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We propose to model the dynamics of metabolic networks from a systems biology point of view by four dynamical structure elements: potential function, transverse matrix, degradation matrix, and stochastic force. These four elements are…

Molecular Networks · Quantitative Biology 2007-05-23 P. Ao

This work presents a physics-informed neural network (PINN) based framework to model the strain-rate and temperature dependence of the deformation fields in elastic-viscoplastic solids. To avoid unbalanced back-propagated gradients during…

Materials Science · Physics 2022-11-24 Rajat Arora , Pratik Kakkar , Biswadip Dey , Amit Chakraborty

The aim of this work is two-fold: to design devices for passive electric damping of structural vibrations by distributed piezoelectric transducers and electric networks, and to experimentally validate the effectiveness of such a damping…

Mathematical Physics · Physics 2010-07-13 F. dell'Isola , C. Maurini , M. Porfiri

Proteins change their charge state through protonation and redox reactions as well as through binding charged ligands. The free energy of these reactions are dominated by solvation and electrostatic energies and modulated by protein…

Biomolecules · Quantitative Biology 2016-02-26 Marilyn R. Gunner , Nathan A. Baker

We study a model describing the force-extension curves of modular proteins, nucleic acids, and other biomolecules made out of several single units or modules. At a mesoscopic level of description, the configuration of the system is given by…

Statistical Mechanics · Physics 2016-10-19 L. L. Bonilla , A. Carpio , A. Prados

We present calculations of the correlation energies of crystalline solids and isolated systems within the adiabatic-connection fluctuation-dissipation formulation of density-functional theory. We perform a quantitative comparison of a set…

Materials Science · Physics 2016-07-29 Christopher E. Patrick , Kristian S. Thygesen

Nonlinear elastic effects play an important role in the dynamics of microelectromechanical systems (MEMS). Duffing oscillator is widely used as an archetypical model of mechanical resonators with nonlinear elastic behavior. In contrast,…

Other Condensed Matter · Physics 2009-11-12 S. Zaitsev , O. Shtempluck , E. Buks , O. Gottlieb

This work presents a physics-conditioned latent diffusion model tailored for dynamical downscaling of atmospheric data, with a focus on reconstructing high-resolution 2-m temperature fields. Building upon a pre-existing diffusion…

Machine Learning · Computer Science 2025-10-29 Paul Rosu , Muchang Bahng , Erick Jiang , Rico Zhu , Vahid Tarokh

We aim to identify the control principles governing the adaptable formation of non-equilibrium structures in actomyosin networks. We build a phenomenological model and predict that biasing the energy dissipated by molecular motors should…

We introduce a model for the dynamic self-organization of the electric grid. The model is characterized by a conserved magnitude, energy, that can travel following the links of the network to satisfy nodes' load. The load fluctuates in time…

Physics and Society · Physics 2016-08-16 Alessandro Scirè , Idán Tuval , Víctor M. Eguíluz

We employ simulations of model proteins to study folding on rugged energy landscapes. We construct ``first-passage'' networks as the system transitions from unfolded to native states. The nodes and bonds in these networks correspond to…

Soft Condensed Matter · Physics 2015-05-13 Gregg Lois , J. Blawzdziewicz , Corey S. O'Hern

Discrete mesoscale network models, in which explicitly modeled polymer chains are replaced by implicit pairwise potentials, are capable of predicting the macroscale mechanical response of polymeric materials such as elastomers and gels,…

Soft Condensed Matter · Physics 2024-07-16 Robert J. Wagner , Meredith N. Silberstein

Translating metabolic networks into dynamic models is difficult if kinetic constants are unknown. Structural Kinetic Modelling (SKM) replaces reaction elasticities by independent random numbers. Here I propose a variant that accounts for…

Molecular Networks · Quantitative Biology 2022-03-08 Wolfram Liebermeister

For a wide range of applications, we need DEM simulations of granular matter in contact with flexible elastic boundaries. We present a novel method to describe the interaction between granular particles and a flexible elastic membrane.…

Soft Condensed Matter · Physics 2022-10-20 Holger Goetz , Thorsten Pöschel

In recent years, the rapid advancement of deep learning has significantly impacted various fields, particularly in solving partial differential equations (PDEs) in the realm of solid mechanics, benefiting greatly from the remarkable…

Machine Learning · Computer Science 2024-09-17 Yizheng Wang , Jia Sun , Timon Rabczuk , Yinghua Liu

A new variational method for studying the equilibrium states of an interacting particles system has been proposed. The statistical description of the system is realized by means of a density matrix. This method is used for description of…

General Physics · Physics 2014-12-19 Boris Bondarev

Physics-Informed Neural Networks present a novel approach in SciML that integrates physical laws in the form of partial differential equations directly into the NN through soft constraints in the loss function. This work studies the…

Neural and Evolutionary Computing · Computer Science 2026-02-17 Suhas Suresh Bharadwaj , Reuben Thomas Thovelil

In this perspective article, we discuss the scenario of dynamically emergent correlation (DEC) arising in classical and quantum noninteracting systems when they are subjected to a common fluctuating stochastic environment. The key property…

Statistical Mechanics · Physics 2026-03-04 Satya N. Majumdar , Gregory Schehr

Due to the time-scale limitations of all-atom simulation of proteins, there has been substantial interest in coarse-grained approaches. Some methods, like "Resolution Exchange," [E. Lyman et al., Phys. Rev. Lett. 96, 028105 (2006)] can…

Biological Physics · Physics 2007-05-23 F. Marty Ytreberg , Svetlana Kh. Aroutiounian , Daniel M. Zuckerman

We use three-dimensional discrete dislocation dynamics simulations (DDD) to study the evolution of interfacial dislocation network (IDN) in particle-strengthened alloy systems subjected to constant stress at high temperatures. We have…

Materials Science · Physics 2019-04-19 Tushar Jogi , Saswata Bhattacharya
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