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Experimental studies of microbial communities routinely reveal that they have multiple stable states. While each of these states is generally resilient, certain perturbations such as antibiotics, probiotics and diet shifts, result in…

Populations and Evolution · Quantitative Biology 2019-02-15 Akshit Goyal , Veronika Dubinkina , Sergei Maslov

Mathematical models represent one of the fundamental ways of studying nature. In special, epidemic models have shown to be particularly useful in the understanding of the course of diseases and in the planning effective control policies. A…

Physics and Society · Physics 2022-10-19 Paulo C. Ventura , Eric K. Tokuda , Luciano da F. Costa , Francisco A. Rodrigues

We study the continuous absorbing-state phase transition in the one-dimensional diffusive epidemic process via mean-field theory and Monte Carlo simulation. In this model, particles of two species (A and B) hop on a lattice and undergo…

Statistical Mechanics · Physics 2009-11-11 Daniel Souza Maia , Ronald Dickman

The well-established methodology for the estimation of hidden semi-Markov models (HSMMs) as hidden Markov models (HMMs) with extended state spaces is further developed to incorporate covariate influences across all aspects of the state…

Methodology · Statistics 2024-05-24 Jan-Ole Koslik

The paper deals with the setting where two viruses (say virus 1 and virus 2) coexist in a population, and they are not necessarily mutually exclusive, in the sense that infection due to one virus does not preclude the possibility of…

Populations and Evolution · Quantitative Biology 2024-07-12 Sebin Gracy , Philip E. Paré , Ji Liu , Henrik Sandberg , Carolyn L. Beck , Karl Henrik Johansson , Tamer Başar

We adapt the article of Forien, Pang, Pardoux and Zotsa: Arxiv preprint Arxiv2210.04667(2022), on epidemic models with varying infectivity and waning immunity, to incorporate the memory of the last infection. To this end, we introduce a…

Probability · Mathematics 2025-05-02 Hélène Guérin , Arsene Brice Zotsa-Ngoufack

Host-parasitoid population dynamics is often probed using a semi-discrete/hybrid modeling framework. Here, the update functions in the discrete-time model connecting year-to-year changes in the population densities are obtained by solving…

Populations and Evolution · Quantitative Biology 2020-01-01 Brooks Emerick , Abhyudai Singh

Given a collection of entities (or nodes) in a network and our intermittent observations of activities from each entity, an important problem is to learn the hidden edges depicting directional relationships among these entities. Here, we…

Machine Learning · Statistics 2017-08-01 Triet M Le

Hidden Markov models (HMMs) are widely applied in studies where a discrete-valued process of interest is observed indirectly. They have for example been used to model behaviour from human and animal tracking data, disease status from…

Methodology · Statistics 2025-05-22 Théo Michelot

Competing risks model time to first event and type of first event. An example from hospital epidemiology is the incidence of hospital-acquired infection, which has to account for hospital discharge of non-infected patients as a competing…

Methodology · Statistics 2013-04-09 Arthur Allignol , Jan Beyersmann , Thomas Gerds , Aurélien Latouche

Multi-state survival analysis considers several potential events of interest along a disease pathway. Such analyses are crucial to model complex patient trajectories and are increasingly being used in epidemiological and health economic…

Methodology · Statistics 2021-04-30 Jonathan Broomfield , Caroline E. Weibull , Michael J. Crowther

Interaction patterns among individuals play vital roles in spreading infectious diseases. Understanding these patterns and integrating their impact in modeling diffusion dynamics of infectious diseases are important for epidemiological…

Social and Information Networks · Computer Science 2018-04-02 Md Shahzamal , Raja Jurdak , Bernard Mans , Ahmad El Shoghri , Frank De Hoog

A particular challenge for disease progression modeling is the heterogeneity of a disease and its manifestations in the patients. Existing approaches often assume the presence of a single disease progression characteristics which is…

Machine Learning · Computer Science 2022-07-26 Taha Ceritli , Andrew P. Creagh , David A. Clifton

Inferring time-varying networks is important to understand the development and evolution of interactions over time. However, the vast majority of currently used models assume direct measurements of node states, which are often difficult to…

Applications · Statistics 2014-05-06 Xin Wang , Ke Yuan , Christoph Hellmayr , Wei Liu , Florian Markowetz

Hidden Markov models (HMMs) have been used increasingly to understand how movement patterns of animals arise from behavioural states. An animal is assumed to transition between behavioural states through time, as described by transition…

Quantitative Methods · Quantitative Biology 2025-10-07 Théo Michelot , Emma Storey

This paper studies a distributed continuous-time bi-virus model in which two competing viruses spread over a network consisting of multiple groups of individuals. Limiting behaviors of the network are characterized by analyzing the…

Optimization and Control · Mathematics 2019-01-04 Ji Liu , Philip E. Pare , Angelia Nedich , Choon Yik Tang , Carolyn L. Beck , Tamer Basar

We investigate to what extent the interaction dynamics of a population of wild house mouse (Mus musculus domesticus) in their environment can be explained by a simple stochastic model. We use a Markov chain model to describe the transitions…

Quantitative Methods · Quantitative Biology 2012-12-05 Nicolas Perony , Barbara König , Frank Schweitzer

We present a hidden Markov model that describes variation in an animal's position associated with varying levels of activity in action potential spike trains of individual place cell neurons. The model incorporates a coarse-graining of…

Applications · Statistics 2014-12-22 Marc Box , Matt W. Jones , Nick Whiteley

Antagonistic coevolution between hosts and parasites can have a major impact on host population structures, and hence on the evolution of social traits. Using stochastic modelling techniques in the context of bacteria-virus interactions, we…

Populations and Evolution · Quantitative Biology 2012-10-09 Benjamin J. Z. Quigley , Diana García López , Angus Buckling , Alan J. McKane , Sam P. Brown

Our study is devoted to a four-compartment epidemic model of a constant population of independent random walkers. Each walker is in one of four compartments (S-susceptible, C-infected but not infectious (period of incubation), I-infected…

Populations and Evolution · Quantitative Biology 2023-08-29 Teo Granger , Thomas Michelitsch , Bernard Collet , Michael Bestehorn , Alejandro Riascos
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