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We introduce a minimalistic model based on dynamic node deletion and node duplication with heterodimerisation. The model is intended to capture the essential features of the evolution of protein interaction networks. We derive an exact…

Biological Physics · Physics 2009-11-13 Nadia Farid , Kim Christensen

We explore the possibilities of using energy minimization for the numerical modeling of strain localization in solids as a sharp discontinuity in the displacement field. For this purpose, we consider (regularized) strong discontinuity…

Machine Learning · Computer Science 2025-01-14 Omar León , Víctor Rivera , Angel Vázquez-Patiño , Jacinto Ulloa , Esteban Samaniego

The relentless pursuit of miniaturization and performance enhancement in electronic devices has led to a fundamental challenge in the field of circuit design and simulation: how to accurately account for the inherent stochastic nature of…

Machine Learning · Computer Science 2023-11-13 Jack Hutchins , Shamiul Alam , Dana S. Rampini , Bakhrom G. Oripov , Adam N. McCaughan , Ahmedullah Aziz

In thermodynamic equilibrium, the fluctuation-dissipation theorem links thermal fluctuations and dissipation. Biological systems, however, are driven out of equilibrium by internal processes that produce additional, active fluctuations.…

Soft Condensed Matter · Physics 2026-01-29 Ashot Matevosyan , Frank Jülicher , Ricard Alert

In this paper, a multiscale virtual particle based elastic network model (MVP-ENM) is proposed for biomolecular normal mode analysis. The multiscale virtual particle model is proposed for the discretization of biomolecular density data in…

Biomolecules · Quantitative Biology 2019-03-13 Kelin Xia

Discrete element modelling (DEM) is one of the most efficient computational approaches to the fracture processes of heterogeneous materials on mesoscopic scales. From the dynamics of single crack propagation through the statistics of crack…

Materials Science · Physics 2015-09-09 Humberto A. Carmona , Falk K. Wittel , Ferenc Kun

A review of the present state of investigations of the pseudospin-electron model (PEM), which is used in the theory of strongly correlated electron systems, is given. The model is used to describe the systems with the locally anharmonic…

Strongly Correlated Electrons · Physics 2016-11-23 Ihor Stasyuk

Theoretical and experimental studies have shown that the fluctuations of in vivo systems break the fluctuation-dissipation theorem. One can thus ask what information is contained in the correlation functions of protein concentrations and…

Chemical Physics · Physics 2016-08-24 Hélène Berthoumieux

We present an edge-based framework for the study of geometric elastic network models to model mechanical interactions in physical systems. We use a formulation in the edge space, instead of the usual node-centric approach, to characterise…

Chemical Physics · Physics 2020-01-08 Maxwell Hodges , Sophia N Yaliraki , Mauricio Barahona

Dense Associative Memory networks (DenseAMs) unify several popular paradigms in Artificial Intelligence (AI), such as Hopfield Networks, transformers, and diffusion models, while casting their computational properties into the language of…

Statistical Mechanics · Physics 2026-04-07 Spencer Rooke , Dmitry Krotov , Vijay Balasubramanian , David Wolpert

Micro-Electro-Mechanical Systems (MEMS) normally have fixed or moving structures with cross-sections of the order of microns ($\mu m$) and lengths of the order of tens or hundreds of microns. These structures are often plates or array of…

Computational Physics · Physics 2007-05-23 N. Majumdar , S. Mukhopadhyay

We analyze the fluctuations of an electronic thermal current across an idealized molecular junction. The focus here will be on the spectral features of the resulting heat fluctuations. By use of the Green functionmethod we derive an…

Mesoscale and Nanoscale Physics · Physics 2013-12-02 Fei Zhan , Sergey Denisov , Peter Hänggi

This paper discusses the elastic behavior of a very long crosslinked polyelectrolyte chain (Debye-H\"uckel chain), which is weakly charged. Therefore the response of the crosslinked chain (network) on an external constant force $f$ acting…

Soft Condensed Matter · Physics 2009-10-30 J. Wilder , T. A. Vilgis

A pore network modeling (PNM) framework for the simulation of transport of charged species, such as ions, in porous media is presented. It includes the Nernst-Planck (NP) equations for each charged species in the electrolytic solution in…

Computational Physics · Physics 2020-05-20 Mehrez Agnaou , Mohammad Amin Sadeghi , Thomas George Tranter , Jeff Gostick

The dynamics of stochastic reaction networks within cells are inevitably modulated by factors considered extrinsic to the network such as for instance the fluctuations in ribsome copy numbers for a gene regulatory network. While several…

Quantitative Methods · Quantitative Biology 2015-06-19 Christoph Zechner , Heinz Koeppl

Usage, manipulation, transport, delivery, and mixing of granular or particulate media, comprised of spherical or polyhedral particles, is commonly encountered in industrial sectors of construction (cement and rock fragments), pharmaceutics…

Computational Engineering, Finance, and Science · Computer Science 2021-02-25 Prashant K. Jha , Prathamesh S. Desai , Debdeep Bhattacharya , Robert Lipton

We propose an efficient method to build a simple discrete element model (DEM) that accurately simulates the oscillation of a continuum beam. The DEM is based on the Timoshenko beam theory of slender cylindrical members and their…

Other Condensed Matter · Physics 2023-09-22 Yeongtae Jang , Eunho Kim , Jinkyu Yang , Junsuk Rho

We introduce and study a new model of interacting neural networks, incorporating the spatial dimension (e.g. position of neurons across the cortex) and some learning processes. The dynamic of each neural network is described via the elapsed…

Analysis of PDEs · Mathematics 2020-09-03 Delphine Salort , Nicolas Torres

The two approaches to analyzing the large strain behavior of rubbery networks are phenomenologically, using strain energy functions drawn from continuum mechanics, and molecular models, which apply statistical mechanics to compute the…

Soft Condensed Matter · Physics 2011-04-11 C. M. Roland

The fluctuating dynamics of a network about its stable, noise-free steady state are theoretically investigated. Various causes of non-equilibrium dynamics are identified in terms of the properties and symmetry of the network connections and…

Statistical Mechanics · Physics 2026-04-15 Pik-Yin Lai