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In this paper we consider robust models for emergency staff deployment in the event of a flu pandemic. We focus on managing critical staff levels at organizations that must remain operational during such an event, and develop methodologies…

Optimization and Control · Mathematics 2015-07-31 Daniel Bienstock , A. Cecilia Zenteno

The crisis caused by the COVID-19 outbreak around the globe raised an increasing concern about the ongoing emergence of variants of SARS-CoV-2 that may evade the immune response provided by vaccines. New variants appear due to mutation, and…

Populations and Evolution · Quantitative Biology 2022-12-14 M. Ahumada , A. Ledesma-Araujo , Leonardo Gordillo , Juan F. Marín

We demonstrate the applicability of network embedding to vaccine skepticism, a controversial topic of long-past history. With the Covid-19 pandemic outbreak at the end of 2019, the topic is more important than ever. Only a year after the…

Social and Information Networks · Computer Science 2021-10-27 Ferenc Béres , Rita Csoma , Tamás Vilmos Michaletzky , András A. Benczúr

The global spread of avian influenza A viruses in domestic birds is causing dramatic economic and social losses. Various mechanistic models have been developed in an attempt to better understand avian influenza transmission and to evaluate…

Quantitative Methods · Quantitative Biology 2023-03-02 Sébastien Lambert , Billy Bauzile , Amélie Mugnier , Benoit Durand , Timothée Vergne , Mathilde C Paul

Pandemics have the potential to cause immense disruption and damage to communities and societies. In this paper, we model the Influenza Pandemic of 2009. We propose a hybrid model to determine how the pandemic spreads through the world. The…

Populations and Evolution · Quantitative Biology 2010-06-02 Teruhiko Yoneyama , Mukkai S. Krishnamoorthy

Here we treat the transmission of disease through a population as a standard Galton-Watson branching process, modified to take the presence of vaccination into account. Vaccination reduces the number of secondary infections produced per…

Probability · Mathematics 2021-06-15 Arni S. R. Srinivasa Rao , Chris T. Bauch

Accurate real-time tracking of influenza outbreaks helps public health officials make timely and meaningful decisions that could save lives. We propose an influenza tracking model, ARGO (AutoRegression with GOogle search data), that uses…

Applications · Statistics 2015-11-17 Shihao Yang , Mauricio Santillana , S. C. Kou

We study an optimal control problem where the objective is to find the best vaccine allocation during an epidemic outbreak. The epidemic dynamics is described by an age-structured SIR model with nonlocal interactions. Both the infection and…

Optimization and Control · Mathematics 2026-05-19 Luís Almeida , Romain Ducasse , Elisa Paparelli

A mathematical model of COVID-19 with minimal compartments is developed. The model is simple enough to fit data on confirmed cases, estimate the hidden infection figure and incorporate the effect of vaccination. With the effect of the new…

Populations and Evolution · Quantitative Biology 2021-03-05 Randy L. Caga-anan , Michelle N. Raza , Grace Shelda G. Labrador , Ephrime B. Metillo

The potential waning of the vaccination immunity to COVID-19 could pose threats to public health, as it is tenable that the timing of such waning would synchronize with the near-complete restoration of normalcy. Should also testing be…

Populations and Evolution · Quantitative Biology 2022-01-28 Agnieszka Truszkowska , Lorenzo Zino , Sachit Butail , Emanuele Caroppo , Zhong-Ping Jiang , Alessandro Rizzo , Maurizio Porfiri

RNA virus populations will undergo processes of mutation and selection resulting in a mixed population of viral particles. High throughput sequencing of a viral population subsequently contains a mixed signal of the underlying clones. We…

Populations and Evolution · Quantitative Biology 2014-07-31 Donatien Fotso-Chedom , Pablo R. Murcia , Chris D. Greenman

India's mass vaccination efforts have been slow due to high levels of vaccine hesitancy. This study uses data from an online discrete choice experiment with 1371 respondents to rigorously examine the factors shaping vaccine preference in…

Physics and Society · Physics 2021-08-19 Prateek Bansal , Alok Raj , Dhirendra Mani Shukla , Naveen Sunder

Infectious diseases are still a major global burden for modern society causing 13 million deaths annually. One way to reduce the morbidity and mortality rates from infectious diseases is through preventative or targeted vaccinations.…

Social and Information Networks · Computer Science 2021-01-27 Md Shahzamal , Raja Jurdak , Bernard Mans , Frank de Hoog , Dean Paini

We introduce a model of protein evolution to explain limitations in the immune system response to vaccination and disease. The phenomenon of original antigenic sin, wherein vaccination creates memory sequences that can \emph{increase}…

Statistical Mechanics · Physics 2007-05-23 Michael W. Deem , Ha Youn Lee

Influenza is an acute respiratory illness that occurs virtually every year and results in substantial disease, death and expense. Detection of Influenza in its earliest stage would facilitate timely action that could reduce the spread of…

Social and Information Networks · Computer Science 2013-11-20 Jiwei Li , Claire Cardie

Epidemic risk assessment poses inherent challenges, with traditional approaches often failing to balance health outcomes and economic constraints. This paper presents a data-driven decision support tool that models epidemiological dynamics…

Applications · Statistics 2025-11-24 Chang Zhai , Ping Chen , Zhuo Jin , David Pitt

A new age-distributed immuno-epidemiological model with information-based vaccine uptake suggested in this work represents a system of integro-differential equations for the numbers of susceptible individuals, infected individuals,…

Populations and Evolution · Quantitative Biology 2024-04-02 Samiran Ghosh , Malay Banerjee , Vitaly Volpert

The Influenza A virus belongs to the Orthomyxoviridae family. Influenza virus infection occurs yearly in all countries of the world. It usually kills between 250,000 and 500,000 people and causes severe illness in millions more. Over the…

Cell Behavior · Quantitative Biology 2014-11-25 Juliana Silva Capitanio , Richard W. Wozniak

Face masks have been widely used as a protective measure against COVID-19. However, pre-pandemic empirical studies have produced mixed statistical results on the effectiveness of masks against respiratory viruses. The implications of the…

Quantitative Methods · Quantitative Biology 2022-11-24 Pratyush K. Kollepara , Alexander F. Siegenfeld , Nassim Nicholas Taleb , Yaneer Bar-Yam

The effectiveness of vaccination highly depends on the choice of individuals to vaccinate, even if the same number of individuals are vaccinated. Vaccinating individuals with high centrality measures such as betweenness centrality (BC) and…

Physics and Society · Physics 2021-12-30 Bukyoung Jhun
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