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We present low-scaling algorithms for $GW$ and constrained random phase approximation based on a symmetry-adapted interpolative separable density fitting (ISDF) procedure that incorporates the space-group symmetries of crystalline systems.…

Materials Science · Physics 2024-01-24 Chia-Nan Yeh , Miguel A. Morales

In this work, we propose FFDP, a set of IO-aware non-GEMM fused kernels supplemented with a distributed framework for image registration at unprecedented scales. Image registration is an inverse problem fundamental to biomedical and life…

Computer Vision and Pattern Recognition · Computer Science 2025-09-30 Rohit Jena , Vedant Zope , Pratik Chaudhari , James C. Gee

Mixed-precision quantization is a promising approach for compressing large language models under tight memory budgets. However, existing mixed-precision methods typically suffer from one of two limitations: they either rely on expensive…

Machine Learning · Computer Science 2026-02-03 Xin Nie , Haicheng Zhang , Liang Dong , Beining Feng , Jinhong Weng , Guiling Sun

We developed a novel method of creating intensity modulated proton arc therapy (IMPAT) plans that uses computing resources efficiently and may offer a dosimetric benefit for patients with ependymoma or similar tumor geometries. Our IMPAT…

Smoothed Particle Hydrodynamics (SPH) is essential for modeling complex large-deformation problems across various applications, requiring significant computational power. A major portion of SPH computation time is dedicated to the Nearest…

Distributed, Parallel, and Cluster Computing · Computer Science 2024-01-23 Zirui Mao , Xinyi Li , Shenyang Hu , Ganesh Gopalakrishnan , Ang Li

Intensity-modulated radiation therapy (IMRT) allows for the design of customized, highly-conformal treatments for cancer patients. Creating IMRT treatment plans, however, is a mathematically complex process, which is often tackled in…

Optimization and Control · Mathematics 2022-03-18 Danielle A. Ripsman , Thomas G. Purdie , Timothy C. Y. Chan , Houra Mahmoudzadeh

Statistical iterative reconstruction is expected to improve the image quality of megavoltage computed tomography (MVCT). However, one of the challenges of iterative reconstruction is its large computational cost. The purpose of this work is…

In this study, two proton beam delivery designs, passive scattering proton therapy (PSPT) and pencil beam scanning (PBS), were quantitatively compared in terms of dosimetric indices. The GATE Monte Carlo code was used to simulate the proton…

Medical Physics · Physics 2022-09-21 A. Asadi , A. Akhavanallaf , S. A. Hosseini , H. Zaidi

Photomultiplier tubes (PMTs) are widely deployed at neutrino and dark matter experiments for photon counting. When multiple photons hit a PMT consecutively, their photo-electron (PE) pulses pile up to hinder the precise measurements of the…

High Energy Physics - Experiment · Physics 2025-09-12 Yuyi Wang , Aiqiang Zhang , Yiyang Wu , Benda Xu , Xuewei Liu , Jiajie Chen , Zhe Wang , Shaomin Chen

We determine how prediction methods combine with optimization methods in two-stage knowledge-based planning (KBP) pipelines to produce radiation therapy treatment plans. We trained two dose prediction methods, a generative adversarial…

Medical Physics · Physics 2019-11-01 Aaron Babier , Rafid Mahmood , Andrea L. McNiven , Adam Diamant , Timothy C. Y. Chan

We propose to develop deep learning models that can predict Pareto optimal dose distributions by using any given set of beam angles, along with patient anatomy, as input to train the deep neural networks. We implement and compare two deep…

Medical Physics · Physics 2021-01-27 Gyanendra Bohara , Azar Sadeghnejad Barkousaraie , Steve Jiang , Dan Nguyen

Conventional beam orientation optimization (BOO) algorithms for IMRT assume that the same set of beam angles is used for all treatment fractions. In this paper we present a BOO formulation based on group sparsity that simultaneously…

Medical Physics · Physics 2018-03-14 Daniel O'Connor , Dan Nguyen , Dan Ruan , Victoria Yu , Ke Sheng

Radiotherapy treatment planning currently requires many trail-and-error iterations between the planner and treatment planning system, as well as between the planner and physician for discussion/consultation. The physician's preferences for…

Medical Physics · Physics 2019-08-01 Dan Nguyen , Azar Sadeghnejad Barkousaraie , Chenyang Shen , Xun Jia , Steve Jiang

The steep dose gradients obtained with pencil beam scanning allow for precise tumor targeting at the cost of high sensitivity to uncertainties. Robust optimization is commonly applied to mitigate uncertainties in density and patient setup,…

Medical Physics · Physics 2024-11-26 Ivar Bengtsson , Anders Forsgren , Albin Fredriksson , Ye Zhang

A multiply-accumulate (MAC) operation is the main computation unit for DSP applications. DSP blocks are one of the efficient solutions to implement MACs in FPGA's. However, since the DSP blocks have wide multiplier and adder blocks, MAC…

Hardware Architecture · Computer Science 2021-10-26 Ercan Kalali , Rene van Leuken

Computed tomography from a low radiation dose (LDCT) is challenging due to high noise in the projection data. Popular approaches for LDCT image reconstruction are two-stage methods, typically consisting of the filtered backprojection (FBP)…

Image and Video Processing · Electrical Eng. & Systems 2025-03-17 Tim Selig , Thomas März , Martin Storath , Andreas Weinmann

Early detection of lung cancer is crucial for effective treatment and relies on accurate volumetric assessment of pulmonary nodules in CT scans. Traditional methods, such as consolidation-to-tumor ratio (CTR) and spherical approximation,…

Image and Video Processing · Electrical Eng. & Systems 2025-08-29 Yihan Zhou , Haocheng Huang , Yue Yu , Jianhui Shang

Correlation Plenoptic Imaging (CPI) is a novel technological imaging modality enabling to overcome drawbacks of standard plenoptic devices, while preserving their advantages. However, a major challenge in view of real-time application of…

We present a GPU-accelerated cosmological simulation code, PhotoNs-GPU, based on algorithm of Particle Mesh Fast Multipole Method (PM-FMM), and focus on the GPU utilization and optimization. A proper interpolated method for truncated…

Instrumentation and Methods for Astrophysics · Physics 2021-12-28 Qiao Wang , Chen Meng

Monolithic crystals are examined as an alternative to segmented scintillator arrays in positron emission tomography (PET). Monoliths provide good energy, timing and spatial resolution including intrinsic depth of interaction (DOI) encoding.…

Medical Physics · Physics 2018-12-05 Florian Müller , David Schug , Patrick Hallen , Jan Grahe , Volkmar Schulz