Eng. & Systems 2024-07-09 Shahrokh Hamidi , Safieddin Safavi-Naeini

Near-diffraction limited imaging and spectroscopy in the visible on large (8-10 meter) class telescopes has proved to be beyond the capabilities of current adaptive optics technologies, even when using laser guide stars. The need for high…

Instrumentation and Methods for Astrophysics · Physics 2015-05-19 Craig Mackay , Tim D. Staley , David King , Frank Suess , Keith Weller

Time-resolved fluorescence imaging is a key tool in biomedical applications, as it allows to non-invasively obtain functional and structural information. However, the big amount of collected data introduces challenges in both acquisition…

We propose a new strategy for obtaining enhanced resolution (FWHM = 0.12 arcsec) deep optical images over a wide field of view. As is well known, this type of image quality can be obtained in principle simply by fast guiding on a small (D =…

Astrophysics · Physics 2009-10-31 N. Kaiser , J. L. Tonry , G. A. Luppino

A full-field chromatic confocal microscopy using a multispectral sensor was developed for quasi-one-shot microscopic 3D surface measurement. An innovative optical configuration employs a digital micromirror device (DMD) and a multispectral…

High efficiency collection of photons emitted by a point source over a wide field-of-view (FoV) is crucial for many applications. Multi-scale optics over improved light collection by utilizing small optical components placed close to the…

In this paper, we present 3D high resolution radar imaging at millimeter-Wave (mmWave) frequencies by means of a combination of virtual Multiple Input Multiple Output (MIMO) Frequency Modulated Continuous Wave (FMCW) Radars and Synthetic…

Signal Processing · Electrical Eng. & Systems 2024-05-20 Shahrokh Hamidi