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Consider a supercritical birth and death process where the children acquire mutations. We study the mutation rates along the ancestral lineages in a sample of size $n$ from the population at time $T$. The mutation rate is time-inhomogenous…

Probability · Mathematics 2024-02-27 Yubo Shuai

We propose a change in focus from the prevalent paradigm based on the branching property as a tool to analyze the structure of population models, to one based on the self-similarity property, which we also introduce for the first time in…

Probability · Mathematics 2026-04-15 Arno Siri-Jégousse , Alejandro Hernández Wences

The influence of time-dependent fitnesses on the infinite population dynamics of simple genetic algorithms (without crossover) is analyzed. Based on general arguments, a schematic phase diagram is constructed that allows one to characterize…

Biological Physics · Physics 2007-05-23 Christopher Ronnewinkel , Claus O. Wilke , Thomas Martinetz

We present a technique to study normalizing strategies when termination is asymptotic, that is, it appears as a limit, as opposite to reaching a normal form in a finite number of steps. Asymptotic termination occurs in several settings,…

Logic in Computer Science · Computer Science 2022-05-24 Claudia Faggian , Giulio Guerrieri

Sweepstakes reproduction may be generated by chance matching of reproduction with favorable environmental conditions. Gene genealogies generated by sweepstakes reproduction are in the domain of attraction of multiple-merger coalescents…

Probability · Mathematics 2026-01-15 Bjarki Eldon

The nested Kingman coalescent describes the ancestral tree of a population undergoing neutral evolution at the level of individuals and at the level of species, simultaneously. We study the speed at which the number of lineages descends…

Probability · Mathematics 2018-03-28 Airam Blancas Benítez , Tim Rogers , Jason Schweinsberg , Arno Siri-Jégousse

We investigate Bayesian non-parametric inference of the $\Lambda$-measure of $\Lambda$-coalescent processes with recurrent mutation, parametrised by probability measures on the unit interval. We give verifiable criteria on the prior for…

Methodology · Statistics 2019-08-13 Jere Koskela , Paul A. Jenkins , Dario Spanò

When an advantageous mutation occurs in a population, the favorable allele may spread to the entire population in a short time, an event known as a selective sweep. As a result, when we sample $n$ individuals from a population and trace…

Probability · Mathematics 2007-05-23 Rick Durrett , Jason Schweinsberg

Longitudinal molecular data of rapidly evolving viruses and pathogens provide information about disease spread and complement traditional surveillance approaches based on case count data. The coalescent is used to model the genealogy that…

Applications · Statistics 2020-09-07 Lorenzo Cappello , Julia A. Palacios

We derive exact formulae for the allele frequency spectrum under the coalescent with mutation, conditioned on allele counts at some fixed time in the past. We consider unlinked biallelic markers mutating according to a finite sites, or…

Populations and Evolution · Quantitative Biology 2011-09-19 David Bryant , Arindam RoyChoudhury , Remco Bouckaert , Joseph Felsenstein , Noah Rosenberg

In this paper, we review recent results of ours concerning branching processes with general lifetimes and neutral mutations, under the infinitely many alleles model, where mutations can occur either at birth of individuals or at a constant…

Probability · Mathematics 2012-11-29 Nicolas Champagnat , Amaury Lambert , Mathieu Richard

Many population genetic models have been developed for the purpose of inferring population size and growth rates from random samples of genetic data. We examine two popular approaches to this problem, the coalescent and the…

Populations and Evolution · Quantitative Biology 2014-08-29 Erik M. Volz , Simon DW Frost

We study a model of a population with individuals sampled from different species. The Yule-$\Lambda$ nested coalescent describes the genealogy of the sample when each species merges with another randomly chosen species with a constant rate…

Probability · Mathematics 2024-01-05 Toni Gui

We consider neutral evolution of a large population subject to changes in its population size. For a population with a time-variable carrying capacity we have computed the distributions of the total branch lengths of its sample genealogies.…

Populations and Evolution · Quantitative Biology 2012-06-13 A. Eriksson , B. Mehlig , M. Rafajlovic , S. Sagitov

We present and discuss new importance sampling schemes for the approximate computation of the sample probability of observed genetic types in the infinitely many sites model from population genetics. More specifically, we extend the…

Probability · Mathematics 2011-05-11 Matthias Birkner , Jochen Blath , Matthias Steinruecken

$\Lambda$-coalescents model genealogies of samples of individuals from a large population by means of a family tree whose branches have lengths. The tree's leaves represent the individuals, and the lengths of the adjacent edges indicate the…

Probability · Mathematics 2019-09-12 Christina S. Diehl , Götz Kersting

We consider a population model where individuals behave independently from each other and whose genealogy is described by a chronological tree called splitting tree. The individuals have i.i.d. (non-exponential) lifetime durations and give…

Probability · Mathematics 2014-05-20 Mathieu Richard

We study tree lengths in $\Lambda$-coalescents without a dust component from a sample of $n$ individuals. For the total length of all branches and the total length of all external branches we present laws of large numbers in full…

Probability · Mathematics 2019-01-23 Christina S. Diehl , Götz Kersting

We consider a continuous population whose dynamics is described by the standard stationary Fleming-Viot process, so that the genealogy of $n$ uniformly sampled individuals is distributed as the Kingman $n$-coalescent. In this note, we study…

Probability · Mathematics 2016-11-07 Amaury Lambert , Emmanuel Schertzer

It is becoming routine to obtain datasets on DNA sequence variation across several thousands of chromosomes, providing unprecedented opportunity to infer the underlying biological and demographic forces. Such data make it vital to study…

Populations and Evolution · Quantitative Biology 2015-06-24 Paul A. Jenkins , Jonas W. Mueller , Yun S. Song