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We describe and solve a discrete persistent chain model of protein binding on DNA, involving an extra sigma_i s at a site i of the DNA. This variable takes the value 1 or 0 depending on whether the site is occupied by a protein or not. In…

Statistical Mechanics · Physics 2015-05-27 Pui-Man Lam , Yi Zhen

Spatial heterogeneity in the elastic properties of soft random solids is investigated via a two-pronged approach. First, a nonlocal phenomenological model for the elastic free energy is examined. This features a quenched random kernel,…

Disordered Systems and Neural Networks · Physics 2011-12-06 Xiaoming Mao , Paul M. Goldbart , Xiangjun Xing , Annette Zippelius

This paper presents an electromechanical analysis of the nonlinear static response and the superimposed small-amplitude wave characteristics in an infinite periodic compressible dielectric elastomer (DE) laminate subjected to electrostatic…

Soft Condensed Matter · Physics 2021-07-26 Yingjie Chen , Bin Wu , Yipin Su , Weiqiu Chen

Dissipaton-equation-of-motion (DEOM) theory [Y. J. Yan, J. Chem. Phys. 140, 054105 (2014)] is an exact and nonperturbative many-particle method for open quantum systems. The existing dissipaton algebra treats also the dynamics of hybrid…

Chemical Physics · Physics 2020-01-24 Yao Wang , Rui-Xue Xu , YiJing Yan

In this paper, an online multiscale model reduction method is presented for stochastic partial differential equations (SPDEs) with multiplicative noise, where the diffusion coefficient is spatially multiscale and the noise perturbation…

Numerical Analysis · Mathematics 2022-04-26 Lijian Jiang , Mengnan Li , Meng Zhao

A three-dimensional simulation model is proposed here to study the erosive wear of structure caused by solid particles, which accounts for the accumulation of surface deformation and degradation during the erosion process. Although there…

Fluid Dynamics · Physics 2025-03-04 Vinh D. X. Nguyen , A. Kiet Tieu , Damien Andre , Hongtao Zhu

The relation between thermal fluctuations and the mechanical response of a free membrane has been explored in great detail, both theoretically and experimentally. However, understanding this relationship for membranes, locally pinned by…

Biological Physics · Physics 2019-04-03 Josip A. Janeš , Henning Stumpf , Daniel Schmidt , Udo Seifert , Ana-Sunčana Smith

We develop a continuum elastic approach to examining the bending mechanics of semiflexible filaments with a local internal degree of freedom that couples to the bending modulus. We apply this model to study the nonlinear mechanics of a…

Soft Condensed Matter · Physics 2013-02-12 Arthur A. Evans , Alex J. Levine

We provide a detailed multiscale analysis of a system of particles interacting through a dynamical network of links. Starting from a microscopic model, via the mean field limit, we formally derive coupled kinetic equations for the particle…

Analysis of PDEs · Mathematics 2016-07-14 Julien Barré , Pierre Degond , Ewelina Zatorska

In simulations of metallic interfaces, a critical aspect of metallic behavior is missing from the some of the most widely used classical molecular dynamics force fields. We present a modification of the embedded atom method (EAM) which…

Materials Science · Physics 2019-04-02 Hemanta Bhattarai , Kathie E. Newman , J. Daniel Gezelter

Ensemble learning has proven effective in improving predictive performance and estimating uncertainty in neural networks. However, conventional ensemble methods often suffer from redundant parameter usage and computational inefficiencies…

Machine Learning · Computer Science 2024-12-23 Arnav Kharbanda , Advait Chandorkar

Collagen networks provide the main structural component of most tissues and represent an important ingredient for bio-mimetic materials for bio-medical applications. Here we study the mechanical properties of stiff collagen networks derived…

We study kinks in the electronic dispersion of a generic strongly correlated system by dynamic mean-field theory (DMFT). The focus is on doped systems away from particle-hole symmetry where valence fluctuations matter potentially. Three…

Strongly Correlated Electrons · Physics 2015-03-19 Patrick Grete , Sebastian Schmitt , Carsten Raas , Frithjof B. Anders , Götz S. Uhrig

We study the enzymatic degradation of an elastic fiber under tension using an an isotropic random-walk model, coupled with binding-unbinding reactions that weaken the fiber. The fiber is represented by a chain of elastic springs in series,…

Statistical Mechanics · Physics 2009-10-08 Ascânio D. Araújo , Arnab Majumdar , Harikrishnan Parame swaran , Béla Suki

We developed a deep generative model-based variational free energy approach to the equations of state of dense hydrogen. We employ a normalizing flow network to model the proton Boltzmann distribution and a fermionic neural network to model…

Strongly Correlated Electrons · Physics 2023-09-26 Hao Xie , Zi-Hang Li , Han Wang , Linfeng Zhang , Lei Wang

We simulate the electrical properties of a device realized by a G protein coupled receptor (GPCR), embedded in its membrane and in contact with two metallic electrodes through which an external voltage is applied. To this purpose, recently,…

Quantitative Methods · Quantitative Biology 2009-11-11 C. Pennetta , V. Akimov , E. Alfinito , L. Reggiani , G. Gomila , G. Ferrari , L. Fumagalli , M. Sampietro

Accurate protein structure prediction from amino-acid sequences is critical to better understanding the protein function. Recent advances in this area largely benefit from more precise inter-residue distance and orientation predictions,…

Machine Learning · Computer Science 2021-06-01 Jiaxiang Wu , Shitong Luo , Tao Shen , Haidong Lan , Sheng Wang , Junzhou Huang

Sheared granular layers undergoing stick slip behavior are broadly employed to study the physics and dynamics of earthquakes. Here, a two dimensional implementation of the combined finite discrete element method (FDEM), which merges the…

The outcome of an epidemic is closely related to the network of interactions between the individuals. Likewise, protein functions depend on the 3D arrangement of their residues and on the underlying energetic interaction network. Borrowing…

Biomolecules · Quantitative Biology 2021-07-19 Mattia Miotto , Lorenzo Di Rienzo , Pietro Corsi , Giancarlo Ruocco , Domenico Raimondo , Edoardo Milanetti

The dynamics of a metallic particle confined between charged walls is studied. One wall is fixed and the other moves smoothly and periodically in time. Dissipation is considered by assuming a friction produced by the contact between the…

Chaotic Dynamics · Physics 2013-12-12 Denis Gouvêa Ladeira , Edson Denis Leonel
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