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Filtered backpropagation (FBPP) is a well-known technique used for Diffraction Tomography (DT). For accurate reconstruction of a complex image using FBPP, full $360^{\circ}$ angular coverage is necessary. However, it has been shown that…

Medical Physics · Physics 2016-05-09 Pavel Roy Paladhi , Ashoke Sinha , Amin Tayebi , Lalita Udpa

In the precision medicine era, there is a growing need for precision radiotherapy where the planned radiation dose needs to be optimally determined by considering a myriad of patient-specific information in order to ensure treatment…

Machine Learning · Statistics 2022-02-10 Wenbo Sun , Dipesh Niraula , Issam El Naqa , Randall K Ten Haken , Ivo D Dinov , Kyle Cuneo , Judy Jin

This study develops and validates a patient-specific Monte Carlo (MC) dosimetry framework for propagation-based phase-contrast breast CT (BCT) at the Imaging and Medical Beamline (IMBL), ANSTO Australian Synchrotron, for accurate mean…

Purpose: HDR brachytherapy is a widely adopted modality for cancer treatment. However, it is not free from error and uncertainty. In-vivo dosimetry (IVD) is the only technique that can confirm correct dose delivery. This study details and…

Medical Physics · Physics 2025-12-10 Chahrazed Ghannoudi , Marie-Claude Lavallee , Benjamin Cote , Luc Beaulieu

We introduce the first end-to-end learning-based solution to near-field Photometric Stereo (PS), where the light sources are close to the object of interest. This setup is especially useful for reconstructing large immobile objects. Our…

Computer Vision and Pattern Recognition · Computer Science 2022-03-31 Daniel Lichy , Soumyadip Sengupta , David W. Jacobs

To tackle the exponentially increasing throughput of Next-Generation Sequencing (NGS), most of the existing short-read aligners can be configured to favor speed in trade of accuracy and sensitivity. SOAP3-dp, through leveraging the…

The integral quality monitor (IQM) system compares the signal measured with a large volume chamber mounted to the linear accelerator's head to the signal calculated using the patient DICOM RT plan for patient-specific quality assurance…

Adaptive mesh refinement (AMR) reduces computational costs in CFD by concentrating resolution where needed, but efficiently embedding complex, non-aligned geometries on GPUs remains challenging. We present a GPU-native algorithm for…

Computational Engineering, Finance, and Science · Computer Science 2026-04-28 Khodr Jaber , Ebenezer E. Essel , Pierre E. Sullivan

Treatment planning is currently a patient specific, time-consuming, and resource demanding task in radiotherapy. Dose-volume histogram (DVH) prediction plays a critical role in automating this process. The geometric relationship between…

Artificial Intelligence · Computer Science 2024-02-13 Zehao Dong , Yixin Chen , Hiram Gay , Yao Hao , Geoffrey D. Hugo , Pamela Samson , Tianyu Zhao

Purpose: The FLASH effect, which reduces the radiosensitivity of healthy tissue while maintaining tumor control at high dose rates, has shown potential for improving radiation therapy. Conformal FLASH proton therapy involves advanced…

Medical Physics · Physics 2023-04-13 Sylvain Deffet , Edmond Sterpin

Objective: Quantify geometric and dosimetric accuracy of a novel prostate MR-to-MR deformable image registration (DIR) approach to support MR-guided adaptive radiation therapy dose accumulation. Approach: We evaluated DIR accuracy in 25…

Deep learning has facilitated the automation of radiotherapy by predicting accurate dose distribution maps. However, existing methods fail to derive the desirable radiotherapy parameters that can be directly input into the treatment…

Computer Vision and Pattern Recognition · Computer Science 2024-03-01 Jiaqi Cui , Yuanyuan Xu , Jianghong Xiao , Yuchen Fei , Jiliu Zhou , Xingcheng Peng , Yan Wang

Purpose: To develop a novel aperture-based algorithm for volumetric modulated arc therapy (VMAT) treatment plan optimization with high quality and high efficiency. Methods: The VMAT optimization problem is formulated as a large-scale convex…

Medical Physics · Physics 2015-05-19 Chunhua Men , H. Edwin Romeijn , Xun Jia , Steve B. Jiang

The use of digitally reconstructed radiographs (DRRs) to solve inverse problems such as slice-to-volume registration and 3D reconstruction is well-studied in preoperative settings. In intraoperative imaging, the utility of DRRs is limited…

Computer Vision and Pattern Recognition · Computer Science 2022-08-29 Vivek Gopalakrishnan , Polina Golland

This study investigates the applicability of 3D dose predictions from a model trained on one modality to a cross-modality automated planning workflow. Additionally, we explore the impact of integrating a multi-criteria optimizer on adapting…

Medical Physics · Physics 2024-02-26 Gregory Szalkowski , Xuanang Xu , Shiva Das , Pew-Thian Yap , Jun Lian

Currently, deep learning (DL) has achieved the automatic prediction of dose distribution in radiotherapy planning, enhancing its efficiency and quality. However, existing methods suffer from the over-smoothing problem for their commonly…

Image and Video Processing · Electrical Eng. & Systems 2023-11-07 Zhenghao Feng , Lu Wen , Peng Wang , Binyu Yan , Xi Wu , Jiliu Zhou , Yan Wang

This paper presents a Graphics Processing Units (GPUs) acceleration method of an iterative scheme for gas-kinetic model equations. Unlike the previous GPU parallelization of explicit kinetic schemes, this work features a fast converging…

Computational Physics · Physics 2020-01-08 Lianhua Zhu , Peng Wang , Songze Chen , Zhaoli Guo , Yonghao Zhang

Background: Accurate and fast dose calculation is essential for optimizing carbon ion therapy. Existing machine learning (ML) models have been developed for other radiotherapy modalities. They use patient data with uniform CT imaging…

In this study, the absorbed dose calculation for the cerebral region is refined using the Geant4 software, along with the ROOT and GATE programs. This approach provides a detailed statistical analysis of positron trajectories within a water…

Medical Physics · Physics 2025-05-06 Walter Sabalza-Castillejo , Miguel Martin-Landrove

Accurate and reliable Magnetic Resonance Imaging (MRI) analysis is particularly important for adaptive radiotherapy, a recent medical advance capable of improving cancer diagnosis and treatment. Recent studies have shown that IVIM-NET, a…

Hardware Architecture · Computer Science 2024-07-09 Zehuan Zhang , Matej Genci , Hongxiang Fan , Andreas Wetscherek , Wayne Luk