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The non-population conserving SIR (SIR-NC) model to describe the spread of infections in a community is proposed and studied. Unlike the standard SIR model, SIR-NC does not assume population conservation. Although similar in form to the…

Optimization and Control · Mathematics 2020-11-06 Vivek S. Borkar , D. Manjunath

In the face of serious infectious diseases, governments endeavour to implement containment measures such as public vaccination at a macroscopic level. Meanwhile, individuals tend to protect themselves by avoiding contacts with infections at…

Physics and Society · Physics 2016-10-20 Xiao-Long Peng , Xin-Jian Xu , Michael Small , Xinchu Fu , Zhen Jin

Real-time vaccination following an outbreak can effectively mitigate the damage caused by an infectious disease. However, in many cases, available resources are insufficient to vaccinate the entire at-risk population, logistics result in…

Populations and Evolution · Quantitative Biology 2016-03-29 Chantal Nguyen , Jean M. Carlson

Taking precautions before or during the start of a virus outbreak can heavily reduce the number of infected. The question which individuals should be immunized in order to mitigate the impact of the virus on the rest of population has…

Social and Information Networks · Computer Science 2013-03-06 V. V. Kashirin , L. J. Dijkstra

The Susceptible-Infected-Recovered (SIR) model is the cornerstone of epidemiological models. However, this specification depends on two parameters only, which implies a lack of flexibility and the difficulty to replicate the volatile…

Populations and Evolution · Quantitative Biology 2020-11-17 Christian Gourieroux , Yang Lu

We study the interaction between epidemic spreading and a vaccination process. We assume that, similar to the disease spreading, also the vaccination process occurs through direct contact, i.e., it follows the standard…

Physics and Society · Physics 2020-06-22 Mozhgan Khanjanianpak , Nahid Azimi-Tafreshi , Claudio Castellano

Ebola virus is one of the most virulent pathogens for humans. We present a mathematical description of different Susceptible-Exposed-Infectious-Recovered (SEIR) models. By using mathematical modeling and analysis, the latest major outbreak…

Populations and Evolution · Quantitative Biology 2017-08-01 Amira Rachah , Delfim F. M. Torres

The success of an infectious disease to invade a population is strongly controlled by the population's specific connectivity structure. Here a network model is presented as an aid in understanding the role of social behavior and…

Cellular Automata and Lattice Gases · Physics 2007-07-10 Anna Litvak-Hinenzon , Lewi Stone

We study the minimum eradication time problem for controlled Susceptible-Infected-Recovered (SIR) epidemic models that incorporate vaccination control and time-varying infected and recovery rates. Unlike the SIR model with constant rates,…

Analysis of PDEs · Mathematics 2023-11-27 Jiwoong Jang , Yeoneung Kim

We present a detailed set-based analysis of the well-known SIR and SEIR epidemic models subjected to hard caps on the proportion of infective individuals, and bounds on the allowable intervention strategies, such as social distancing,…

Optimization and Control · Mathematics 2021-11-17 Willem Esterhuizen , Jean Lévine , Stefan Streif

Vaccinations are an important tool in the prevention of disease. Vaccinations are generally voluntary for each member of a population and vaccination decisions are influenced by individual risk perceptions and contact structures within…

Physics and Society · Physics 2025-04-07 Kausutua Tjikundi , Mark Broom

In this paper, we consider an adaptive optimal control problem for an SIR/V epidemic model with human behavioral effects.We develop a model where effective management of infectious diseases are monitored by the means of non pharmaceutical…

Physics and Society · Physics 2025-12-09 Nuruzzaman Rahat , Abid Hossain , Muntasir Alam

Recent Covid-19 pandemic has demonstrated the need of efficient epidemic outbreak management. We study the optimal control problem of minimizing the fraction of infected population by applying vaccination and treatment control strategies,…

Social and Information Networks · Computer Science 2021-12-07 Jagtap Kalyani Devendra , Kundan Kandhway

This work is concerned with epidemiological models defined on networks, which highlight the prominent role of the social contact network of a given population in the spread of infectious diseases. In particular, we address the modelling and…

Numerical Analysis · Mathematics 2023-03-07 Giovanni Naldi , Giuseppe Patane'

We consider the simple epidemiological SIS model for a general heterogeneous population introduced by Lajmanovich and Yorke (1976) in finite dimension, and its infinite dimensional generalization we introduced in previous works. In this…

Dynamical Systems · Mathematics 2022-11-29 Jean-François Delmas , Dylan Dronnier , Pierre-André Zitt

Containing an epidemic at its origin is the most desirable mitigation. Epidemics have often originated in rural areas, with rural communities among the first affected. Disease dynamics in rural regions have received limited attention, and…

We present a data-driven optimal control approach which integrates the reported partial data with the epidemic dynamics for COVID-19. We use a basic Susceptible-Exposed-Infectious-Recovered (SEIR) model, the model parameters are…

Optimization and Control · Mathematics 2020-12-22 Hailiang Liu , Xuping Tian

We formulate a generalized susceptible exposed infectious recovered (SEIR) model on a graph, describing the population dynamics of an open crowded place with an arbitrary topology. As a sample calculation, we discuss three simple cases,…

Physics and Society · Physics 2020-12-18 Andrea Nava , Alessandro Papa , Marco Rossi , Domenico Giuliano

The SIR model is the cornerstone model for mathematical epidemiology, explaining key epidemic features such as the second-order transition between disease-free and epidemic states, the initial exponential growth of outbreaks or the…

Populations and Evolution · Quantitative Biology 2026-03-20 Santiago Lamata-Otín , Alex Arenas , Jesús Gómez-Gardeñes , David Soriano-Paños

Heterogeneity is an important property of any population experiencing a disease. Here we apply general methods of the theory of heterogeneous populations to the simplest mathematical models in epidemiology. In particular, an SIR…

Populations and Evolution · Quantitative Biology 2012-02-28 Artem S Novozhilov
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