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Related papers: Towards a Conceptual Framework for Innate Immunity

200 papers

Deep learning-based AI models have been extensively applied in genomics, achieving remarkable success across diverse applications. As these models gain prominence, there exists an urgent need for interpretability methods to establish…

Genomics · Quantitative Biology 2025-05-16 Chenyu Wang , Chaoying Zuo , Zihan Su , Yuhang Xing , Lu Li , Maojun Wang , Zeyu Zhang

Dendritic cells are antigen presenting cells that provide a vital link between the innate and adaptive immune system. Research into this family of cells has revealed that they perform the role of coordinating T-cell based immune responses,…

Artificial Intelligence · Computer Science 2010-07-05 Julie Greensmith , Uwe Aickelin , Steve Cayzer

The premise of the Multi-disciplinary Conference on Reinforcement Learning and Decision Making is that multiple disciplines share an interest in goal-directed decision making over time. The idea of this paper is to sharpen and deepen this…

Artificial Intelligence · Computer Science 2022-06-07 Richard S. Sutton

"Intrinsic motivation" refers to the capacity for intelligent systems to be motivated endogenously, i.e. by features of agential architecture itself rather than by learned associations between action and reward. This paper views active…

Neurons and Cognition · Quantitative Biology 2025-02-14 Alex B. Kiefer

In this thesis, the uses of Artificial Immune Systems (AIS) in Machine learning is studded. the thesis focus on some of immune inspired algorithms such as clonal selection algorithm and artificial immune network. The effect of changing the…

Neural and Evolutionary Computing · Computer Science 2017-09-14 Mohammad Tarek Al Muallim

Among features of real immune responses which occur when antigens invade a body,there are two remarkable features. One is that the amount of antibodies produced in the secondary invasion by the same antigens is more than 10 times larger…

Populations and Evolution · Quantitative Biology 2007-05-23 Mika Yoshida , Kinji Fuchikami , Tatsuya Uezu

The cellular adaptive immune response plays a key role in resolving influenza infection. Experiments where individuals are successively infected with different strains within a short timeframe provide insight into the underlying viral…

Populations and Evolution · Quantitative Biology 2016-11-24 Ada W. C. Yan , Pengxing Cao , Jane M. Heffernan , Jodie McVernon , Kylie M. Quinn , Nicole L. La Gruta , Karen L. Laurie , James M. McCaw

Organisms have evolved immune systems that can counter pathogenic threats. The adaptive immune system in vertebrates consists of a diverse repertoire of immune receptors that can dynamically reorganize to specifically target the…

Populations and Evolution · Quantitative Biology 2024-10-29 Quinn N Bellamy , Zachary Montague , Luca Peliti , Armita Nourmohammad

Recent advances in large pretrained models have led to their widespread integration as core components in modern software systems. The trend is expected to continue in the foreseeable future. Unlike traditional software systems governed by…

Software Engineering · Computer Science 2025-07-18 Dongming Jin , Zhi Jin , Linyu Li , Xiaohong Chen

Time perception - how humans and animals perceive the passage of time - forms the basis for important cognitive skills such as decision-making, planning, and communication. In this work, we propose a framework for examining the mechanisms…

Systems and Control · Electrical Eng. & Systems 2023-11-08 Inês Lourenço , Robert Mattila , Rodrigo Ventura , Bo Wahlberg

Building autonomous -- i.e., choosing goals based on one's needs -- and adaptive -- i.e., surviving in ever-changing environments -- agents has been a holy grail of artificial intelligence (AI). A living organism is a prime example of such…

Artificial Intelligence · Computer Science 2025-03-18 Sungwoo Lee , Younghyun Oh , Hyunhoe An , Hyebhin Yoon , Karl J. Friston , Seok Jun Hong , Choong-Wan Woo

The mathematical models used to capture features of complex, biological systems are typically non-linear, meaning that there are no generally valid simple relationships between their outputs and the data that might be used to validate them.…

Quantitative Methods · Quantitative Biology 2014-04-23 Thomas House

This paper aims at identifying emerging computational intelligence trends for the design and modeling of complex biometric-enabled infrastructure and systems. Biometric-enabled systems are evolving towards deep learning and deep inference…

Computer Vision and Pattern Recognition · Computer Science 2020-06-23 Svetlana Yanushkevich , Shawn Eastwood , Kenneth Lai , Vlad Shmerko

Model immunization aims to pre-train models that are difficult to fine-tune on harmful tasks while retaining their utility on other non-harmful tasks. Though prior work has shown empirical evidence for immunizing text-to-image models, the…

Machine Learning · Computer Science 2025-05-30 Amber Yijia Zheng , Cedar Site Bai , Brian Bullins , Raymond A. Yeh

The standard assumptions that underlie many conceptual and quantitative frameworks do not hold for many complex physical, biological, and social systems. Complex systems science clarifies when and why such assumptions fail and provides…

Physics and Society · Physics 2020-11-11 Alexander F. Siegenfeld , Yaneer Bar-Yam

Artificial intelligence (AI) has transformed various sectors and institutions, including education and healthcare. Although AI offers immense potential for innovation and problem solving, its integration also raises significant ethical…

Computers and Society · Computer Science 2024-12-05 William Franz Lamberti

A new detailed mathematical model for dynamics of immune response to hepatitis B is proposed, which takes into account contributions from innate and adaptive immune responses, as well as cytokines. Stability analysis of different steady…

Populations and Evolution · Quantitative Biology 2018-05-16 F. Fatehi Chenar , Y. N. Kyrychko , K. B. Blyuss

We present ideas about creating a next generation Intrusion Detection System based on the latest immunological theories. The central challenge with computer security is determining the difference between normal and potentially harmful…

Neural and Evolutionary Computing · Computer Science 2010-07-05 Uwe Aickelin , Peter Bentley , Steve Cayzer , Kim Jungwon , Julie McLeod

Despite significant achievements and current interest in machine learning and artificial intelligence, the quest for a theory of intelligence, allowing general and efficient problem solving, has done little progress. This work tries to…

Artificial Intelligence · Computer Science 2020-12-18 Abel Torres Montoya

Biological systems, unlike physical or chemical systems, are characterized by the very inhomogeneous distribution of their components. The immune system, in particular, is notable for self-organizing its structure. Classically, the dynamics…

Statistical Mechanics · Physics 2007-05-23 Yoram Louzoun , Sorin Solomon , Henri Atlan , Irun R. Cohen
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